ID A0A1S2YHR0_CICAR Unreviewed; 209 AA.
AC A0A1S2YHR0;
DT 12-APR-2017, integrated into UniProtKB/TrEMBL.
DT 12-APR-2017, sequence version 1.
DT 27-MAR-2024, entry version 31.
DE RecName: Full=Vacuolar protein sorting-associated protein 28 homolog {ECO:0000256|PIRNR:PIRNR017535};
GN Name=LOC101509752 {ECO:0000313|RefSeq:XP_004504985.1};
OS Cicer arietinum (Chickpea) (Garbanzo).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; fabids; Fabales; Fabaceae; Papilionoideae; 50 kb inversion clade;
OC NPAAA clade; Hologalegina; IRL clade; Cicereae; Cicer.
OX NCBI_TaxID=3827 {ECO:0000313|Proteomes:UP000087171, ECO:0000313|RefSeq:XP_004504985.1};
RN [1] {ECO:0000313|RefSeq:XP_004504985.1}
RP IDENTIFICATION.
RC TISSUE=Etiolated seedlings {ECO:0000313|RefSeq:XP_004504985.1};
RG RefSeq;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- FUNCTION: Component of the ESCRT-I complex (endosomal sorting complex
CC required for transport I), a regulator of vesicular trafficking
CC process. {ECO:0000256|PIRNR:PIRNR017535}.
CC -!- SUBCELLULAR LOCATION: Endosome {ECO:0000256|ARBA:ARBA00004177}.
CC -!- SIMILARITY: Belongs to the VPS28 family.
CC {ECO:0000256|PIRNR:PIRNR017535, ECO:0000256|PROSITE-ProRule:PRU00642}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR RefSeq; XP_004504985.1; XM_004504928.3.
DR AlphaFoldDB; A0A1S2YHR0; -.
DR STRING; 3827.A0A1S2YHR0; -.
DR PaxDb; 3827-XP_004504985-1; -.
DR GeneID; 101509752; -.
DR KEGG; cam:101509752; -.
DR eggNOG; KOG3284; Eukaryota.
DR OrthoDB; 5486880at2759; -.
DR Proteomes; UP000087171; Chromosome Ca6.
DR GO; GO:0000813; C:ESCRT I complex; IEA:UniProtKB-UniRule.
DR GO; GO:0032509; P:endosome transport via multivesicular body sorting pathway; IEA:InterPro.
DR GO; GO:0015031; P:protein transport; IEA:UniProtKB-UniRule.
DR Gene3D; 1.20.120.1130; -; 1.
DR Gene3D; 1.20.1440.200; -; 1.
DR InterPro; IPR037202; ESCRT_assembly_dom.
DR InterPro; IPR007143; Vps28.
DR InterPro; IPR017899; VPS28_C.
DR InterPro; IPR037206; VPS28_C_sf.
DR InterPro; IPR017898; VPS28_N.
DR InterPro; IPR038358; VPS28_N_sf.
DR PANTHER; PTHR12937; VACUOLAR PROTEIN SORTING 28, ISOFORM 2 VPS28; 1.
DR PANTHER; PTHR12937:SF0; VACUOLAR PROTEIN SORTING-ASSOCIATED PROTEIN 28 HOMOLOG; 1.
DR Pfam; PF03997; VPS28; 1.
DR PIRSF; PIRSF017535; VPS28; 1.
DR SUPFAM; SSF140111; Endosomal sorting complex assembly domain; 1.
DR SUPFAM; SSF140427; VPS28 C-terminal domain-like; 1.
DR PROSITE; PS51310; VPS28_C; 1.
DR PROSITE; PS51313; VPS28_N; 1.
PE 3: Inferred from homology;
KW Endosome {ECO:0000256|ARBA:ARBA00022753, ECO:0000256|PIRNR:PIRNR017535};
KW Protein transport {ECO:0000256|ARBA:ARBA00022927,
KW ECO:0000256|PIRNR:PIRNR017535};
KW Reference proteome {ECO:0000313|Proteomes:UP000087171};
KW Transport {ECO:0000256|ARBA:ARBA00022448, ECO:0000256|PIRNR:PIRNR017535}.
FT DOMAIN 1..99
FT /note="VPS28 N-terminal"
FT /evidence="ECO:0000259|PROSITE:PS51313"
FT DOMAIN 109..205
FT /note="VPS28 C-terminal"
FT /evidence="ECO:0000259|PROSITE:PS51310"
SQ SEQUENCE 209 AA; 23366 MW; AA6167E6930DD1BD CRC64;
MEVKLWNDKR EREMYDNFAE LYAIIKATER LEKAYVRDII SPQEYEIECQ KLIAHFKTLA
STLKDTVPSI ERFADTYRME CPAAINRLVV SGVPATVEHR AAAAAGASTS AAVVAECVQN
FITSMDSLKL NMVAVDQVHP LLSDLYASLN KLTILPPDFE GKTKMKDWIA RLSKMGAADE
LTEQQARQLH FDLESSYNSF MAALPNAGT
//
