ID   A0A1S3A7J6_ERIEU        Unreviewed;       344 AA.
AC   A0A1S3A7J6;
DT   12-APR-2017, integrated into UniProtKB/TrEMBL.
DT   12-APR-2017, sequence version 1.
DT   27-MAR-2024, entry version 23.
DE   SubName: Full=Calcium homeostasis modulator protein 3 {ECO:0000313|RefSeq:XP_007530576.1};
GN   Name=CALHM3 {ECO:0000313|RefSeq:XP_007530576.1};
OS   Erinaceus europaeus (Western European hedgehog).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Laurasiatheria; Eulipotyphla; Erinaceidae; Erinaceinae;
OC   Erinaceus.
OX   NCBI_TaxID=9365 {ECO:0000313|Proteomes:UP000079721, ECO:0000313|RefSeq:XP_007530576.1};
RN   [1] {ECO:0000313|RefSeq:XP_007530576.1}
RP   IDENTIFICATION.
RG   RefSeq;
RL   Submitted (NOV-2023) to UniProtKB.
CC   -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC       pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC   -!- SIMILARITY: Belongs to the CALHM family.
CC       {ECO:0000256|ARBA:ARBA00008497}.
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DR   RefSeq; XP_007530576.1; XM_007530514.1.
DR   AlphaFoldDB; A0A1S3A7J6; -.
DR   STRING; 9365.ENSEEUP00000009871; -.
DR   GeneID; 103120148; -.
DR   CTD; 119395; -.
DR   eggNOG; ENOG502QRUK; Eukaryota.
DR   InParanoid; A0A1S3A7J6; -.
DR   OrthoDB; 5296902at2759; -.
DR   Proteomes; UP000079721; Unplaced.
DR   GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR   InterPro; IPR029569; CALHM.
DR   PANTHER; PTHR32261; CALCIUM HOMEOSTASIS MODULATOR PROTEIN; 1.
DR   PANTHER; PTHR32261:SF7; CALCIUM HOMEOSTASIS MODULATOR PROTEIN 3; 1.
DR   Pfam; PF14798; Ca_hom_mod; 1.
PE   3: Inferred from homology;
KW   Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW   Reference proteome {ECO:0000313|Proteomes:UP000079721};
KW   Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW   ECO:0000256|SAM:Phobius}; Transport {ECO:0000256|ARBA:ARBA00022448}.
FT   TRANSMEM        21..37
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        49..70
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        178..198
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
SQ   SEQUENCE   344 AA;  39082 MW;  1C3407F6D2C9707A CRC64;
     MDKFRMLFQH FQSSSESVMN GVCLLLAVVT VKLYSSFDFN CPCLERYNAL YGLGLLLTPP
     LALFLCGLLA NRQSVVLVEE WRRPPGHRRK DPGIIRYMCS SVLQRALAAP LVWVLLALLD
     GKCFVCAFSN SVDPGKFQDL ANMTPSQMQL FLAKVPCKED ELVKDSPARK AVSRYLRCLS
     QAIGWSVTLL LIVLAFLARC LRPCFDQTVF LQRRYWSNYV DLEQKLFDET CCEHARDFAH
     RCVLHFFASM QSEMRARALR WEGHARGHDH TPMPEPQEEL DAERGKAHLR AISSREQVDQ
     LLSTWYSRKP PLDLLAAPGL LGSSLSYRAP TVATDARLTQ HTDV
//