ID A0A1S2ZX19_ERIEU Unreviewed; 3112 AA.
AC A0A1S2ZX19;
DT 12-APR-2017, integrated into UniProtKB/TrEMBL.
DT 12-APR-2017, sequence version 1.
DT 27-MAR-2024, entry version 26.
DE SubName: Full=Centrosome-associated protein 350 {ECO:0000313|RefSeq:XP_007525911.1};
GN Name=CEP350 {ECO:0000313|RefSeq:XP_007525911.1};
OS Erinaceus europaeus (Western European hedgehog).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Laurasiatheria; Eulipotyphla; Erinaceidae; Erinaceinae;
OC Erinaceus.
OX NCBI_TaxID=9365 {ECO:0000313|Proteomes:UP000079721, ECO:0000313|RefSeq:XP_007525911.1};
RN [1] {ECO:0000313|RefSeq:XP_007525911.1}
RP IDENTIFICATION.
RG RefSeq;
RL Submitted (NOV-2023) to UniProtKB.
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DR RefSeq; XP_007525911.1; XM_007525849.2.
DR STRING; 9365.ENSEEUP00000001000; -.
DR CTD; 9857; -.
DR eggNOG; KOG4568; Eukaryota.
DR InParanoid; A0A1S2ZX19; -.
DR OrthoDB; 2914816at2759; -.
DR Proteomes; UP000079721; Unplaced.
DR GO; GO:0005813; C:centrosome; IEA:InterPro.
DR GO; GO:0008017; F:microtubule binding; IEA:InterPro.
DR GO; GO:0034453; P:microtubule anchoring; IEA:InterPro.
DR Gene3D; 2.30.30.190; CAP Gly-rich-like domain; 1.
DR InterPro; IPR036859; CAP-Gly_dom_sf.
DR InterPro; IPR000938; CAP-Gly_domain.
DR InterPro; IPR028750; CEP350/CC187.
DR InterPro; IPR025486; DUF4378.
DR PANTHER; PTHR13958; CENTROSOME-ASSOCIATED PROTEIN 350; 1.
DR PANTHER; PTHR13958:SF4; CENTROSOME-ASSOCIATED PROTEIN 350; 1.
DR Pfam; PF01302; CAP_GLY; 1.
DR Pfam; PF14309; DUF4378; 1.
DR SMART; SM01052; CAP_GLY; 1.
DR SUPFAM; SSF74924; Cap-Gly domain; 1.
DR PROSITE; PS00845; CAP_GLY_1; 1.
DR PROSITE; PS50245; CAP_GLY_2; 1.
PE 4: Predicted;
KW Coiled coil {ECO:0000256|SAM:Coils};
KW Reference proteome {ECO:0000313|Proteomes:UP000079721}.
FT DOMAIN 2514..2556
FT /note="CAP-Gly"
FT /evidence="ECO:0000259|PROSITE:PS50245"
FT REGION 1..29
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 434..520
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 541..625
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 673..720
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 859..878
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 956..999
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1109..1131
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1149..1176
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1196..1265
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1492..1673
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1725..1744
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1792..1859
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1898..2083
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 2110..2160
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 2326..2352
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 2400..2431
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 815..849
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 1380..1409
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 1866..1893
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 2715..2742
FT /evidence="ECO:0000256|SAM:Coils"
FT COMPBIAS 439..460
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 473..498
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 566..625
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 702..716
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 956..985
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1109..1124
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1149..1168
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1207..1222
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1229..1265
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1492..1518
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1553..1568
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1570..1584
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1591..1606
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1608..1655
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1657..1673
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1792..1814
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1815..1842
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1843..1859
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1903..1925
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1977..2045
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 2046..2083
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 2110..2126
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 2132..2160
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 3112 AA; 350535 MW; 7B4A64D771D130AA CRC64;
MKSSKSKEVP LSNPRNSQSK ETVQADVSTS WDALSQTKAA LRHIENKLEV APTSTAVFDS
VMDTKKSSAS AIRKISRKDG RYLDDSWVNA PTSKTSKLRK EKSRSPLRAT TLESNVKKNT
RVEFREPLVS YREIHGTHSI LSPSHVESKH VYHMDVDEEK TQGGNQLTSN QERNLHCCDF
ESSQSSLISD TVVRFLNDGP AIDALQNSEC LIKMPAPVRT EEEKPNKAKG NENRLKTSVS
NMGQYVDPKV LRLADSSPSS TSTSNSQRLD ILKRRQHDVK LEKLKERIRK QWEHSEETNG
RGQSVGHSDY PVMVVNIDNS VTAKVRKVAT APPAPMYKGF NPSETKIRTP DGKVWQEAEF
QTMSRELYRD LAFHFSDDIS MKEKPAEKIK EKKVAKPVRK VQKVAQLTGS ECKTGSSRLI
STSSWRDGQK LVKKILGPAP RMEQKERRAA SSERSGRERT TKSGGPIGRA ESDPRLDASH
KYLSRNSECS RSRARSENNI KKLVPSLPDN KQEENTALKK DFLPDEIRGI LDDLQLDSAA
QDTRQEVEEL QNQKASPPVQ VSRSHSPVKR KPDRITANED PPVISKKRHY DTDEVRQYIV
RQQEERKRKQ NEEKKAQKEA TEQKNKRLQE LYRKQKEAFT KAKNVPPEPP ASRRLQETYS
KLLLEKTLLE EPAHQHVVQE TQIKPGYQPS GESDKENKVQ ERPPSASSSS DLSLSEPPQP
LARRDLMEPT WMQPDRLSPR VHHSQPQSLG TAGNLLSHLL SVDRVGILHK DFESILPTKK
NRNMASGPLT FTPQPYLTSP AAHPDALLKP SVSQYKSKLD RIEALKATAA SLSNRIENEA
KKLAGANINY GSVWNSEYDV QQRPQEDEPW AKSVSPPVKE DTEDIFSARI QKMLGTCVSH
ATFDDDLPGV GNLSEFKKLP EMIRPHSAIS SLRITSPGPK PEGLLAQLCK RTIDSSSSDV
QASSPGKAKR SLGSSNDSVS EGPLLSEGSL SEEEGGQDQR PLLKVAEILK EKEFCAGERN
TYEPIKEFQK EAEKFLPIFG HIGGTQSKGP WEELAKGSPH SVINIFTKSY QLYGKGFDDK
LERGTSASRP LNAITTPLSS ISYEDDFVSS PGSGTLTEKK STLEPNSLGI EEDHSCRKSA
YELSSVDATC QHSSGGQSPA SSCSSTASKG KKGKKEQMEW LDSLTGSIQN TILDEEKVHS
GSERGSHQGK KSGTSSRLSV KDYEQTFDTD STLEDVSGHS LSVSLDKGRS QKTPTSPLSP
SSQKLLQFDL PGSSLERSKS SVTVSPTTTG FKSNAAFTDL PVSRTASEKA STPGTKRFSP
AGLQHRMTAE LSYLSAIEES VRQLSDVERV RGISLAQQES VSLAQIIKAQ QQRHERDLAL
LKLKAEQEAL ECQRQLEETR NKAAQAHAES LQQVVKSQRE VTDVLQETTY KIAAQQTETA
RLTTDAARQI CEMAELTRTH ISGAITASGA PLATLYDHHR QQTSDFVKQL RTRAETDRKS
HSVSLSQSKE ETIDSKHQKY SPSYDSYSES SRCKNHDRRS SSGSSHQESP SGPSSKENKK
KLHGEKMGSS IEEQVQTAAD DSLGSDSVPS LPDEKDSTSI ATEYSLKFDE SMTEDEIEEK
SFRSLLPSES HRRFNMEKKR GHHDDSDEEP SPEKTALSSA KELSMPFSGG QDSFSKFTME
MVRQYMKEEE MRAAHQSSLL RLREKALKEK TKAELAWLEH QKKHLRDKGE DDKMPPLRKK
QRGLLLRLQQ EKAEIKRLQE ANKAARKERQ LILKQQEEIE RIRQTTIKLQ EKLKSAGENK
LDSHSDDDSK DNKATSPGPT DLETRSPSPI SISSSETSSI MQKLKKMRSR MDEKFLTKRE
QKLMQRRQHA EELLEWKRRL DAEEAEIRQM EKQALAAWDT ELMKPKTPKK ELENSRSENK
EIVSEEESPL PSYSHLHSES SIPEDLGSAA VEYMPSESRV QEQHGSPDHS ILTEEMVFSQ
ELESSTSPNK HSPLKSCTSV SKQESSKTSH ENGGQYRLSV KSHQHCSSWS DESLSMTQSE
TTSDQSDIEG RIRALKDELR KRKSVVDQLK KEQKKRQKER LKAQEASLIK QLESYDEFIK
KTEAELNQDL EISPTAKPQI KTLSSASEKP KIKPLPLHRS ETAKNWKSLT ESERSRGSLE
SIAEHVDATL SSSDRSVSEK SLSSFAKGAI ELDNQTGEHF QTSSPILQSL RKIRAESGDC
LENVPSLPLL KELNAPNKIL DISDVKAEEE FAQKSEIQEA KCIKLEESAI EGAYSKPSRK
PDVLVKLDLE QGDSTEIPSK KDLPLDSTSV QRDLVKLAIK NLHEELRERQ SNQDMDHSPD
IQPEKNIHEQ KNIKERDLFL SSHLSAPKER TYAEDFEVSS FKKESSAELY NDDFEVSSLS
SSRKDSQSCR DKSQPTRNSR SRATSFGSDD EISECLSEKS LSVHSNVHSE RLLELKSPTE
LMKSKERSDV GHEQGITEFP SLASVSMADE LLDFHIGDRV LIGNVQPGTL RFKGLTSFAE
GFWAGVELDK PEGNNNGTYD GIIYFVCKEK HGIFAPPQKI SHIPENFDDY VDINEDEDCY
PDEQYQYCNQ EQKDKEGLNL DREKDATEYS YEKSLPSMHN IEVSVDRSLK IETESIQDIS
GAFETYVHQK SSVDSLISKE NKDLVSNAME KVSTAVEDDT LDNTFPEDLK KQQQLANKQE
DLYSEVPETF STPLLDLLRR EKNQLEAQLK SSLKEGKKSK EQLETVTSLT DSLLNVFVKD
TVNQLQQIKK SRNEKIHLSN QELLDDNQKE MLPADLFHNL EEQSPGVPDC YLRSELEDEK
EEMSSPDMCP RPESPVFGAS GQEELAKRLA ELEISREFLS VLGDDQDWFD EDFGLSSSPK
IPKSKAEESI VPLMAEPKRA SKKPCETLLA VPHTAEEVEI LVHNAAEELW KWKELGHDLH
SISIPATLLG FASKGLDIES ISKRVYKQAV FDLTKEIFEE IFAEDPNLNQ PIWMKPCRIN
SSYFRRVKNP NSLEEIKNFI ATEVLKLFSL KKEPNHKMDW QKMMKFGRKK RDRVDHILVQ
ELHEEEAQWV NYDEDELCVK MQLADGIFET LIRDTIDVLN QISEKQGRML LV
//
