ID A0A1S2ZBX8_ERIEU Unreviewed; 92 AA.
AC A0A1S2ZBX8;
DT 12-APR-2017, integrated into UniProtKB/TrEMBL.
DT 12-APR-2017, sequence version 1.
DT 27-MAR-2024, entry version 21.
DE RecName: Full=C-C motif chemokine {ECO:0000256|RuleBase:RU361150};
GN Name=LOC103108093 {ECO:0000313|RefSeq:XP_007517016.1};
OS Erinaceus europaeus (Western European hedgehog).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Laurasiatheria; Eulipotyphla; Erinaceidae; Erinaceinae;
OC Erinaceus.
OX NCBI_TaxID=9365 {ECO:0000313|Proteomes:UP000079721, ECO:0000313|RefSeq:XP_007517016.1};
RN [1] {ECO:0000313|RefSeq:XP_007517016.1}
RP IDENTIFICATION.
RG RefSeq;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Secreted {ECO:0000256|RuleBase:RU361150}.
CC -!- SIMILARITY: Belongs to the intercrine beta (chemokine CC) family.
CC {ECO:0000256|ARBA:ARBA00010868, ECO:0000256|RuleBase:RU361150}.
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DR RefSeq; XP_007517016.1; XM_007516954.2.
DR AlphaFoldDB; A0A1S2ZBX8; -.
DR STRING; 9365.ENSEEUP00000013350; -.
DR GeneID; 103108093; -.
DR eggNOG; ENOG502S8M4; Eukaryota.
DR InParanoid; A0A1S2ZBX8; -.
DR OrthoDB; 4265193at2759; -.
DR Proteomes; UP000079721; Unplaced.
DR GO; GO:0005615; C:extracellular space; IEA:UniProtKB-KW.
DR GO; GO:0008009; F:chemokine activity; IEA:InterPro.
DR GO; GO:0006955; P:immune response; IEA:InterPro.
DR CDD; cd00272; Chemokine_CC; 1.
DR Gene3D; 2.40.50.40; -; 1.
DR InterPro; IPR039809; Chemokine_b/g/d.
DR InterPro; IPR000827; Chemokine_CC_CS.
DR InterPro; IPR001811; Chemokine_IL8-like_dom.
DR InterPro; IPR036048; Interleukin_8-like_sf.
DR PANTHER; PTHR12015:SF103; C-C MOTIF CHEMOKINE 4-RELATED; 1.
DR PANTHER; PTHR12015; SMALL INDUCIBLE CYTOKINE A; 1.
DR Pfam; PF00048; IL8; 1.
DR SMART; SM00199; SCY; 1.
DR SUPFAM; SSF54117; Interleukin 8-like chemokines; 1.
DR PROSITE; PS00472; SMALL_CYTOKINES_CC; 1.
PE 3: Inferred from homology;
KW Chemotaxis {ECO:0000256|RuleBase:RU361150};
KW Cytokine {ECO:0000256|ARBA:ARBA00022514, ECO:0000256|RuleBase:RU361150};
KW Reference proteome {ECO:0000313|Proteomes:UP000079721};
KW Secreted {ECO:0000256|RuleBase:RU361150};
KW Signal {ECO:0000256|RuleBase:RU361150}.
FT SIGNAL 1..23
FT /evidence="ECO:0000256|RuleBase:RU361150"
FT CHAIN 24..92
FT /note="C-C motif chemokine"
FT /evidence="ECO:0000256|RuleBase:RU361150"
FT /id="PRO_5010006940"
FT DOMAIN 31..89
FT /note="Chemokine interleukin-8-like"
FT /evidence="ECO:0000259|SMART:SM00199"
SQ SEQUENCE 92 AA; 10392 MW; 6E826059B8E2851D CRC64;
MKLWVSVLSL LMLMAAFCSP AFSAPIGSDP PTACCFSYTL RKLPRNFVMD YFETSSLCSQ
PAVVFQTKRG RQICANPSEP WVQEYMDDLE LN
//
