ID   A0A1S2ZTP6_ERIEU        Unreviewed;       235 AA.
AC   A0A1S2ZTP6;
DT   12-APR-2017, integrated into UniProtKB/TrEMBL.
DT   12-APR-2017, sequence version 1.
DT   27-MAR-2024, entry version 26.
DE   SubName: Full=Transmembrane emp24 domain-containing protein 9 isoform X1 {ECO:0000313|RefSeq:XP_007524391.1};
GN   Name=TMED9 {ECO:0000313|RefSeq:XP_007524391.1};
OS   Erinaceus europaeus (Western European hedgehog).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Laurasiatheria; Eulipotyphla; Erinaceidae; Erinaceinae;
OC   Erinaceus.
OX   NCBI_TaxID=9365 {ECO:0000313|Proteomes:UP000079721, ECO:0000313|RefSeq:XP_007524391.1};
RN   [1] {ECO:0000313|RefSeq:XP_007524391.1}
RP   IDENTIFICATION.
RG   RefSeq;
RL   Submitted (NOV-2023) to UniProtKB.
CC   -!- SUBCELLULAR LOCATION: Endoplasmic reticulum membrane
CC       {ECO:0000256|ARBA:ARBA00004115}; Single-pass type I membrane protein
CC       {ECO:0000256|ARBA:ARBA00004115}. Membrane
CC       {ECO:0000256|ARBA:ARBA00004479, ECO:0000256|RuleBase:RU003827}; Single-
CC       pass type I membrane protein {ECO:0000256|ARBA:ARBA00004479,
CC       ECO:0000256|RuleBase:RU003827}.
CC   -!- SIMILARITY: Belongs to the EMP24/GP25L family.
CC       {ECO:0000256|ARBA:ARBA00007104, ECO:0000256|RuleBase:RU003827}.
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DR   RefSeq; XP_007524391.1; XM_007524329.2.
DR   AlphaFoldDB; A0A1S2ZTP6; -.
DR   STRING; 9365.ENSEEUP00000011734; -.
DR   GeneID; 103114629; -.
DR   eggNOG; KOG1690; Eukaryota.
DR   InParanoid; A0A1S2ZTP6; -.
DR   OrthoDB; 886406at2759; -.
DR   Proteomes; UP000079721; Unplaced.
DR   GO; GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.
DR   InterPro; IPR015720; Emp24-like.
DR   InterPro; IPR009038; GOLD_dom.
DR   PANTHER; PTHR22811; TRANSMEMBRANE EMP24 DOMAIN-CONTAINING PROTEIN; 1.
DR   PANTHER; PTHR22811:SF37; TRANSMEMBRANE EMP24 DOMAIN-CONTAINING PROTEIN 9; 1.
DR   Pfam; PF01105; EMP24_GP25L; 1.
DR   SMART; SM01190; EMP24_GP25L; 1.
DR   PROSITE; PS50866; GOLD; 1.
PE   3: Inferred from homology;
KW   Coiled coil {ECO:0000256|SAM:Coils};
KW   Endoplasmic reticulum {ECO:0000256|ARBA:ARBA00022824};
KW   Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW   Reference proteome {ECO:0000313|Proteomes:UP000079721};
KW   Signal {ECO:0000256|ARBA:ARBA00022729, ECO:0000256|SAM:SignalP};
KW   Transmembrane {ECO:0000256|ARBA:ARBA00022692,
KW   ECO:0000256|RuleBase:RU003827};
KW   Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW   ECO:0000256|SAM:Phobius}.
FT   SIGNAL          1..37
FT                   /evidence="ECO:0000256|SAM:SignalP"
FT   CHAIN           38..235
FT                   /evidence="ECO:0000256|SAM:SignalP"
FT                   /id="PRO_5010335331"
FT   TRANSMEM        203..222
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   DOMAIN          47..145
FT                   /note="GOLD"
FT                   /evidence="ECO:0000259|PROSITE:PS50866"
FT   COILED          154..181
FT                   /evidence="ECO:0000256|SAM:Coils"
SQ   SEQUENCE   235 AA;  27045 MW;  DD45712490C669FA CRC64;
     MAAERGVRVS GARPAAGLGR LVRAYLLLLC CAARGGALYF HIGETEKKCF IEEIPDETMV
     IGNYRTQLYD KQREEYQPAT PGLGMFVEVK DPEDKLILAR QYGSEGRFTF TSHTPGEHQI
     CLHSNSTKFS LFAGGMLRVH LDIQVGEHAN DYAEIAAKDK LSELQLRVRQ LVEQVEQIQK
     EQNYQRWREE RFRQTSESTN QRVLWWSILQ TLILVAIGVW QMRHLKSFFE AKKLV
//