ID A0A1S2ZW51_ERIEU Unreviewed; 1873 AA.
AC A0A1S2ZW51;
DT 12-APR-2017, integrated into UniProtKB/TrEMBL.
DT 12-APR-2017, sequence version 1.
DT 27-MAR-2024, entry version 31.
DE SubName: Full=Girdin {ECO:0000313|RefSeq:XP_007525526.1};
GN Name=CCDC88A {ECO:0000313|RefSeq:XP_007525526.1};
OS Erinaceus europaeus (Western European hedgehog).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Laurasiatheria; Eulipotyphla; Erinaceidae; Erinaceinae;
OC Erinaceus.
OX NCBI_TaxID=9365 {ECO:0000313|Proteomes:UP000079721, ECO:0000313|RefSeq:XP_007525526.1};
RN [1] {ECO:0000313|RefSeq:XP_007525526.1}
RP IDENTIFICATION.
RG RefSeq;
RL Submitted (NOV-2023) to UniProtKB.
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DR RefSeq; XP_007525526.1; XM_007525464.2.
DR STRING; 9365.ENSEEUP00000010080; -.
DR GeneID; 103115671; -.
DR CTD; 55704; -.
DR eggNOG; KOG4643; Eukaryota.
DR InParanoid; A0A1S2ZW51; -.
DR OrthoDB; 3091995at2759; -.
DR Proteomes; UP000079721; Unplaced.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.
DR GO; GO:0030705; P:cytoskeleton-dependent intracellular transport; IEA:InterPro.
DR CDD; cd22229; HkD_Girdin; 1.
DR Gene3D; 1.10.418.10; Calponin-like domain; 1.
DR InterPro; IPR001715; CH_dom.
DR InterPro; IPR036872; CH_dom_sf.
DR InterPro; IPR043936; HOOK_N.
DR PANTHER; PTHR18947:SF30; GIRDIN; 1.
DR PANTHER; PTHR18947; HOOK PROTEINS; 1.
DR Pfam; PF19047; HOOK_N; 1.
DR SUPFAM; SSF116907; Hook domain; 1.
DR PROSITE; PS50021; CH; 1.
PE 4: Predicted;
KW Coiled coil {ECO:0000256|ARBA:ARBA00023054, ECO:0000256|SAM:Coils};
KW Cytoplasm {ECO:0000256|ARBA:ARBA00022490};
KW Reference proteome {ECO:0000313|Proteomes:UP000079721}.
FT DOMAIN 12..132
FT /note="Calponin-homology (CH)"
FT /evidence="ECO:0000259|PROSITE:PS50021"
FT REGION 223..242
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1007..1036
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1406..1460
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1559..1601
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1728..1873
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 190..217
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 246..425
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 1124..1231
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 1274..1382
FT /evidence="ECO:0000256|SAM:Coils"
FT COMPBIAS 226..242
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1415..1460
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1744..1760
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1763..1778
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1792..1821
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1857..1873
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1873 AA; 216209 MW; 58CE47ED667BFF2E CRC64;
MENEIFTPLL EQFMTSPLVT WVKTFGPLAA GNGTNLDEYV ALVDGVFLNQ VMHQINPKSE
SQRVNKKVNN DASLRIHNLS ILVKQIKFYY QETLQQLIMM SLPNVLTLGK NPFSEQGTEE
VKKLLLLLLG CAVQCQKKEE FIERIQGLDF DTKAAVAAHI QEVTHNQENV FDLQWMEVTD
MSQEEVEPLL KNMASHLKRL IDERDEHSET IVELSEERDG LHFLPHPSSS AQSPCGSPGM
KRTESRQHLS VELADAKAKI RRLRQELEEK TEQLLDCKQE LEQMEIELKR LQQENMNLLS
DARSARMYRD ELDALREKAI RVDKLESEVS RYKERLHDIE FYKARVEELK EDNQVLLETK
TMLEDQLEGT RARSDKLHEL EKENLQLKAK LHDMEMERDM DRKKIEELME ENMTLEMAQK
QSMDESLHLG WELEQISKTS EISEAPQKSL GHEVNELTSS RLLKLEMENQ SLTKTVEELR
SAMDSAEGST SKILKMEKEN QRLSKKVEIL ENEIIQEKQS LQNCQDLSKD LMKEKAQLEK
TIETLRENSE RQIKILEQEN EHLNQTVSSL RQRSQIGAEA RVKDIEKENK ILHESIKETS
SKLSKTEFEK RQIKKELEHF KEKGERAEEL ENELHRLEKE NELLQKKITN LKITCEKIEA
LELENSELER ENRKLKKTLD SLKNLTFQLE SLEKENSQLD EENLELRRNV ESLKCASMKM
AQLQLENKEL ESEKEQLKKG LELMKASFKK TERLEVSYQG LDTENQRLQK ALENSNKKIQ
QLESELQDLE MENQTLQKNL EELKISSKRL EQLEKENKSL EQETSQLEKD KKQLEKENKR
LRQQAEIKDT TLEENNVKIG NLEKENKTLF KEVGIYKESS LRLKELEKEN KELVKKATID
IKTLVTLRED LVSEKLKTQQ MNNDLEKLTH ELEKIGLNKE RLLHDEQSTD DRYKLLESKL
ESTLKKSLEI KEEKIAALEA RLEESTNYNQ QLRQELKTVK KNYEALKQRQ DEERMVQSSP
PTSGEDNKWE RESQETTREL LKVKDRLIEV ERNNATLQAE KQALKTQLKQ LETQNNNLQA
QILALQRQTV SLQEQNTTLQ TQNAKLQVEN STLNSQSTSL MNQNAQLLIQ QSSLENENES
VIKEREDLKS LYDSLIKDHE KLELLHERQA SEYESLIAKH GTLKSAHKNL EVEHKDLEDR
YNQLLKQKGQ LEDLEKTLKV EQEKMQLQNK SHETIAAEYK KLCGENDRLN HTYNQLLKDT
DVLQTDHKNL KSLLNSSKLE QTRLEAEFSK LKEQYQQLDI TSTKLNNQCE LLSQLKGNLE
EENRHLLDQI QTLMLQNRTL LEQNMESKDL FHVEQRQYID KLNELRRQKE KLEEKIMDQY
KFYDPSPPRR RGNWITLKMR KLIKSKKDIN RERQKSLTLT PTRSDSSEGF LQLPHQDSQD
SSSVGSNSLE DGQTMGTKKS SMVALKRLPF LRNRPKDKDK MKACYRRSMS MNDLVQSMVL
AGGQWTGSTE NLEVPDDIST GKRRKELGAM AFSTTAINFS TVNSSTGIRS KQLVNNKDTT
SFEDISPQGI SDDSSTGSRV HASRPASLDS GRTSTSNSNN NATLHEVKAG AVHIQSRPQS
HSSGEFSLLH DHEAWSSSGS SPIQYLKRQT RSSPVLQQKM PETLESRAYH RIKTGSPGSE
VVTLQQFLEE SNKLTSIQIK SSSQENLLDE VMKSLSVSSD FLGKHKPVSC GLARSVSGKT
PGDFYDRRTT KPEQFVKLGP RKTEDTYSNS SPGKPTPSTQ GKRKLVKEIS LSRQSKDNNP
YATLPRASSV ISTAEGTTRR TSIHDLLTKD SKLPISVDSP PATIDSIITA APNMDKVQES
RKSKSRSREQ QSS
//
