GenomeNet

Database: UniProt
Entry: A0A1S2ZKW3_ERIEU
LinkDB: A0A1S2ZKW3_ERIEU
Original site: A0A1S2ZKW3_ERIEU 
ID   A0A1S2ZKW3_ERIEU        Unreviewed;       500 AA.
AC   A0A1S2ZKW3;
DT   12-APR-2017, integrated into UniProtKB/TrEMBL.
DT   12-APR-2017, sequence version 1.
DT   08-MAY-2019, entry version 11.
DE   SubName: Full=G protein-activated inward rectifier potassium channel 1 isoform X1 {ECO:0000313|RefSeq:XP_007520942.1};
GN   Name=KCNJ3 {ECO:0000313|RefSeq:XP_007520942.1};
OS   Erinaceus europaeus (Western European hedgehog).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Mammalia; Eutheria; Laurasiatheria; Eulipotyphla; Erinaceidae;
OC   Erinaceinae; Erinaceus.
OX   NCBI_TaxID=9365 {ECO:0000313|Proteomes:UP000079721, ECO:0000313|RefSeq:XP_007520942.1};
RN   [1] {ECO:0000313|RefSeq:XP_007520942.1}
RP   IDENTIFICATION.
RG   RefSeq;
RL   Submitted (FEB-2017) to UniProtKB.
CC   -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|RuleBase:RU003822};
CC       Multi-pass membrane protein {ECO:0000256|RuleBase:RU003822}.
CC   -!- SIMILARITY: Belongs to the inward rectifier-type potassium channel
CC       (TC 1.A.2.1) family. {ECO:0000256|RuleBase:RU003822,
CC       ECO:0000256|SAAS:SAAS00549381}.
CC   -----------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   -----------------------------------------------------------------------
DR   RefSeq; XP_007520942.1; XM_007520880.1.
DR   STRING; 9365.XP_007520942.1; -.
DR   GeneID; 103111586; -.
DR   CTD; 3760; -.
DR   OrthoDB; 956263at2759; -.
DR   Proteomes; UP000079721; Genome assembly.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0015467; F:G-protein activated inward rectifier potassium channel activity; IEA:InterPro.
DR   GO; GO:0034765; P:regulation of ion transmembrane transport; IEA:UniProtKB-KW.
DR   Gene3D; 2.60.40.1400; -; 1.
DR   InterPro; IPR014756; Ig_E-set.
DR   InterPro; IPR041647; IRK_C.
DR   InterPro; IPR016449; K_chnl_inward-rec_Kir.
DR   InterPro; IPR003274; K_chnl_inward-rec_Kir3.1.
DR   InterPro; IPR013518; K_chnl_inward-rec_Kir_cyto.
DR   InterPro; IPR040445; Kir_TM.
DR   PANTHER; PTHR11767; PTHR11767; 1.
DR   Pfam; PF01007; IRK; 1.
DR   Pfam; PF17655; IRK_C; 1.
DR   PRINTS; PR01327; KIR31CHANNEL.
DR   PRINTS; PR01320; KIRCHANNEL.
DR   SUPFAM; SSF81296; SSF81296; 1.
PE   3: Inferred from homology;
KW   Complete proteome {ECO:0000313|Proteomes:UP000079721};
KW   Ion channel {ECO:0000256|RuleBase:RU003822,
KW   ECO:0000256|SAAS:SAAS00434609, ECO:0000313|RefSeq:XP_007520942.1};
KW   Ion transport {ECO:0000256|RuleBase:RU003822,
KW   ECO:0000256|SAAS:SAAS00434639};
KW   Membrane {ECO:0000256|SAAS:SAAS00434581, ECO:0000256|SAM:Phobius};
KW   Potassium {ECO:0000256|RuleBase:RU003822,
KW   ECO:0000256|SAAS:SAAS00434575};
KW   Potassium transport {ECO:0000256|RuleBase:RU003822,
KW   ECO:0000256|SAAS:SAAS00434641};
KW   Reference proteome {ECO:0000313|Proteomes:UP000079721};
KW   Transmembrane {ECO:0000256|RuleBase:RU003822,
KW   ECO:0000256|SAAS:SAAS00434543, ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAAS:SAAS00036756,
KW   ECO:0000256|SAM:Phobius};
KW   Transport {ECO:0000256|RuleBase:RU003822,
KW   ECO:0000256|SAAS:SAAS00036755};
KW   Voltage-gated channel {ECO:0000256|RuleBase:RU003822,
KW   ECO:0000256|SAAS:SAAS00048561}.
FT   TRANSMEM     83    104       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM    158    181       Helical. {ECO:0000256|SAM:Phobius}.
FT   DOMAIN       46    186       IRK. {ECO:0000259|Pfam:PF01007}.
FT   DOMAIN      193    363       IRK_C. {ECO:0000259|Pfam:PF17655}.
SQ   SEQUENCE   500 AA;  56411 MW;  E702AC2867CDE584 CRC64;
     MSAIRRKFGD DYQVVTTSSS GAGLQPQGPG QGAQQLVPKK KRQRFVDKNG RCNVQHGNLG
     SETSRYLSDL FTTLVDLKWR WNLFIFILTY TVAWLFMASM WWVIAYTRGD LNKAHVGNYT
     PCVANVYNFP SAFLFFIETE ATIGYGYRYI TDKCPEGIIL FLFQSILGSI VDAFLIGCMF
     IKMSQPKKRA ETLMFSEHAV ISMRDGKLTL MFRVGNLRNS HMVSAQIRCK LLKSRQTPEG
     EFLPLDQLEL DVGFSTGADQ LFLVSPLTIC HVIDAKSPFY DLSQRSMQTE QFEIVVILEG
     IVETTGMTCQ ARTSYTEDEV LWGHRFFPVI SLEEGFFKVD YSQFHATFEV PTPPYSVKEQ
     EEMLLMSSPL IAPAITNSKE RHNSVECLDG LDDMSTKLPS KLQKITGRED FPKKLLRMSS
     TTSEKAYSLG DLPMKLQRIS SVPGNSEEKL ASKTTKMLSD PMSQSMADLP PKLQKMAGGA
     VRMEGNLPAK LRKMNSDRFT
//
DBGET integrated database retrieval system