ID A0A1S2ZT80_ERIEU Unreviewed; 789 AA.
AC A0A1S2ZT80;
DT 12-APR-2017, integrated into UniProtKB/TrEMBL.
DT 12-APR-2017, sequence version 1.
DT 27-MAR-2024, entry version 27.
DE SubName: Full=Nuclear cap-binding protein subunit 1 {ECO:0000313|RefSeq:XP_007524183.1};
GN Name=NCBP1 {ECO:0000313|RefSeq:XP_007524183.1};
OS Erinaceus europaeus (Western European hedgehog).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Laurasiatheria; Eulipotyphla; Erinaceidae; Erinaceinae;
OC Erinaceus.
OX NCBI_TaxID=9365 {ECO:0000313|Proteomes:UP000079721, ECO:0000313|RefSeq:XP_007524183.1};
RN [1] {ECO:0000313|RefSeq:XP_007524183.1}
RP IDENTIFICATION.
RG RefSeq;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
CC -!- SIMILARITY: Belongs to the NCBP1 family.
CC {ECO:0000256|ARBA:ARBA00007413}.
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DR RefSeq; XP_007524183.1; XM_007524121.2.
DR AlphaFoldDB; A0A1S2ZT80; -.
DR STRING; 9365.ENSEEUP00000014588; -.
DR GeneID; 103114430; -.
DR CTD; 4686; -.
DR eggNOG; KOG1104; Eukaryota.
DR InParanoid; A0A1S2ZT80; -.
DR OrthoDB; 5477544at2759; -.
DR Proteomes; UP000079721; Unplaced.
DR GO; GO:0005846; C:nuclear cap binding complex; IEA:InterPro.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0000339; F:RNA cap binding; IEA:InterPro.
DR GO; GO:0006370; P:7-methylguanosine mRNA capping; IEA:UniProtKB-KW.
DR GO; GO:0006406; P:mRNA export from nucleus; IEA:InterPro.
DR GO; GO:0000184; P:nuclear-transcribed mRNA catabolic process, nonsense-mediated decay; IEA:UniProtKB-KW.
DR GO; GO:0008380; P:RNA splicing; IEA:UniProtKB-KW.
DR Gene3D; 1.25.40.180; -; 3.
DR InterPro; IPR016024; ARM-type_fold.
DR InterPro; IPR027159; CBP80.
DR InterPro; IPR015172; MIF4G-like_typ-1.
DR InterPro; IPR015174; MIF4G-like_typ-2.
DR InterPro; IPR003890; MIF4G-like_typ-3.
DR PANTHER; PTHR12412; CAP BINDING PROTEIN; 1.
DR PANTHER; PTHR12412:SF2; NUCLEAR CAP-BINDING PROTEIN SUBUNIT 1; 1.
DR Pfam; PF02854; MIF4G; 1.
DR Pfam; PF09088; MIF4G_like; 1.
DR Pfam; PF09090; MIF4G_like_2; 1.
DR SMART; SM00543; MIF4G; 1.
DR SUPFAM; SSF48371; ARM repeat; 3.
PE 3: Inferred from homology;
KW mRNA capping {ECO:0000256|ARBA:ARBA00023042};
KW mRNA processing {ECO:0000256|ARBA:ARBA00022664};
KW mRNA splicing {ECO:0000256|ARBA:ARBA00023187};
KW mRNA transport {ECO:0000256|ARBA:ARBA00022816};
KW Nonsense-mediated mRNA decay {ECO:0000256|ARBA:ARBA00023161};
KW Nucleus {ECO:0000256|ARBA:ARBA00023242};
KW Reference proteome {ECO:0000313|Proteomes:UP000079721};
KW Transport {ECO:0000256|ARBA:ARBA00022816}.
FT DOMAIN 28..240
FT /note="MIF4G"
FT /evidence="ECO:0000259|SMART:SM00543"
FT REGION 1..26
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 666..685
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 789 AA; 91729 MW; A9C9E017BB05677B CRC64;
MSRRRHSDEN DGGQPHKRRK TSDANETEDH LESLICKVGE KSACSLESNL EGLAGVLEAD
LPNYKSKILR LLCTVARLLP EKLTIYTTLV GLLNARNYNF GGEFVEAMIR QLKESLKSNN
YNEAVYLVRF LSDLVNCHVI AAPSMVAMFE NFVSVTQEED VPQVRRDWYV YAFLSSLPWV
GKELYEKKDA EMDRIFTNTE SYLKRRLKTH VPMLQVWTAE KPHPQEEYLD CLWAQIQKLK
KDHWQERHIL RPYLAFDSVL CEALQHNLPP FTPPPHTEDS VYPVPRVIFR MFDYTDDPEG
PVMPGSHSVE RFVIEENLHC IIKSHWKERK TCAAQLVSYP GKNKIPLNYH IVEVIFAELF
QLPAPPHIDV MYTTLLIELC KLQPGSLPQV LAQATEMLYM RLDTMNTTCV DRFINWFSHH
LNNFQFRWSW EDWSDCLTQD PESPKPKFVR EVLEKCMRLS YHQRILDIVP PTFSALCPAN
PTCIYKYGDE SSNALPGHSA ALCLSVAFKS KATNDEIFSI LKDVPNPNQE DDDDEGFSFN
PLKIEVFVQT LLHLAAKSFS HSFSALAKFH EVFKTLAESD EGKLHVLRVM FEVWRNHPQM
IAVLVDKMIR TQIVDCAAVA NWIFSSELSR DFIRLFVWEI LHSTIRKMNK HVLKIQKELE
EAKEKLARQH KRRSDDDRSS DRKDGALEEQ IERLQEKVES AQSEQKNLFL VIFQRFIMIL
TEHLVRCETD GTSILTPWYK NCIERLQQIF LQHHQIIQQY MVTLENLLFT AELDPHILAV
FQQFCALQA
//
