ID A0A1S2Z9G8_ERIEU Unreviewed; 378 AA.
AC A0A1S2Z9G8;
DT 12-APR-2017, integrated into UniProtKB/TrEMBL.
DT 12-APR-2017, sequence version 1.
DT 27-MAR-2024, entry version 25.
DE SubName: Full=Ubiquitin-conjugating enzyme E2 variant 3 isoform X4 {ECO:0000313|RefSeq:XP_007515932.1};
GN Name=UEVLD {ECO:0000313|RefSeq:XP_007515932.1};
OS Erinaceus europaeus (Western European hedgehog).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Laurasiatheria; Eulipotyphla; Erinaceidae; Erinaceinae;
OC Erinaceus.
OX NCBI_TaxID=9365 {ECO:0000313|Proteomes:UP000079721, ECO:0000313|RefSeq:XP_007515932.1};
RN [1] {ECO:0000313|RefSeq:XP_007515932.1}
RP IDENTIFICATION.
RG RefSeq;
RL Submitted (NOV-2023) to UniProtKB.
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DR RefSeq; XP_007515932.1; XM_007515870.1.
DR AlphaFoldDB; A0A1S2Z9G8; -.
DR CTD; 55293; -.
DR OrthoDB; 5344346at2759; -.
DR Proteomes; UP000079721; Unplaced.
DR GO; GO:0016616; F:oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor; IEA:InterPro.
DR GO; GO:0019752; P:carboxylic acid metabolic process; IEA:InterPro.
DR GO; GO:0036211; P:protein modification process; IEA:InterPro.
DR GO; GO:0015031; P:protein transport; IEA:InterPro.
DR Gene3D; 3.90.110.10; Lactate dehydrogenase/glycoside hydrolase, family 4, C-terminal; 1.
DR Gene3D; 3.40.50.720; NAD(P)-binding Rossmann-like Domain; 1.
DR Gene3D; 3.10.110.10; Ubiquitin Conjugating Enzyme; 1.
DR InterPro; IPR001557; L-lactate/malate_DH.
DR InterPro; IPR001236; Lactate/malate_DH_N.
DR InterPro; IPR015955; Lactate_DH/Glyco_Ohase_4_C.
DR InterPro; IPR036291; NAD(P)-bd_dom_sf.
DR InterPro; IPR016135; UBQ-conjugating_enzyme/RWD.
DR InterPro; IPR008883; UEV_N.
DR PANTHER; PTHR23306; TUMOR SUSCEPTIBILITY GENE 101 PROTEIN-RELATED; 1.
DR PANTHER; PTHR23306:SF18; UBIQUITIN-CONJUGATING ENZYME E2 VARIANT 3; 1.
DR Pfam; PF00056; Ldh_1_N; 1.
DR Pfam; PF05743; UEV; 1.
DR PRINTS; PR00086; LLDHDRGNASE.
DR SUPFAM; SSF56327; LDH C-terminal domain-like; 1.
DR SUPFAM; SSF51735; NAD(P)-binding Rossmann-fold domains; 1.
DR SUPFAM; SSF54495; UBC-like; 1.
DR PROSITE; PS51322; UEV; 1.
PE 4: Predicted;
KW NAD {ECO:0000256|ARBA:ARBA00023027};
KW Reference proteome {ECO:0000313|Proteomes:UP000079721}.
FT DOMAIN 2..145
FT /note="UEV"
FT /evidence="ECO:0000259|PROSITE:PS51322"
SQ SEQUENCE 378 AA; 42135 MW; 5C8BA074A3A54D20 CRC64;
MDFDCERLRR LLGKYKFRDL TVEELKNVNM IFPHFKYSMD TYVFKDSSQK DLLNFTGTIP
VMYHGTTYNI PIHLWILDSH PFAPPICFLK PTANMGISVG KHVDAQGRIY LPYLQNWSHP
KSVIVGLIKE MIAKFQEELP LYSLSPSDEA RQVDLLAYIA KITEGVSDIN SKNWADQENK
SVSKITVVGG GELGVACTLA ISAKGIVDRL VLLDLSDGTK GGTMDLDIFN LPNVEISKDL
FASAQSKVVI ITVNSLGSSQ SYLDVVQSNV DMFRTLIPAL GHYSQHSVLL VASQPVEIMT
YVTWKLSAFP PSRVIGIGCN LDSQRLQYII TNVLKARISG KEVWVIGEQG EDKVSIWGSQ
EGLSHNSDVQ LSNRDIMM
//
