ID A0A1S2ZKI3_ERIEU Unreviewed; 606 AA.
AC A0A1S2ZKI3;
DT 12-APR-2017, integrated into UniProtKB/TrEMBL.
DT 12-APR-2017, sequence version 1.
DT 27-MAR-2024, entry version 33.
DE SubName: Full=Baculoviral IAP repeat-containing protein 2 {ECO:0000313|RefSeq:XP_007520788.1};
GN Name=LOC103111441 {ECO:0000313|RefSeq:XP_007520788.1};
OS Erinaceus europaeus (Western European hedgehog).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Laurasiatheria; Eulipotyphla; Erinaceidae; Erinaceinae;
OC Erinaceus.
OX NCBI_TaxID=9365 {ECO:0000313|Proteomes:UP000079721, ECO:0000313|RefSeq:XP_007520788.1};
RN [1] {ECO:0000313|RefSeq:XP_007520788.1}
RP IDENTIFICATION.
RG RefSeq;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SIMILARITY: Belongs to the IAP family. {ECO:0000256|ARBA:ARBA00006672}.
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DR RefSeq; XP_007520788.1; XM_007520726.2.
DR AlphaFoldDB; A0A1S2ZKI3; -.
DR STRING; 9365.ENSEEUP00000007560; -.
DR GeneID; 103111441; -.
DR eggNOG; KOG1101; Eukaryota.
DR InParanoid; A0A1S2ZKI3; -.
DR OrthoDB; 383715at2759; -.
DR Proteomes; UP000079721; Unplaced.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR GO; GO:0031398; P:positive regulation of protein ubiquitination; IEA:UniProt.
DR GO; GO:0042981; P:regulation of apoptotic process; IEA:InterPro.
DR CDD; cd00022; BIR; 3.
DR CDD; cd08329; CARD_BIRC2_BIRC3; 1.
DR CDD; cd16713; RING-HC_BIRC2_3_7; 1.
DR CDD; cd14394; UBA_BIRC2_3; 1.
DR Gene3D; 1.10.533.10; Death Domain, Fas; 1.
DR Gene3D; 1.10.8.10; DNA helicase RuvA subunit, C-terminal domain; 1.
DR InterPro; IPR001370; BIR_rpt.
DR InterPro; IPR048875; BIRC2-3-like_UBA.
DR InterPro; IPR041933; BIRC2/BIRC3_UBA.
DR InterPro; IPR001315; CARD.
DR InterPro; IPR011029; DEATH-like_dom_sf.
DR InterPro; IPR001841; Znf_RING.
DR PANTHER; PTHR10044:SF79; BACULOVIRAL IAP REPEAT-CONTAINING PROTEIN 2; 1.
DR PANTHER; PTHR10044; INHIBITOR OF APOPTOSIS; 1.
DR Pfam; PF00653; BIR; 3.
DR Pfam; PF21290; BIRC2-3-like_UBA; 1.
DR Pfam; PF00619; CARD; 1.
DR Pfam; PF13920; zf-C3HC4_3; 1.
DR SMART; SM00238; BIR; 3.
DR SMART; SM00114; CARD; 1.
DR SMART; SM00184; RING; 1.
DR SUPFAM; SSF47986; DEATH domain; 1.
DR SUPFAM; SSF57924; Inhibitor of apoptosis (IAP) repeat; 3.
DR PROSITE; PS01282; BIR_REPEAT_1; 2.
DR PROSITE; PS50143; BIR_REPEAT_2; 3.
DR PROSITE; PS50209; CARD; 1.
DR PROSITE; PS50089; ZF_RING_2; 1.
PE 3: Inferred from homology;
KW Coiled coil {ECO:0000256|SAM:Coils};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Reference proteome {ECO:0000313|Proteomes:UP000079721};
KW Zinc {ECO:0000256|ARBA:ARBA00022833};
KW Zinc-finger {ECO:0000256|ARBA:ARBA00022771, ECO:0000256|PROSITE-
KW ProRule:PRU00175}.
FT DOMAIN 441..531
FT /note="CARD"
FT /evidence="ECO:0000259|PROSITE:PS50209"
FT DOMAIN 559..594
FT /note="RING-type"
FT /evidence="ECO:0000259|PROSITE:PS50089"
FT REGION 105..144
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 415..444
FT /evidence="ECO:0000256|SAM:Coils"
SQ SEQUENCE 606 AA; 68146 MW; C282CD49DB8C47B5 CRC64;
MMEGSTILSN CSSDNKQNMK YDFSCELYRM STYSAFPAGV PVSERSLARA GFYYTGVFDK
VKCFCCGLML DNWKQGDSPA EKHRRLYPSC SFIKNLVSVS NLNSTSNLDS TSKNTSPVRN
SFKHSLCSPT SESGGSPSGS YSSLSLNPAH SRAVDDSSPL RTDLYSYAMS TEEARILTYH
RWPLTFLTPA ELARAGFYYL GPGDRVACFA CAGTLSNWEP KDDAMSEHRR YFPNCPFLEY
SLETLRFSIS NLSMQTHAAR LRTFMCWPSS VPVRPEQLAS AGFYCVGRND DVKCFCCDGG
LRCWESGDDP WVEHAKWFPR CEFLIRMKGQ DFVDEIQARY PHLLEQLLST SDTSGDENPD
PPIVHLRPGE SSSDDAVMMN TPVVKAALEM GFNRNLVKQT VQSQILTTGE NFKTVNDIVS
ALLNAEDEKR EEEKERQIEE VASDDLSLIR RNRMALFQQL TCVLPILDNL LKASVINKQE
HEIIKQKTQI PLQARELIDT VLVKGNAAAN IFKNCLKEID SALYKALFVE NNMKYIPSED
VSGLSLQEQL RRLQEERTCK VCMDKEVSVV FIPCGHLVVC QECAPSLRKC PICRGIIKGT
VRTFLS
//
