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Database: UniProt
Entry: A0A1S2ZHY6_ERIEU
LinkDB: A0A1S2ZHY6_ERIEU
Original site: A0A1S2ZHY6_ERIEU 
ID   A0A1S2ZHY6_ERIEU        Unreviewed;       360 AA.
AC   A0A1S2ZHY6;
DT   12-APR-2017, integrated into UniProtKB/TrEMBL.
DT   12-APR-2017, sequence version 1.
DT   05-JUN-2019, entry version 13.
DE   SubName: Full=inward rectifier potassium channel 13 isoform X1 {ECO:0000313|RefSeq:XP_007519630.1, ECO:0000313|RefSeq:XP_007519636.1};
GN   Name=KCNJ13 {ECO:0000313|RefSeq:XP_007519630.1,
GN   ECO:0000313|RefSeq:XP_007519636.1};
OS   Erinaceus europaeus (Western European hedgehog).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Mammalia; Eutheria; Laurasiatheria; Eulipotyphla; Erinaceidae;
OC   Erinaceinae; Erinaceus.
OX   NCBI_TaxID=9365 {ECO:0000313|Proteomes:UP000079721, ECO:0000313|RefSeq:XP_007519636.1};
RN   [1] {ECO:0000313|RefSeq:XP_007519630.1, ECO:0000313|RefSeq:XP_007519636.1}
RP   IDENTIFICATION.
RG   RefSeq;
RL   Submitted (FEB-2017) to UniProtKB.
CC   -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|RuleBase:RU003822};
CC       Multi-pass membrane protein {ECO:0000256|RuleBase:RU003822}.
CC   -!- SIMILARITY: Belongs to the inward rectifier-type potassium channel
CC       (TC 1.A.2.1) family. {ECO:0000256|RuleBase:RU003822,
CC       ECO:0000256|SAAS:SAAS00549381}.
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DR   RefSeq; XP_007519630.1; XM_007519568.1.
DR   RefSeq; XP_007519636.1; XM_007519574.1.
DR   STRING; 9365.XP_007519630.1; -.
DR   GeneID; 103110393; -.
DR   CTD; 3769; -.
DR   OrthoDB; 956263at2759; -.
DR   Proteomes; UP000079721; Genome assembly.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0005242; F:inward rectifier potassium channel activity; IEA:InterPro.
DR   GO; GO:0034765; P:regulation of ion transmembrane transport; IEA:UniProtKB-KW.
DR   Gene3D; 2.60.40.1400; -; 1.
DR   InterPro; IPR014756; Ig_E-set.
DR   InterPro; IPR041647; IRK_C.
DR   InterPro; IPR016449; K_chnl_inward-rec_Kir.
DR   InterPro; IPR013518; K_chnl_inward-rec_Kir_cyto.
DR   InterPro; IPR008062; KCNJ13.
DR   InterPro; IPR040445; Kir_TM.
DR   PANTHER; PTHR11767; PTHR11767; 1.
DR   PANTHER; PTHR11767:SF3; PTHR11767:SF3; 1.
DR   Pfam; PF01007; IRK; 1.
DR   Pfam; PF17655; IRK_C; 1.
DR   PIRSF; PIRSF005465; GIRK_kir; 1.
DR   PRINTS; PR01679; KIR7CHANNEL.
DR   PRINTS; PR01320; KIRCHANNEL.
DR   SUPFAM; SSF81296; SSF81296; 1.
PE   3: Inferred from homology;
KW   Complete proteome {ECO:0000313|Proteomes:UP000079721};
KW   Ion channel {ECO:0000256|RuleBase:RU003822,
KW   ECO:0000256|SAAS:SAAS00434609, ECO:0000313|RefSeq:XP_007519630.1,
KW   ECO:0000313|RefSeq:XP_007519636.1};
KW   Ion transport {ECO:0000256|RuleBase:RU003822,
KW   ECO:0000256|SAAS:SAAS00434639};
KW   Membrane {ECO:0000256|SAAS:SAAS00434581, ECO:0000256|SAM:Phobius};
KW   Potassium {ECO:0000256|RuleBase:RU003822,
KW   ECO:0000256|SAAS:SAAS00434575};
KW   Potassium transport {ECO:0000256|RuleBase:RU003822,
KW   ECO:0000256|SAAS:SAAS00434641};
KW   Reference proteome {ECO:0000313|Proteomes:UP000079721};
KW   Transmembrane {ECO:0000256|RuleBase:RU003822,
KW   ECO:0000256|SAAS:SAAS00434543, ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAAS:SAAS00036756,
KW   ECO:0000256|SAM:Phobius};
KW   Transport {ECO:0000256|RuleBase:RU003822,
KW   ECO:0000256|SAAS:SAAS00036755};
KW   Voltage-gated channel {ECO:0000256|RuleBase:RU003822,
KW   ECO:0000256|SAAS:SAAS00048561}.
FT   TRANSMEM     55     78       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM    134    158       Helical. {ECO:0000256|SAM:Phobius}.
FT   DOMAIN       21    163       IRK. {ECO:0000259|Pfam:PF01007}.
FT   DOMAIN      170    332       IRK_C. {ECO:0000259|Pfam:PF17655}.
FT   SITE        149    149       Role in the control of polyamine-mediated
FT                                channel gating and in the blocking by
FT                                intracellular magnesium.
FT                                {ECO:0000256|PIRSR:PIRSR005465-1}.
SQ   SEQUENCE   360 AA;  40570 MW;  BBB16A671C97B09F CRC64;
     MDGSNCKVIA PLLTQRYRRM VTKDGHSTLQ MDGAQRGLAY LRDAWGILMD MRWRWMMLVF
     SASFVVHWLV FAVLWYVLAE MNGDLELDHD SPPENHTICV KYITSFTAAF SFSLETQLTI
     GYGTMFPSGD CPSAIALLAI QMLLGLMLEA FITGAFVAKI ARPKNRAFSI RFTDLAVVAH
     IDGKPNLIFQ VANTRPSPLT SVRVSAILYQ ERENGELYQT SVDFHLDGIS SEECPFFIFP
     LTYYHSIIPS SPLATLLQRE NPPHFELVVF LSAMQEGTGE ICQRRTSYLP SEIMLHHCFA
     SLLTRGPKGE YQIKMENFDK TVPELPTPLV SKSPNRTDLD IHINGQSIDN FQISETGLTE
//
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