ID A0A1S2ZI99_ERIEU Unreviewed; 346 AA.
AC A0A1S2ZI99;
DT 12-APR-2017, integrated into UniProtKB/TrEMBL.
DT 12-APR-2017, sequence version 1.
DT 27-MAR-2024, entry version 23.
DE SubName: Full=Interleukin-10 receptor subunit beta {ECO:0000313|RefSeq:XP_007519798.1};
GN Name=IL10RB {ECO:0000313|RefSeq:XP_007519798.1};
OS Erinaceus europaeus (Western European hedgehog).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Laurasiatheria; Eulipotyphla; Erinaceidae; Erinaceinae;
OC Erinaceus.
OX NCBI_TaxID=9365 {ECO:0000313|Proteomes:UP000079721, ECO:0000313|RefSeq:XP_007519798.1};
RN [1] {ECO:0000313|RefSeq:XP_007519798.1}
RP IDENTIFICATION.
RG RefSeq;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004479}; Single-
CC pass type I membrane protein {ECO:0000256|ARBA:ARBA00004479}.
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DR RefSeq; XP_007519798.1; XM_007519736.2.
DR AlphaFoldDB; A0A1S2ZI99; -.
DR GeneID; 103110570; -.
DR CTD; 3588; -.
DR eggNOG; ENOG502S2QA; Eukaryota.
DR InParanoid; A0A1S2ZI99; -.
DR OrthoDB; 4004685at2759; -.
DR Proteomes; UP000079721; Unplaced.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR Gene3D; 2.60.40.10; Immunoglobulins; 2.
DR InterPro; IPR003961; FN3_dom.
DR InterPro; IPR036116; FN3_sf.
DR InterPro; IPR013783; Ig-like_fold.
DR InterPro; IPR015373; Interferon/interleukin_rcp_dom.
DR PANTHER; PTHR20859; INTERFERON/INTERLEUKIN RECEPTOR; 1.
DR PANTHER; PTHR20859:SF50; INTERLEUKIN-10 RECEPTOR SUBUNIT BETA; 1.
DR Pfam; PF09294; Interfer-bind; 1.
DR Pfam; PF01108; Tissue_fac; 1.
DR SMART; SM00060; FN3; 2.
DR SUPFAM; SSF49265; Fibronectin type III; 2.
DR PROSITE; PS50853; FN3; 2.
PE 4: Predicted;
KW Membrane {ECO:0000256|SAM:Phobius};
KW Receptor {ECO:0000313|RefSeq:XP_007519798.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000079721};
KW Signal {ECO:0000256|SAM:SignalP}; Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT SIGNAL 1..19
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 20..346
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5010342460"
FT TRANSMEM 221..249
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 23..111
FT /note="Fibronectin type-III"
FT /evidence="ECO:0000259|PROSITE:PS50853"
FT DOMAIN 114..215
FT /note="Fibronectin type-III"
FT /evidence="ECO:0000259|PROSITE:PS50853"
FT REGION 304..346
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 346 AA; 38816 MW; AD8863594F43A9C3 CRC64;
MARILETWLG CCLLVSAFGM VPPPENIRVN SVNFKSLLQW DTPALPQGNL TFTVQFLSYQ
KFQDMCTNTK KTECNFSSLS KYGEHTLRVR TESEGNHSIW VNVTFCPVEE TLIGPVGMQV
NALSESLYIH LSSPQVENEP EGWTLKSVYS AWAYHVLYWK NGSDGKIPLM SQHDSLVLQN
LEPWTTYCVQ AQAFVSDRNK TGKWNEPVCE QTAEDGTLPS WLIPLLVFGA SFCVALLLFC
CVVLLWGVYR KTKYALWPRS VLPQHLTEFW SHPHHNTLLF FPLSEESEVF DKLSVVTQLC
PASKQGVGDS GHQAAPEGAD SGEHHSPLLP TPASESYWTG REAEAT
//
