ID A0A1S2ZHA8_ERIEU Unreviewed; 285 AA.
AC A0A1S2ZHA8;
DT 12-APR-2017, integrated into UniProtKB/TrEMBL.
DT 12-APR-2017, sequence version 1.
DT 27-MAR-2024, entry version 28.
DE SubName: Full=Meiotic recombination protein DMC1/LIM15 homolog isoform X2 {ECO:0000313|RefSeq:XP_007519376.1};
GN Name=DMC1 {ECO:0000313|RefSeq:XP_007519376.1};
OS Erinaceus europaeus (Western European hedgehog).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Laurasiatheria; Eulipotyphla; Erinaceidae; Erinaceinae;
OC Erinaceus.
OX NCBI_TaxID=9365 {ECO:0000313|Proteomes:UP000079721, ECO:0000313|RefSeq:XP_007519376.1};
RN [1] {ECO:0000313|RefSeq:XP_007519376.1}
RP IDENTIFICATION.
RG RefSeq;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Chromosome {ECO:0000256|ARBA:ARBA00004286}.
CC Nucleus {ECO:0000256|ARBA:ARBA00004123}.
CC -!- SIMILARITY: Belongs to the RecA family.
CC {ECO:0000256|RuleBase:RU003422}.
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DR RefSeq; XP_007519376.1; XM_007519314.2.
DR AlphaFoldDB; A0A1S2ZHA8; -.
DR CTD; 11144; -.
DR OrthoDB; 5477610at2759; -.
DR Proteomes; UP000079721; Unplaced.
DR GO; GO:0005694; C:chromosome; IEA:UniProtKB-SubCell.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-KW.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0140664; F:ATP-dependent DNA damage sensor activity; IEA:InterPro.
DR GO; GO:0003677; F:DNA binding; IEA:InterPro.
DR GO; GO:0006281; P:DNA repair; IEA:InterPro.
DR Gene3D; 1.10.150.20; 5' to 3' exonuclease, C-terminal subdomain; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 2.
DR InterPro; IPR013632; DNA_recomb/repair_Rad51_C.
DR InterPro; IPR016467; DNA_recomb/repair_RecA-like.
DR InterPro; IPR010995; DNA_repair_Rad51/TF_NusA_a-hlx.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR020588; RecA_ATP-bd.
DR InterPro; IPR020587; RecA_monomer-monomer_interface.
DR PANTHER; PTHR22942:SF30; MEIOTIC RECOMBINATION PROTEIN DMC1_LIM15 HOMOLOG; 1.
DR PANTHER; PTHR22942; RECA/RAD51/RADA DNA STRAND-PAIRING FAMILY MEMBER; 1.
DR Pfam; PF14520; HHH_5; 1.
DR Pfam; PF08423; Rad51; 2.
DR PIRSF; PIRSF005856; Rad51; 2.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR SUPFAM; SSF47794; Rad51 N-terminal domain-like; 1.
DR PROSITE; PS50162; RECA_2; 1.
DR PROSITE; PS50163; RECA_3; 1.
PE 3: Inferred from homology;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840, ECO:0000256|RuleBase:RU003422};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741,
KW ECO:0000256|RuleBase:RU003422};
KW Reference proteome {ECO:0000313|Proteomes:UP000079721}.
FT DOMAIN 163..215
FT /note="RecA family profile 1"
FT /evidence="ECO:0000259|PROSITE:PS50162"
FT DOMAIN 222..285
FT /note="RecA family profile 2"
FT /evidence="ECO:0000259|PROSITE:PS50163"
SQ SEQUENCE 285 AA; 31563 MW; 25AD3BE9E71FC5FC CRC64;
MKEDQVVLEE SGFQEDEESL FQDIDLLQKH GINVADIKKL KSVGICTVKG IQMTTRRALC
NVKGLSEAKV DKIKEAANKL IEPGFLTAFE YSEKRKMVFH ITTGSQEFDK LLGGGIESMA
ITEAFGEFRT GKTQLSHTLC GEHQMELLDY VAAKFHEEAG IFKLLIIDSI MALFRVDFSG
RGELAERQQK LAQMLSRLQK ISEEYNVAVF VTNQMTADPG ATMTFQADPK KPIGGHILAH
ASTTRISLRK GRGELRIAKI YDSPDMPENE ATFAITAGGI GDAKE
//
