ID   A0A1S3A7K8_ERIEU        Unreviewed;       431 AA.
AC   A0A1S3A7K8;
DT   12-APR-2017, integrated into UniProtKB/TrEMBL.
DT   12-APR-2017, sequence version 1.
DT   27-MAR-2024, entry version 25.
DE   SubName: Full=E3 ubiquitin-protein ligase RNF128 isoform X1 {ECO:0000313|RefSeq:XP_007530676.1};
GN   Name=RNF128 {ECO:0000313|RefSeq:XP_007530676.1};
OS   Erinaceus europaeus (Western European hedgehog).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Laurasiatheria; Eulipotyphla; Erinaceidae; Erinaceinae;
OC   Erinaceus.
OX   NCBI_TaxID=9365 {ECO:0000313|Proteomes:UP000079721, ECO:0000313|RefSeq:XP_007530676.1};
RN   [1] {ECO:0000313|RefSeq:XP_007530676.1}
RP   IDENTIFICATION.
RG   RefSeq;
RL   Submitted (NOV-2023) to UniProtKB.
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DR   RefSeq; XP_007530676.1; XM_007530614.2.
DR   AlphaFoldDB; A0A1S3A7K8; -.
DR   GeneID; 103120237; -.
DR   CTD; 79589; -.
DR   eggNOG; KOG4628; Eukaryota.
DR   InParanoid; A0A1S3A7K8; -.
DR   OrthoDB; 5474929at2759; -.
DR   Proteomes; UP000079721; Unplaced.
DR   GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   CDD; cd02122; PA_GRAIL_like; 1.
DR   CDD; cd16802; RING-H2_RNF128-like; 1.
DR   Gene3D; 3.50.30.30; -; 1.
DR   Gene3D; 3.30.40.10; Zinc/RING finger domain, C3HC4 (zinc finger); 1.
DR   InterPro; IPR046450; PA_dom_sf.
DR   InterPro; IPR003137; PA_domain.
DR   InterPro; IPR001841; Znf_RING.
DR   InterPro; IPR013083; Znf_RING/FYVE/PHD.
DR   PANTHER; PTHR46539; E3 UBIQUITIN-PROTEIN LIGASE ATL42; 1.
DR   PANTHER; PTHR46539:SF2; RING FINGER PROTEIN 150 ISOFORM X1; 1.
DR   Pfam; PF02225; PA; 1.
DR   Pfam; PF13639; zf-RING_2; 1.
DR   SMART; SM00184; RING; 1.
DR   SUPFAM; SSF52025; PA domain; 1.
DR   SUPFAM; SSF57850; RING/U-box; 1.
DR   PROSITE; PS50089; ZF_RING_2; 1.
PE   4: Predicted;
KW   Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW   Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW   Reference proteome {ECO:0000313|Proteomes:UP000079721};
KW   Signal {ECO:0000256|SAM:SignalP};
KW   Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW   ECO:0000256|SAM:Phobius}; Zinc {ECO:0000256|ARBA:ARBA00022833};
KW   Zinc-finger {ECO:0000256|ARBA:ARBA00022771, ECO:0000256|PROSITE-
KW   ProRule:PRU00175}.
FT   SIGNAL          1..36
FT                   /evidence="ECO:0000256|SAM:SignalP"
FT   CHAIN           37..431
FT                   /evidence="ECO:0000256|SAM:SignalP"
FT                   /id="PRO_5010280703"
FT   TRANSMEM        209..231
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   DOMAIN          280..321
FT                   /note="RING-type"
FT                   /evidence="ECO:0000259|PROSITE:PS50089"
FT   REGION          350..389
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          406..431
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   431 AA;  46956 MW;  115F04461F5E5716 CRC64;
     MGPRPGAGGS CRGSCGFSRL SVWCFLLALS PHPLCSRSAE AVWTAYLNVS WRVPNTGVNR
     TVWELSEEGV YGQDSPLEPV AGVLVPPDGP GALNACSPHT NFTVPMVPGS WSSTSQVSWL
     ALIQRGGGCT FADKIHLAYE RGASGAVIFN FAGTRNEVIP MSHPGAKDIV AIMIGNLRGT
     KILQSIQRGI QVTMVIEVGK KHGPWVNHYS IFFVSVSFFI ITAATVGYFI FYSARRLRNA
     RAQSRKQRQL KADAKKAIGR LKLRTLKQGD KEIGPDGDSC AVCIELYKPN DLVRILTCNH
     IFHKACVDPW LLEHRTCPMC KCDILKALGI EVDVEDGSMS LQVPVSNEIP NSASLHEEDN
     RSETASSGYA SVQGADEPPL EEHVPSANEN LQLVNHEANS LAVDVVPHVD NPTFEEDETP
     DQETAVREIK T
//