ID A0A1S3A6K9_ERIEU Unreviewed; 735 AA.
AC A0A1S3A6K9;
DT 12-APR-2017, integrated into UniProtKB/TrEMBL.
DT 12-APR-2017, sequence version 1.
DT 27-MAR-2024, entry version 29.
DE SubName: Full=E3 ubiquitin-protein ligase TRIM33 isoform X3 {ECO:0000313|RefSeq:XP_007530241.1};
GN Name=TRIM33 {ECO:0000313|RefSeq:XP_007530241.1};
OS Erinaceus europaeus (Western European hedgehog).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Laurasiatheria; Eulipotyphla; Erinaceidae; Erinaceinae;
OC Erinaceus.
OX NCBI_TaxID=9365 {ECO:0000313|Proteomes:UP000079721, ECO:0000313|RefSeq:XP_007530241.1};
RN [1] {ECO:0000313|RefSeq:XP_007530241.1}
RP IDENTIFICATION.
RG RefSeq;
RL Submitted (NOV-2023) to UniProtKB.
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DR RefSeq; XP_007530241.1; XM_007530179.2.
DR AlphaFoldDB; A0A1S3A6K9; -.
DR STRING; 9365.ENSEEUP00000004806; -.
DR CTD; 51592; -.
DR eggNOG; KOG2177; Eukaryota.
DR OrthoDB; 56754at2759; -.
DR Proteomes; UP000079721; Unplaced.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR CDD; cd05502; Bromo_tif1_like; 1.
DR CDD; cd15624; PHD_TIF1gamma; 1.
DR Gene3D; 1.20.920.10; Bromodomain-like; 1.
DR Gene3D; 3.30.40.10; Zinc/RING finger domain, C3HC4 (zinc finger); 1.
DR InterPro; IPR001487; Bromodomain.
DR InterPro; IPR036427; Bromodomain-like_sf.
DR InterPro; IPR019786; Zinc_finger_PHD-type_CS.
DR InterPro; IPR011011; Znf_FYVE_PHD.
DR InterPro; IPR001965; Znf_PHD.
DR InterPro; IPR019787; Znf_PHD-finger.
DR InterPro; IPR013083; Znf_RING/FYVE/PHD.
DR PANTHER; PTHR45915:SF3; E3 UBIQUITIN-PROTEIN LIGASE TRIM33; 1.
DR PANTHER; PTHR45915; TRANSCRIPTION INTERMEDIARY FACTOR; 1.
DR Pfam; PF00439; Bromodomain; 1.
DR Pfam; PF00628; PHD; 1.
DR SMART; SM00297; BROMO; 1.
DR SMART; SM00249; PHD; 1.
DR SUPFAM; SSF47370; Bromodomain; 1.
DR SUPFAM; SSF57903; FYVE/PHD zinc finger; 1.
DR PROSITE; PS50014; BROMODOMAIN_2; 1.
DR PROSITE; PS01359; ZF_PHD_1; 1.
DR PROSITE; PS50016; ZF_PHD_2; 1.
PE 4: Predicted;
KW Bromodomain {ECO:0000256|PROSITE-ProRule:PRU00035};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Nucleus {ECO:0000256|ARBA:ARBA00023242};
KW Reference proteome {ECO:0000313|Proteomes:UP000079721};
KW Zinc {ECO:0000256|ARBA:ARBA00022833};
KW Zinc-finger {ECO:0000256|ARBA:ARBA00022771, ECO:0000256|PROSITE-
KW ProRule:PRU00146}.
FT DOMAIN 495..542
FT /note="PHD-type"
FT /evidence="ECO:0000259|PROSITE:PS50016"
FT DOMAIN 582..654
FT /note="Bromo"
FT /evidence="ECO:0000259|PROSITE:PS50014"
FT REGION 145..171
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 212..237
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 250..269
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 281..300
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 311..373
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 394..426
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 699..735
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 714..735
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 735 AA; 81230 MW; 94B40D423F3418DE CRC64;
MKLLQQQNDI TGLSRQVKHV MNFTNWAIAS GSSTALLYSK RLITFQLRHI LKARCDPVPA
ANGAIRFHCD PTFWAKNVVN LGNLVIESKP APGYTPNVVV GQVPPGTNHI SKTPGQINLA
QLRLQHMQQQ VYAQKHQQLQ QMRMQQPPAP VPTTTATTQQ HSRQAAPQML QQQPPRLISV
QTMQRSNMSC GAFQAHQMRL AQNAARIPGI PRHSGPQYSM MQPHLQRQHS NPGHAGPFPV
VSVHNTTINP TSPTTATMAN ANRGPTSPSV TAIELIPSVT NPENLPSLPD IPPIQLEDAG
SSSLDNLLSR YISGSHLPPQ PTSTMNPSPG PSALSPGSSG LPNSHTPVRP PSTSSTGSRG
SCGSSGRNVE KTSLSFKADQ VKVKQEPGTE DEICSFSGTV KQEKTEDGRR SACMLSSPES
SLTPPLSTNL HLESELDALT SLENHVKSEP TDMNESCKQS GLNSLVNGKS PIRSLMHRSA
RIGGDGNSKD DDPNEDWCAV CQNGGDLLCC EKCPKVFHLT CHVPTLLSFP SGDWICTFCR
DIGKPEVEYD CDNLQHSKKG KTAQGLSPMD QRKCERLLLY LYCHELSIEF QEPVPASIPN
YYKIIKKPMD LSTVKKKLQK KHSQHYQIPD DFVADVRLIF KNCERFNEMM KVVQVYAETQ
EINLKADSEV AQAGKAVALY FEDKLTEIYS DRTFAPLPEF EQEEDDGEVT EDSDEDFIQP
RRKRLKSDER PVHIK
//
