ID A0A1S2ZS16_ERIEU Unreviewed; 318 AA.
AC A0A1S2ZS16;
DT 12-APR-2017, integrated into UniProtKB/TrEMBL.
DT 12-APR-2017, sequence version 1.
DT 27-MAR-2024, entry version 28.
DE SubName: Full=Forkhead box protein R1 {ECO:0000313|RefSeq:XP_007523661.1};
GN Name=FOXR1 {ECO:0000313|RefSeq:XP_007523661.1};
OS Erinaceus europaeus (Western European hedgehog).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Laurasiatheria; Eulipotyphla; Erinaceidae; Erinaceinae;
OC Erinaceus.
OX NCBI_TaxID=9365 {ECO:0000313|Proteomes:UP000079721, ECO:0000313|RefSeq:XP_007523661.1};
RN [1] {ECO:0000313|RefSeq:XP_007523661.1}
RP IDENTIFICATION.
RG RefSeq;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|PROSITE-ProRule:PRU00089}.
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DR RefSeq; XP_007523661.1; XM_007523599.1.
DR AlphaFoldDB; A0A1S2ZS16; -.
DR STRING; 9365.ENSEEUP00000009636; -.
DR GeneID; 103113982; -.
DR CTD; 283150; -.
DR eggNOG; KOG2294; Eukaryota.
DR InParanoid; A0A1S2ZS16; -.
DR OrthoDB; 5385885at2759; -.
DR Proteomes; UP000079721; Unplaced.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0003700; F:DNA-binding transcription factor activity; IEA:InterPro.
DR GO; GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.
DR CDD; cd20036; FH_FOXR; 1.
DR Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 1.
DR InterPro; IPR001766; Fork_head_dom.
DR InterPro; IPR036388; WH-like_DNA-bd_sf.
DR InterPro; IPR036390; WH_DNA-bd_sf.
DR PANTHER; PTHR46789; FORKHEAD BOX PROTEIN R1; 1.
DR PANTHER; PTHR46789:SF1; FORKHEAD BOX PROTEIN R1; 1.
DR Pfam; PF00250; Forkhead; 1.
DR PRINTS; PR00053; FORKHEAD.
DR SMART; SM00339; FH; 1.
DR SUPFAM; SSF46785; Winged helix' DNA-binding domain; 1.
DR PROSITE; PS50039; FORK_HEAD_3; 1.
PE 4: Predicted;
KW DNA-binding {ECO:0000256|ARBA:ARBA00023125, ECO:0000256|PROSITE-
KW ProRule:PRU00089}; Nucleus {ECO:0000256|PROSITE-ProRule:PRU00089};
KW Reference proteome {ECO:0000313|Proteomes:UP000079721}.
FT DOMAIN 199..298
FT /note="Fork-head"
FT /evidence="ECO:0000259|PROSITE:PS50039"
FT DNA_BIND 199..298
FT /note="Fork-head"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00089"
FT REGION 129..149
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 155..174
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 318 AA; 36311 MW; 9C98D950DEDC9E95 CRC64;
MELQLRDTDF WASLHGTVPG LLDWDMGNEC FLPFTTSHLS TAEQNLALYR LRIVKPPGLP
LEKKPNPDKD GPDIEPNLWM WVNPNIVYPP GKLEVSKPIK EEDLMNLLPS PQLPPKEEDS
DNCSEITVAE SLPPSSSEQS PPQKWFASSP SCCELTEEEE AEDQDDSSSV ACLSPHKRAP
LQSRRLRHTS SQEGRLWSRP PLNYFHLIAL ALRNSSPCGL NVQQIYGFTR QHFPFFRTAP
EGWKNTIRHN LCFRDSFEKV PVSMQVGGSI RPQSCLWKLT EKGHRRFLEE TRTLASTRLE
CLRQCMSQPD MMPLLFDL
//
