ID A0A1S2ZQ94_ERIEU Unreviewed; 335 AA.
AC A0A1S2ZQ94;
DT 12-APR-2017, integrated into UniProtKB/TrEMBL.
DT 12-APR-2017, sequence version 1.
DT 27-MAR-2024, entry version 25.
DE SubName: Full=Rho guanine nucleotide exchange factor 39 {ECO:0000313|RefSeq:XP_007522883.2, ECO:0000313|RefSeq:XP_007522955.1};
GN Name=ARHGEF39 {ECO:0000313|RefSeq:XP_007522883.2};
GN Synonyms=LOC103113360 {ECO:0000313|RefSeq:XP_007522955.1};
OS Erinaceus europaeus (Western European hedgehog).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Laurasiatheria; Eulipotyphla; Erinaceidae; Erinaceinae;
OC Erinaceus.
OX NCBI_TaxID=9365 {ECO:0000313|Proteomes:UP000079721, ECO:0000313|RefSeq:XP_007522883.2};
RN [1] {ECO:0000313|RefSeq:XP_007522883.2, ECO:0000313|RefSeq:XP_007522955.1}
RP IDENTIFICATION.
RG RefSeq;
RL Submitted (NOV-2023) to UniProtKB.
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DR RefSeq; XP_007522883.2; XM_007522821.2.
DR RefSeq; XP_007522955.1; XM_007522893.2.
DR GeneID; 103113360; -.
DR CTD; 84904; -.
DR eggNOG; ENOG502QTR5; Eukaryota.
DR OrthoDB; 4633688at2759; -.
DR Proteomes; UP000079721; Unplaced.
DR GO; GO:0005085; F:guanyl-nucleotide exchange factor activity; IEA:InterPro.
DR Gene3D; 1.20.900.10; Dbl homology (DH) domain; 1.
DR Gene3D; 2.30.29.30; Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB); 1.
DR InterPro; IPR042987; ARHGEF39.
DR InterPro; IPR035899; DBL_dom_sf.
DR InterPro; IPR000219; DH-domain.
DR InterPro; IPR011993; PH-like_dom_sf.
DR InterPro; IPR001849; PH_domain.
DR PANTHER; PTHR47056; RHO GUANINE NUCLEOTIDE EXCHANGE FACTOR 39; 1.
DR PANTHER; PTHR47056:SF1; RHO GUANINE NUCLEOTIDE EXCHANGE FACTOR 39; 1.
DR Pfam; PF00621; RhoGEF; 1.
DR SMART; SM00233; PH; 1.
DR SMART; SM00325; RhoGEF; 1.
DR SUPFAM; SSF48065; DBL homology domain (DH-domain); 1.
DR SUPFAM; SSF50729; PH domain-like; 1.
DR PROSITE; PS50010; DH_2; 1.
DR PROSITE; PS50003; PH_DOMAIN; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000079721}.
FT DOMAIN 22..197
FT /note="DH"
FT /evidence="ECO:0000259|PROSITE:PS50010"
FT DOMAIN 227..331
FT /note="PH"
FT /evidence="ECO:0000259|PROSITE:PS50003"
SQ SEQUENCE 335 AA; 38428 MW; D0163DFFDBD0A273 CRC64;
MGSPSRSARC PVLEQRARWE RKRACTAREL LETERRYQEQ LGLVATYFVG ILKAKGTLRP
PERQALFGPW ELIYGASQEL LPYLERGHWG LGLEGFCTHL EFYTQFAANA EKSRTTLQEQ
LKKSKRFRRF VQLQEGRPEF GGLQLQDLLP LPLQRLQQYE NLVVALAENT NPNSPDHQQL
TRAARLISET AQRVHVIGQK QKNDRHLQRI QALLSGRQAK GLTTGRWFLR QGWLLVVPPH
GEPRPRMFFL FSDMLLVAKP RPPLHLLQSG TFVCRALYPM AQCQLERIFG HSGGPCGGLL
SLSFPHEKLL LMSTDQEELS RWYHSLTLAI SSQKN
//
