ID A0A1S2YYP1_CICAR Unreviewed; 437 AA.
AC A0A1S2YYP1;
DT 12-APR-2017, integrated into UniProtKB/TrEMBL.
DT 12-APR-2017, sequence version 1.
DT 27-MAR-2024, entry version 28.
DE RecName: Full=Protein phosphatase {ECO:0000256|RuleBase:RU366020};
DE EC=3.1.3.16 {ECO:0000256|RuleBase:RU366020};
GN Name=LOC101493059 {ECO:0000313|RefSeq:XP_004512015.1};
OS Cicer arietinum (Chickpea) (Garbanzo).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; fabids; Fabales; Fabaceae; Papilionoideae; 50 kb inversion clade;
OC NPAAA clade; Hologalegina; IRL clade; Cicereae; Cicer.
OX NCBI_TaxID=3827 {ECO:0000313|Proteomes:UP000087171, ECO:0000313|RefSeq:XP_004512015.1};
RN [1] {ECO:0000313|RefSeq:XP_004512015.1}
RP IDENTIFICATION.
RC TISSUE=Etiolated seedlings {ECO:0000313|RefSeq:XP_004512015.1};
RG RefSeq;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=H2O + O-phospho-L-seryl-[protein] = L-seryl-[protein] +
CC phosphate; Xref=Rhea:RHEA:20629, Rhea:RHEA-COMP:9863, Rhea:RHEA-
CC COMP:11604, ChEBI:CHEBI:15377, ChEBI:CHEBI:29999, ChEBI:CHEBI:43474,
CC ChEBI:CHEBI:83421; EC=3.1.3.16;
CC Evidence={ECO:0000256|RuleBase:RU366020};
CC -!- CATALYTIC ACTIVITY:
CC Reaction=H2O + O-phospho-L-threonyl-[protein] = L-threonyl-[protein] +
CC phosphate; Xref=Rhea:RHEA:47004, Rhea:RHEA-COMP:11060, Rhea:RHEA-
CC COMP:11605, ChEBI:CHEBI:15377, ChEBI:CHEBI:30013, ChEBI:CHEBI:43474,
CC ChEBI:CHEBI:61977; EC=3.1.3.16;
CC Evidence={ECO:0000256|RuleBase:RU366020};
CC -!- COFACTOR:
CC Name=Mg(2+); Xref=ChEBI:CHEBI:18420;
CC Evidence={ECO:0000256|RuleBase:RU366020};
CC -!- COFACTOR:
CC Name=Mn(2+); Xref=ChEBI:CHEBI:29035;
CC Evidence={ECO:0000256|RuleBase:RU366020};
CC -!- SIMILARITY: Belongs to the PP2C family.
CC {ECO:0000256|RuleBase:RU366020}.
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DR RefSeq; XP_004512015.1; XM_004511958.3.
DR AlphaFoldDB; A0A1S2YYP1; -.
DR PaxDb; 3827-XP_004512015-1; -.
DR GeneID; 101493059; -.
DR KEGG; cam:101493059; -.
DR eggNOG; KOG1379; Eukaryota.
DR OrthoDB; 11009at2759; -.
DR Proteomes; UP000087171; Chromosome Ca8.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-UniRule.
DR GO; GO:0017018; F:myosin phosphatase activity; IEA:UniProtKB-EC.
DR Gene3D; 3.60.40.10; PPM-type phosphatase domain; 2.
DR InterPro; IPR036457; PPM-type-like_dom_sf.
DR InterPro; IPR001932; PPM-type_phosphatase-like_dom.
DR InterPro; IPR039123; PPTC7.
DR PANTHER; PTHR12320; PROTEIN PHOSPHATASE 2C; 1.
DR PANTHER; PTHR12320:SF83; PROTEIN PHOSPHATASE 2C 55-RELATED; 1.
DR Pfam; PF13672; PP2C_2; 1.
DR SMART; SM00331; PP2C_SIG; 1.
DR SMART; SM00332; PP2Cc; 1.
DR SUPFAM; SSF81606; PP2C-like; 1.
DR PROSITE; PS51746; PPM_2; 1.
PE 3: Inferred from homology;
KW Hydrolase {ECO:0000256|RuleBase:RU366020};
KW Magnesium {ECO:0000256|RuleBase:RU366020};
KW Manganese {ECO:0000256|RuleBase:RU366020};
KW Metal-binding {ECO:0000256|RuleBase:RU366020};
KW Protein phosphatase {ECO:0000256|RuleBase:RU366020};
KW Reference proteome {ECO:0000313|Proteomes:UP000087171}.
FT DOMAIN 192..431
FT /note="PPM-type phosphatase"
FT /evidence="ECO:0000259|PROSITE:PS51746"
SQ SEQUENCE 437 AA; 46940 MW; 36683E9DA01F5BCB CRC64;
MLCGSSNNLS KLNATIYYHI HEAITSQKTL PISLYRNKKN PVLYLPSLSN KFGRKSMASS
SSNAMLGDVY VDELISSYGG VQDFTKPAGV YFKERSHKGL MRGSVSLRRP HQLLYGPLNF
GRSNFYSSWS IQNSGLVHGP WQKNFSASSS ACCLARAEHD VSLDSSLPDE QPGNSSTWPN
LTTLGRKPLK MLSGSCYLPH PDKEATGGED AHFICTDEQA IGVADGVGGW ADVGVNAGLF
AQELISNSVR AVQEEPKGSF NPLRVLEKAH SNTKAKGSST ACIVALADEA LNAINLGDSG
FIVIRGGSII FKSPVQQHDF NFTYQLESGN GGDLPSSGEV FTIPVAPGDV IVAGTDGLFD
NLYNNDITAV VVNATRARLE PQTTAQKIAA LARQRALDKK RPSPFSAAAL EAGYRYYGGK
LDDITVVVSY ISSSISE
//
