ID   A0A1S2ZER7_ERIEU        Unreviewed;       534 AA.
AC   A0A1S2ZER7;
DT   12-APR-2017, integrated into UniProtKB/TrEMBL.
DT   12-APR-2017, sequence version 1.
DT   27-MAR-2024, entry version 28.
DE   SubName: Full=Keratin, type II cytoskeletal 78 {ECO:0000313|RefSeq:XP_007518267.1};
GN   Name=KRT78 {ECO:0000313|RefSeq:XP_007518267.1};
OS   Erinaceus europaeus (Western European hedgehog).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Laurasiatheria; Eulipotyphla; Erinaceidae; Erinaceinae;
OC   Erinaceus.
OX   NCBI_TaxID=9365 {ECO:0000313|Proteomes:UP000079721, ECO:0000313|RefSeq:XP_007518267.1};
RN   [1] {ECO:0000313|RefSeq:XP_007518267.1}
RP   IDENTIFICATION.
RG   RefSeq;
RL   Submitted (NOV-2023) to UniProtKB.
CC   -!- SIMILARITY: Belongs to the intermediate filament family.
CC       {ECO:0000256|RuleBase:RU000685}.
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DR   RefSeq; XP_007518267.1; XM_007518205.1.
DR   AlphaFoldDB; A0A1S2ZER7; -.
DR   STRING; 9365.ENSEEUP00000005536; -.
DR   GeneID; 103109171; -.
DR   CTD; 196374; -.
DR   eggNOG; ENOG502SPJX; Eukaryota.
DR   InParanoid; A0A1S2ZER7; -.
DR   OrthoDB; 4640531at2759; -.
DR   Proteomes; UP000079721; Unplaced.
DR   GO; GO:0045095; C:keratin filament; IEA:InterPro.
DR   Gene3D; 1.20.5.170; -; 1.
DR   Gene3D; 1.20.5.500; Single helix bin; 1.
DR   Gene3D; 1.20.5.1160; Vasodilator-stimulated phosphoprotein; 1.
DR   InterPro; IPR018039; IF_conserved.
DR   InterPro; IPR039008; IF_rod_dom.
DR   InterPro; IPR032444; Keratin_2_head.
DR   InterPro; IPR003054; Keratin_II.
DR   PANTHER; PTHR45616; GATA-TYPE DOMAIN-CONTAINING PROTEIN; 1.
DR   PANTHER; PTHR45616:SF18; KERATIN, TYPE II CYTOSKELETAL 78; 1.
DR   Pfam; PF00038; Filament; 1.
DR   Pfam; PF16208; Keratin_2_head; 1.
DR   PRINTS; PR01276; TYPE2KERATIN.
DR   SMART; SM01391; Filament; 1.
DR   SUPFAM; SSF64593; Intermediate filament protein, coiled coil region; 2.
DR   PROSITE; PS00226; IF_ROD_1; 1.
DR   PROSITE; PS51842; IF_ROD_2; 1.
PE   3: Inferred from homology;
KW   Coiled coil {ECO:0000256|ARBA:ARBA00023054, ECO:0000256|SAM:Coils};
KW   Intermediate filament {ECO:0000256|ARBA:ARBA00022754,
KW   ECO:0000256|RuleBase:RU000685}; Keratin {ECO:0000256|ARBA:ARBA00022744};
KW   Reference proteome {ECO:0000313|Proteomes:UP000079721}.
FT   DOMAIN          105..418
FT                   /note="IF rod"
FT                   /evidence="ECO:0000259|PROSITE:PS51842"
FT   REGION          47..70
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COILED          160..201
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          316..396
FT                   /evidence="ECO:0000256|SAM:Coils"
SQ   SEQUENCE   534 AA;  57791 MW;  9FF1FCF50695B473 CRC64;
     MSASPLRAQR GFSALSACST HPRGNSWGGF SSRSFTSSRG CRAATRGRTL GAGGRQGLQS
     GGAHGGSGPS LCPAGGIQEV TINQSLLTPL KIEIDPQFQA VRTQETSEIR TLNNQFASFI
     DKVRFLEQQN KFLETKWALI QQQGQSHGPR NLESYFESYL AQLRRRLEEL QRDRGALDAE
     LKSCQDQEEE YKAKFEQEAQ RRTTVENDFV VLKKDTDEVF LRKMELEDQL ESLRVHTCFL
     RRLYEEELGQ LRTQAGDMSV VLSMDNNRCL DFSDLIADIR ARYEEVTQTS KAEAETLFKT
     KYQELQESAQ LQGDNIKASK IQITQLQQAI QRLQSQMENL KKQNASLQAS VTDAEQRGEL
     ALKDARAKLE ELEAALKAAK QDMAQLLRDY QELMCTKLAL DVEIATYRRL LEGEESRMSG
     ACTSQVTISV SGGSAGVSGG AVGGPGGPGG TCGLGGGRGH FGPSCFSIVT GCSSVVTGGS
     SAFMGSGQGS GKGSLLGSCS VSGSGLGSGS SSSSVCHTIL KKTVESSLKT SVTY
//