ID A0A1S2ZBU4_ERIEU Unreviewed; 467 AA.
AC A0A1S2ZBU4;
DT 12-APR-2017, integrated into UniProtKB/TrEMBL.
DT 12-APR-2017, sequence version 1.
DT 27-MAR-2024, entry version 20.
DE SubName: Full=DEP domain-containing protein 1B isoform X3 {ECO:0000313|RefSeq:XP_007516970.1};
GN Name=DEPDC1B {ECO:0000313|RefSeq:XP_007516970.1};
OS Erinaceus europaeus (Western European hedgehog).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Laurasiatheria; Eulipotyphla; Erinaceidae; Erinaceinae;
OC Erinaceus.
OX NCBI_TaxID=9365 {ECO:0000313|Proteomes:UP000079721, ECO:0000313|RefSeq:XP_007516970.1};
RN [1] {ECO:0000313|RefSeq:XP_007516970.1}
RP IDENTIFICATION.
RG RefSeq;
RL Submitted (NOV-2023) to UniProtKB.
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DR RefSeq; XP_007516970.1; XM_007516908.2.
DR AlphaFoldDB; A0A1S2ZBU4; -.
DR CTD; 55789; -.
DR OrthoDB; 5405142at2759; -.
DR Proteomes; UP000079721; Unplaced.
DR GO; GO:0035556; P:intracellular signal transduction; IEA:InterPro.
DR CDD; cd04405; RhoGAP_BRCC3-like; 1.
DR Gene3D; 1.10.555.10; Rho GTPase activation protein; 1.
DR Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 1.
DR InterPro; IPR000591; DEP_dom.
DR InterPro; IPR008936; Rho_GTPase_activation_prot.
DR InterPro; IPR000198; RhoGAP_dom.
DR InterPro; IPR036388; WH-like_DNA-bd_sf.
DR InterPro; IPR036390; WH_DNA-bd_sf.
DR PANTHER; PTHR16206; DEP DOMAIN-CONTAINING; 1.
DR PANTHER; PTHR16206:SF11; DEP DOMAIN-CONTAINING PROTEIN 1B; 1.
DR Pfam; PF00610; DEP; 1.
DR Pfam; PF00620; RhoGAP; 1.
DR SMART; SM00049; DEP; 1.
DR SUPFAM; SSF48350; GTPase activation domain, GAP; 1.
DR SUPFAM; SSF46785; Winged helix' DNA-binding domain; 1.
DR PROSITE; PS50186; DEP; 1.
DR PROSITE; PS50238; RHOGAP; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000079721}.
FT DOMAIN 24..108
FT /note="DEP"
FT /evidence="ECO:0000259|PROSITE:PS50186"
FT DOMAIN 198..393
FT /note="Rho-GAP"
FT /evidence="ECO:0000259|PROSITE:PS50238"
SQ SEQUENCE 467 AA; 54875 MW; 78128232B53BC647 CRC64;
MEHRIVGPGP YRATKLWNET VEHFRHTMPL RKHRCRFKSY DHCFTATEAV DWLHELLRCS
QNFGPEVTRK QTVQLLKKFL KNHVIEDVKG KWGQEDFEDS RHLYRFPPSS PLKPYPKKLP
YQKDIIKFPK WNDPLPGTSQ ENIPVRPLVM NSEMWYKRHS IAIGEVPACR LVHRRQLTEA
NVEEIWKSMT LSYLQKTLGL DSLEEVLDVK HVNSRFIIHN VYSVSKQGVV ILDDKSKELP
HWVLSAMKCL ANWPNCSDLK QPMYLGFEKD VFKTIADYYG HLKEPLLTFH LYDAFVSVLG
LLQKETVAIE AFQLCCLLLP PENRRKLQLL MRMMTRICLN TEMPPLCDGF GARTLMVQTF
SRCILCSKDE VDLDELLAAR LVTFLMDNYQ EILKVPLALQ TSIEERVAHL RRVQFQKSYP
EVYRERFPTP ESEALLFPEK SKPKPQLLTW ALKNPFQPFQ RTRSFRM
//
