ID A0A1S2ZQF1_ERIEU Unreviewed; 86 AA.
AC A0A1S2ZQF1;
DT 12-APR-2017, integrated into UniProtKB/TrEMBL.
DT 12-APR-2017, sequence version 1.
DT 27-MAR-2024, entry version 26.
DE SubName: Full=Serine protease inhibitor Kazal-type 4 {ECO:0000313|RefSeq:XP_007522929.1};
GN Name=SPINK4 {ECO:0000313|RefSeq:XP_007522929.1};
OS Erinaceus europaeus (Western European hedgehog).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Laurasiatheria; Eulipotyphla; Erinaceidae; Erinaceinae;
OC Erinaceus.
OX NCBI_TaxID=9365 {ECO:0000313|Proteomes:UP000079721, ECO:0000313|RefSeq:XP_007522929.1};
RN [1] {ECO:0000313|RefSeq:XP_007522929.1}
RP IDENTIFICATION.
RG RefSeq;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Secreted {ECO:0000256|ARBA:ARBA00004613}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR RefSeq; XP_007522929.1; XM_007522867.2.
DR AlphaFoldDB; A0A1S2ZQF1; -.
DR STRING; 9365.ENSEEUP00000011876; -.
DR GeneID; 103113340; -.
DR CTD; 27290; -.
DR eggNOG; KOG3649; Eukaryota.
DR InParanoid; A0A1S2ZQF1; -.
DR OrthoDB; 2920086at2759; -.
DR Proteomes; UP000079721; Unplaced.
DR GO; GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell.
DR GO; GO:0004867; F:serine-type endopeptidase inhibitor activity; IEA:InterPro.
DR Gene3D; 3.30.60.30; -; 1.
DR InterPro; IPR002350; Kazal_dom.
DR InterPro; IPR036058; Kazal_dom_sf.
DR InterPro; IPR039932; Spink4-like.
DR PANTHER; PTHR21179:SF0; SERINE PROTEASE INHIBITOR KAZAL-TYPE 4; 1.
DR PANTHER; PTHR21179; SERINE-TYPE ENDOPEPTIDASE INHIBITOR; 1.
DR Pfam; PF00050; Kazal_1; 1.
DR SMART; SM00280; KAZAL; 1.
DR SUPFAM; SSF100895; Kazal-type serine protease inhibitors; 1.
DR PROSITE; PS00282; KAZAL_1; 1.
DR PROSITE; PS51465; KAZAL_2; 1.
PE 4: Predicted;
KW Disulfide bond {ECO:0000256|ARBA:ARBA00023157};
KW Protease inhibitor {ECO:0000313|RefSeq:XP_007522929.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000079721};
KW Secreted {ECO:0000256|ARBA:ARBA00022525}; Signal {ECO:0000256|SAM:SignalP}.
FT SIGNAL 1..20
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 21..86
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5010356516"
FT DOMAIN 31..86
FT /note="Kazal-like"
FT /evidence="ECO:0000259|PROSITE:PS51465"
SQ SEQUENCE 86 AA; 9367 MW; 72EA16C60883A675 CRC64;
MAGHLCVVAL AFITLLTVDR EVPVSAGKPI FSRMPICEHM AENPDCSKMS SPVCGTDGVT
YDSECQLCLT RMETKQDIQV TKDAKC
//
