ID A0A1S2YZB0_CICAR Unreviewed; 915 AA.
AC A0A1S2YZB0;
DT 12-APR-2017, integrated into UniProtKB/TrEMBL.
DT 12-APR-2017, sequence version 1.
DT 27-MAR-2024, entry version 27.
DE RecName: Full=Glutamate receptor {ECO:0000256|PIRNR:PIRNR037090};
GN Name=LOC101501975 {ECO:0000313|RefSeq:XP_004512282.1};
OS Cicer arietinum (Chickpea) (Garbanzo).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; fabids; Fabales; Fabaceae; Papilionoideae; 50 kb inversion clade;
OC NPAAA clade; Hologalegina; IRL clade; Cicereae; Cicer.
OX NCBI_TaxID=3827 {ECO:0000313|Proteomes:UP000087171, ECO:0000313|RefSeq:XP_004512282.1};
RN [1] {ECO:0000313|RefSeq:XP_004512282.1}
RP IDENTIFICATION.
RC TISSUE=Etiolated seedlings {ECO:0000313|RefSeq:XP_004512282.1};
RG RefSeq;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- FUNCTION: Glutamate-gated receptor that probably acts as non-selective
CC cation channel. {ECO:0000256|PIRNR:PIRNR037090}.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the glutamate-gated ion channel (TC 1.A.10.1)
CC family. {ECO:0000256|ARBA:ARBA00008685, ECO:0000256|PIRNR:PIRNR037090}.
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DR RefSeq; XP_004512282.1; XM_004512225.3.
DR AlphaFoldDB; A0A1S2YZB0; -.
DR GeneID; 101501975; -.
DR OrthoDB; 1011589at2759; -.
DR Proteomes; UP000087171; Chromosome Ca8.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0015276; F:ligand-gated monoatomic ion channel activity; IEA:InterPro.
DR CDD; cd13686; GluR_Plant; 1.
DR CDD; cd19990; PBP1_GABAb_receptor_plant; 1.
DR Gene3D; 1.10.287.70; -; 1.
DR Gene3D; 3.40.50.2300; -; 2.
DR Gene3D; 3.40.190.10; Periplasmic binding protein-like II; 3.
DR InterPro; IPR001828; ANF_lig-bd_rcpt.
DR InterPro; IPR044440; GABAb_receptor_plant_PBP1.
DR InterPro; IPR019594; Glu/Gly-bd.
DR InterPro; IPR015683; Ionotropic_Glu_rcpt.
DR InterPro; IPR001320; Iontro_rcpt_C.
DR InterPro; IPR017103; Iontropic_Glu_rcpt_pln.
DR InterPro; IPR028082; Peripla_BP_I.
DR InterPro; IPR001638; Solute-binding_3/MltF_N.
DR PANTHER; PTHR18966:SF412; GLUTAMATE RECEPTOR 3.6; 1.
DR PANTHER; PTHR18966; IONOTROPIC GLUTAMATE RECEPTOR; 1.
DR Pfam; PF01094; ANF_receptor; 1.
DR Pfam; PF00060; Lig_chan; 1.
DR Pfam; PF10613; Lig_chan-Glu_bd; 1.
DR Pfam; PF00497; SBP_bac_3; 1.
DR PIRSF; PIRSF037090; Iontro_Glu-like_rcpt_pln; 2.
DR SMART; SM00079; PBPe; 1.
DR SUPFAM; SSF53822; Periplasmic binding protein-like I; 1.
DR SUPFAM; SSF53850; Periplasmic binding protein-like II; 1.
PE 3: Inferred from homology;
KW Disulfide bond {ECO:0000256|PIRSR:PIRSR037090-50};
KW Glycoprotein {ECO:0000256|ARBA:ARBA00023180};
KW Ion channel {ECO:0000256|ARBA:ARBA00023303, ECO:0000256|PIRNR:PIRNR037090};
KW Ion transport {ECO:0000256|ARBA:ARBA00023065,
KW ECO:0000256|PIRNR:PIRNR037090};
KW Ligand-gated ion channel {ECO:0000256|ARBA:ARBA00023286,
KW ECO:0000256|PIRNR:PIRNR037090};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|PIRNR:PIRNR037090};
KW Receptor {ECO:0000256|ARBA:ARBA00023170, ECO:0000256|PIRNR:PIRNR037090};
KW Reference proteome {ECO:0000313|Proteomes:UP000087171};
KW Signal {ECO:0000256|ARBA:ARBA00022729, ECO:0000256|SAM:SignalP};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius};
KW Transport {ECO:0000256|ARBA:ARBA00022448, ECO:0000256|PIRNR:PIRNR037090}.
FT SIGNAL 1..21
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 22..915
FT /note="Glutamate receptor"
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5010240782"
FT TRANSMEM 560..578
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 622..646
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 801..823
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 439..780
FT /note="Ionotropic glutamate receptor C-terminal"
FT /evidence="ECO:0000259|SMART:SM00079"
FT DISULFID 729..783
FT /evidence="ECO:0000256|PIRSR:PIRSR037090-50"
SQ SEQUENCE 915 AA; 101144 MW; 834BAE0550577577 CRC64;
MVKIWLLALM ILYNGFSSTE AGIHNSTRPA VVNIGALFSF NTSVGRIIKI AIEAAVKDVN
SDPNILGETK LKLSLQEDSK YRGFLSIAEV LQVMSSDTVA IIGPHSSVTA HVITHIANEL
QVPLLSFSAL DPTLSSLQFP FFIRTCHSDL FQMAAIADLV DYYGWKEVIA VYIDDDNGRN
GITALSDKLA KRRCRISFKA PVSPEATTEE ITNVLVQVAL AESRVIVVHA NTLWGPKVFS
VAKNLGMMTT GYVWIATAFL SAILDISSPL SSDSMDAIQG VLTPRVYIPD SELKRRFVSR
WKNLTYGNTA NGPLGLSFLS FYAYDTVYAL AHALDAFFKQ GNQITFSNDP KLSVLKGVTG
LFKYAPDKNL VNPAYEIINV IGTGSRRIGY WSNHSGLSVV SPEANDSRES QKLFPVIWPG
DTVQKPRGWV FPNNGRLLRI GVPIGVSYRE FVWQVPGTNT FQGFCIDVFL SAVNLLPYAV
PYKFIPYGDG INNPSNTELL RSITAGEFDG AVGDIAITTT RTKLVDFTQP YVESGLVVVA
PVGKTETSAL AFLAPFTPRM WFVTAVFFII VGTVVWILEH RVNDEFRGPP KKQVVTILWF
SFSTMFFSHR ENTVSTLGRC VLLIWLFVVL IITSSYTASL TSILTVQQLS SPIKGIESLV
ISKEPIGYTQ GSFSRSYLIQ EIGIDESRLV PLKTAEEAAR ALEKGPHNGG VAAYVEERAY
IEIFLSSRCE FTVVGQAFTR NGWGFAFPRD SPLAVDLSTA ILQMVDNGDL QRIHDKWLLS
RACLSQGAKL EVEKLKLKSF WGLYAICGSA CLLALFIFLI QIIRQYNKNH SEELDSTDQN
SGSSCLRRFF AFVDKKEETL QNRLKRRKME RISYRSSEGG SSSIIFNKEY VVQPSSCTTG
SVSNGGSEQV SIKVV
//
