ID A0A1S2ZC09_ERIEU Unreviewed; 514 AA.
AC A0A1S2ZC09;
DT 12-APR-2017, integrated into UniProtKB/TrEMBL.
DT 12-APR-2017, sequence version 1.
DT 27-MAR-2024, entry version 28.
DE SubName: Full=Eomesodermin homolog {ECO:0000313|RefSeq:XP_007517051.1};
GN Name=EOMES {ECO:0000313|RefSeq:XP_007517051.1};
OS Erinaceus europaeus (Western European hedgehog).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Laurasiatheria; Eulipotyphla; Erinaceidae; Erinaceinae;
OC Erinaceus.
OX NCBI_TaxID=9365 {ECO:0000313|Proteomes:UP000079721, ECO:0000313|RefSeq:XP_007517051.1};
RN [1] {ECO:0000313|RefSeq:XP_007517051.1}
RP IDENTIFICATION.
RG RefSeq;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|ARBA:ARBA00004123,
CC ECO:0000256|PROSITE-ProRule:PRU00201}.
CC -!- CAUTION: Lacks conserved residue(s) required for the propagation of
CC feature annotation. {ECO:0000256|PROSITE-ProRule:PRU00201}.
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DR RefSeq; XP_007517051.1; XM_007516989.2.
DR AlphaFoldDB; A0A1S2ZC09; -.
DR STRING; 9365.ENSEEUP00000005446; -.
DR GeneID; 103108118; -.
DR CTD; 8320; -.
DR eggNOG; KOG3585; Eukaryota.
DR InParanoid; A0A1S2ZC09; -.
DR OrthoDB; 5323209at2759; -.
DR Proteomes; UP000079721; Unplaced.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0003700; F:DNA-binding transcription factor activity; IEA:InterPro.
DR GO; GO:0000978; F:RNA polymerase II cis-regulatory region sequence-specific DNA binding; IEA:InterPro.
DR GO; GO:0045893; P:positive regulation of DNA-templated transcription; IEA:InterPro.
DR Gene3D; 2.60.40.820; Transcription factor, T-box; 1.
DR InterPro; IPR008967; p53-like_TF_DNA-bd_sf.
DR InterPro; IPR032385; T-box_assoc.
DR InterPro; IPR046360; T-box_DNA-bd.
DR InterPro; IPR036960; T-box_sf.
DR InterPro; IPR001699; TF_T-box.
DR InterPro; IPR018186; TF_T-box_CS.
DR PANTHER; PTHR11267:SF13; EOMESODERMIN HOMOLOG; 1.
DR PANTHER; PTHR11267; T-BOX PROTEIN-RELATED; 1.
DR Pfam; PF00907; T-box; 1.
DR Pfam; PF16176; T-box_assoc; 1.
DR PRINTS; PR00937; TBOX.
DR SMART; SM00425; TBOX; 1.
DR SUPFAM; SSF49417; p53-like transcription factors; 1.
DR PROSITE; PS01283; TBOX_1; 1.
DR PROSITE; PS01264; TBOX_2; 1.
DR PROSITE; PS50252; TBOX_3; 1.
PE 4: Predicted;
KW DNA-binding {ECO:0000256|ARBA:ARBA00023125, ECO:0000256|PROSITE-
KW ProRule:PRU00201};
KW Nucleus {ECO:0000256|ARBA:ARBA00023242, ECO:0000256|PROSITE-
KW ProRule:PRU00201}; Reference proteome {ECO:0000313|Proteomes:UP000079721};
KW Transcription {ECO:0000256|ARBA:ARBA00023163};
KW Transcription regulation {ECO:0000256|ARBA:ARBA00023015}.
FT DOMAIN 80..265
FT /note="T-box"
FT /evidence="ECO:0000259|PROSITE:PS50252"
FT REGION 420..514
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 445..490
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 514 AA; 56235 MW; 39487778AA9F133A CRC64;
MLPPGGFPAA VCPPGRPQFG PGAGAGSGAS GGAGGGPGAY QYSQGAPLYG PYPGAASAGS
CGGLGGLGVP GSGFRAHVYL CNRPLWLKFH RHQTEMIITK QGRRMFPFLS FNINGLNPTA
HYNVFVEVVL ADPNHWRFQG GKWVTCGKAD NNMQGNKMYV HPESPNTGSH WMRQEISFGK
LKLTNNKGAN NNNTQMIVLQ SLHKYQPRLH IVEVTEDGVE DLNEPSKTQT FTFSETQFIA
VTAYQNTDIT QLKIDHNPFA KGFRDNYDSM YTASENDRLT PSPTDSPRSH QIVPGGRYGV
QSFFPEPFVN TLPQARYYNG ERTVPQTNGL LSPQQSEEVA NPPQRWLVTP VQQAGANKLD
IGSYESEYTS STLLPYGIKS LPLQTSHALG YYPDPTFPAM AGWGSRGSYQ RKMAAGLPWA
SRTSPPVFSE DQLSKEKVKE EMSSSWIETP PSIKSLDSND SGVYTSACKR RRLSPSTSSN
ENSPSIKCED INSEEYSKDT SKGMGGYYAF YTTP
//
