ID A0A1S2ZMZ5_ERIEU Unreviewed; 313 AA.
AC A0A1S2ZMZ5;
DT 12-APR-2017, integrated into UniProtKB/TrEMBL.
DT 12-APR-2017, sequence version 1.
DT 27-MAR-2024, entry version 23.
DE SubName: Full=Cytoplasmic protein NCK1 isoform X2 {ECO:0000313|RefSeq:XP_007521864.1};
GN Name=NCK1 {ECO:0000313|RefSeq:XP_007521864.1};
OS Erinaceus europaeus (Western European hedgehog).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Laurasiatheria; Eulipotyphla; Erinaceidae; Erinaceinae;
OC Erinaceus.
OX NCBI_TaxID=9365 {ECO:0000313|Proteomes:UP000079721, ECO:0000313|RefSeq:XP_007521864.1};
RN [1] {ECO:0000313|RefSeq:XP_007521864.1}
RP IDENTIFICATION.
RG RefSeq;
RL Submitted (NOV-2023) to UniProtKB.
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DR RefSeq; XP_007521864.1; XM_007521802.2.
DR AlphaFoldDB; A0A1S2ZMZ5; -.
DR GeneID; 103112381; -.
DR CTD; 4690; -.
DR OrthoDB; 25798at2759; -.
DR Proteomes; UP000079721; Unplaced.
DR CDD; cd10408; SH2_Nck1; 1.
DR CDD; cd11901; SH3_Nck1_2; 1.
DR CDD; cd11904; SH3_Nck1_3; 1.
DR Gene3D; 3.30.505.10; SH2 domain; 1.
DR Gene3D; 2.30.30.40; SH3 Domains; 2.
DR InterPro; IPR017304; NCK.
DR InterPro; IPR035882; Nck1_SH2.
DR InterPro; IPR035564; Nck1_SH3_2.
DR InterPro; IPR035565; Nck1_SH3_3.
DR InterPro; IPR000980; SH2.
DR InterPro; IPR036860; SH2_dom_sf.
DR InterPro; IPR036028; SH3-like_dom_sf.
DR InterPro; IPR001452; SH3_domain.
DR PANTHER; PTHR19969:SF16; CYTOPLASMIC PROTEIN NCK1; 1.
DR PANTHER; PTHR19969; SH2-SH3 ADAPTOR PROTEIN-RELATED; 1.
DR Pfam; PF00017; SH2; 1.
DR Pfam; PF00018; SH3_1; 2.
DR PIRSF; PIRSF037874; Cytoplasmic_NCK; 1.
DR PRINTS; PR00401; SH2DOMAIN.
DR PRINTS; PR00452; SH3DOMAIN.
DR SMART; SM00252; SH2; 1.
DR SMART; SM00326; SH3; 2.
DR SUPFAM; SSF55550; SH2 domain; 1.
DR SUPFAM; SSF50044; SH3-domain; 2.
DR PROSITE; PS50001; SH2; 1.
DR PROSITE; PS50002; SH3; 2.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000079721};
KW SH2 domain {ECO:0000256|PROSITE-ProRule:PRU00191};
KW SH3 domain {ECO:0000256|ARBA:ARBA00022443, ECO:0000256|PROSITE-
KW ProRule:PRU00192}.
FT DOMAIN 42..101
FT /note="SH3"
FT /evidence="ECO:0000259|PROSITE:PS50002"
FT DOMAIN 126..188
FT /note="SH3"
FT /evidence="ECO:0000259|PROSITE:PS50002"
FT DOMAIN 218..310
FT /note="SH2"
FT /evidence="ECO:0000259|PROSITE:PS50001"
SQ SEQUENCE 313 AA; 35558 MW; 345060D5D5D038FC CRC64;
MDWLNVFKDF FSIGKVKRKP SVPDSASTAE DSFVDPGERL YDLNMPAYVK FNYMAEREDE
LSLIKGTKVI VMEKCSDGWW RGSYNGQVGW FPSNYVTEEG DSPLGDHVGS LSEKLAAVVN
NLSTGQVLHV VQALYPFSSS NDEELNFEKG DVMDVIEKPE NDPEWWKCRK INGMVGLVPK
NYVTIMQTNP LNSGLEPSPP QCDYIRPSLT GRFAGNPWYY GKVTRHQAEM ALNERGHEGD
FLIRDSESSP NDFSVSLKAQ GKNKHFKVQL KETVYCIGQR KFSTMEELVE HYKKAPIFTS
EQGEKLYLIK HLS
//
