ID A0A1S3A6E6_ERIEU Unreviewed; 533 AA.
AC A0A1S3A6E6;
DT 12-APR-2017, integrated into UniProtKB/TrEMBL.
DT 12-APR-2017, sequence version 1.
DT 27-MAR-2024, entry version 28.
DE SubName: Full=T-box transcription factor TBX21 {ECO:0000313|RefSeq:XP_007530073.1};
GN Name=TBX21 {ECO:0000313|RefSeq:XP_007530073.1};
OS Erinaceus europaeus (Western European hedgehog).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Laurasiatheria; Eulipotyphla; Erinaceidae; Erinaceinae;
OC Erinaceus.
OX NCBI_TaxID=9365 {ECO:0000313|Proteomes:UP000079721, ECO:0000313|RefSeq:XP_007530073.1};
RN [1] {ECO:0000313|RefSeq:XP_007530073.1}
RP IDENTIFICATION.
RG RefSeq;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|ARBA:ARBA00004123,
CC ECO:0000256|PROSITE-ProRule:PRU00201}.
CC -!- CAUTION: Lacks conserved residue(s) required for the propagation of
CC feature annotation. {ECO:0000256|PROSITE-ProRule:PRU00201}.
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DR RefSeq; XP_007530073.1; XM_007530011.2.
DR AlphaFoldDB; A0A1S3A6E6; -.
DR STRING; 9365.ENSEEUP00000008200; -.
DR GeneID; 103119690; -.
DR CTD; 30009; -.
DR eggNOG; KOG3585; Eukaryota.
DR InParanoid; A0A1S3A6E6; -.
DR OrthoDB; 5323209at2759; -.
DR Proteomes; UP000079721; Unplaced.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0003700; F:DNA-binding transcription factor activity; IEA:InterPro.
DR GO; GO:0000978; F:RNA polymerase II cis-regulatory region sequence-specific DNA binding; IEA:InterPro.
DR GO; GO:0045893; P:positive regulation of DNA-templated transcription; IEA:InterPro.
DR CDD; cd20203; T-box_TBX21; 1.
DR Gene3D; 2.60.40.820; Transcription factor, T-box; 1.
DR InterPro; IPR008967; p53-like_TF_DNA-bd_sf.
DR InterPro; IPR046360; T-box_DNA-bd.
DR InterPro; IPR036960; T-box_sf.
DR InterPro; IPR001699; TF_T-box.
DR InterPro; IPR018186; TF_T-box_CS.
DR PANTHER; PTHR11267; T-BOX PROTEIN-RELATED; 1.
DR PANTHER; PTHR11267:SF125; T-BOX TRANSCRIPTION FACTOR TBX21; 1.
DR Pfam; PF00907; T-box; 1.
DR PRINTS; PR00937; TBOX.
DR SMART; SM00425; TBOX; 1.
DR SUPFAM; SSF49417; p53-like transcription factors; 1.
DR PROSITE; PS01283; TBOX_1; 1.
DR PROSITE; PS01264; TBOX_2; 1.
DR PROSITE; PS50252; TBOX_3; 1.
PE 4: Predicted;
KW DNA-binding {ECO:0000256|ARBA:ARBA00023125, ECO:0000256|PROSITE-
KW ProRule:PRU00201};
KW Nucleus {ECO:0000256|ARBA:ARBA00023242, ECO:0000256|PROSITE-
KW ProRule:PRU00201}; Reference proteome {ECO:0000313|Proteomes:UP000079721};
KW Transcription {ECO:0000256|ARBA:ARBA00023163};
KW Transcription regulation {ECO:0000256|ARBA:ARBA00023015}.
FT DOMAIN 139..324
FT /note="T-box"
FT /evidence="ECO:0000259|PROSITE:PS50252"
FT REGION 1..52
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 447..533
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 533 AA; 58298 MW; 84F97F6A64124C0C CRC64;
MGIVEPDCGD MLTGTEPMPA SDEGRAPGAD PHNRYFYPEP GAQDDRRGAA GLGAPYTGGA
LVPAAPGRFL GAYSYPPRPQ AAGFPGPAEP FPPAAGAEGY PAADSFAAPD PRAGLYAGPR
EDYALPAGLE VSGKLRVALN NHLLWSKFNQ HQTEMIITKQ GRRMFPFLSF TVAGLEPTSH
YRMFVDVVLV DQHHWRYQSG KWVQCGKAEG SMPGNRLYVH PDSPNTGAHW MRQEVSFGKL
KLTNNKGASN NVTQMIVLQS LHKYQPRLHI VEVNDNEPEV ACNASNAHIF TFQETQFIAV
TAYQNAEITQ LKIDNNPFAK GFRENFESMY ASVDTSVPSP PGPNCQFLGG DHYSPLLPNQ
YSVPSRFYPD LPAQAKDVVP QSYWLGTPRD HSYEAEFRAV SMKPAFLPST PGPTMSYYRG
QEVLAPGASW PMAPQYPPKM SPASWFRPMR TLPMEPGPGV PEGRGPEDQG PHSVWTEITP
LRSESSDSGL GEGDSKRRRV SPYPSSGDSS SPAGAPSPFD KEAEGQFYNY FPN
//
