ID   A0A1S2ZZE3_ERIEU        Unreviewed;       468 AA.
AC   A0A1S2ZZE3;
DT   12-APR-2017, integrated into UniProtKB/TrEMBL.
DT   12-APR-2017, sequence version 1.
DT   27-MAR-2024, entry version 25.
DE   SubName: Full=DENN domain-containing protein 2D isoform X1 {ECO:0000313|RefSeq:XP_007526987.1};
GN   Name=DENND2D {ECO:0000313|RefSeq:XP_007526987.1};
OS   Erinaceus europaeus (Western European hedgehog).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Laurasiatheria; Eulipotyphla; Erinaceidae; Erinaceinae;
OC   Erinaceus.
OX   NCBI_TaxID=9365 {ECO:0000313|Proteomes:UP000079721, ECO:0000313|RefSeq:XP_007526987.1};
RN   [1] {ECO:0000313|RefSeq:XP_007526987.1}
RP   IDENTIFICATION.
RG   RefSeq;
RL   Submitted (NOV-2023) to UniProtKB.
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DR   RefSeq; XP_007526987.1; XM_007526925.2.
DR   AlphaFoldDB; A0A1S2ZZE3; -.
DR   GeneID; 103116963; -.
DR   CTD; 79961; -.
DR   OrthoDB; 5398783at2759; -.
DR   Proteomes; UP000079721; Unplaced.
DR   GO; GO:0005085; F:guanyl-nucleotide exchange factor activity; IEA:UniProtKB-KW.
DR   Gene3D; 3.30.450.200; -; 1.
DR   Gene3D; 3.40.50.11500; -; 1.
DR   InterPro; IPR001194; cDENN_dom.
DR   InterPro; IPR005112; dDENN_dom.
DR   InterPro; IPR043153; DENN_C.
DR   InterPro; IPR037516; Tripartite_DENN.
DR   InterPro; IPR005113; uDENN_dom.
DR   PANTHER; PTHR15288; DENN DOMAIN-CONTAINING PROTEIN 2; 1.
DR   PANTHER; PTHR15288:SF2; DENN DOMAIN-CONTAINING PROTEIN 2D; 1.
DR   Pfam; PF03455; dDENN; 1.
DR   Pfam; PF02141; DENN; 1.
DR   Pfam; PF03456; uDENN; 1.
DR   SMART; SM00801; dDENN; 1.
DR   SMART; SM00799; DENN; 1.
DR   SMART; SM00800; uDENN; 1.
DR   PROSITE; PS50211; DENN; 1.
PE   4: Predicted;
KW   Guanine-nucleotide releasing factor {ECO:0000256|ARBA:ARBA00022658};
KW   Reference proteome {ECO:0000313|Proteomes:UP000079721}.
FT   DOMAIN          52..442
FT                   /note="UDENN"
FT                   /evidence="ECO:0000259|PROSITE:PS50211"
FT   REGION          1..26
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   468 AA;  53353 MW;  CB80BF85640A2757 CRC64;
     MDGLGRRLRS SLRLKRGRGG PPQDNVGAAV KELERTPEYS LPNFTGGQHF FEYLLVVSLK
     KKRSGKDYEP TITYQFPKRE NLLRGQQEEE ERLLGAIPLF CFPDGNEWVP LTEYPRETFS
     FVLTNVDGSR KIGYCRRLLP AGSDPRLPRV YCIISCIGCF GLFSKILDEV EKRHQISMAV
     IYPFMQGLRE AAFPAPGKTV TLKSFIPDSG TEFISLTRPL DSHLEHVDFS SLLKCLRFEQ
     ILQIFASAVL ERRIIFLAED LSTLSQCIHA AAALLYPFNW AHTYIPVVPE SLLATVCCPT
     PFMVGVQMRF LQEVMDSPME EVLLVNLCDG TFLMSVGDEK DILPPKLQDD ILSSLGHQKG
     EFQPSEQINE HVSGPFVQFF VKTVGHYASY IKREANGQGH FQERAFYKAL HSKANRRFVK
     KFVKTQLFSL FIQEAEKSKN PPAGYFQQKI VEYEEQKKQK KSKEKTVK
//