ID   A0A1S3A955_ERIEU        Unreviewed;       364 AA.
AC   A0A1S3A955;
DT   12-APR-2017, integrated into UniProtKB/TrEMBL.
DT   12-APR-2017, sequence version 1.
DT   27-MAR-2024, entry version 22.
DE   SubName: Full=Protein RIC-3 isoform X3 {ECO:0000313|RefSeq:XP_007531276.1};
GN   Name=RIC3 {ECO:0000313|RefSeq:XP_007531276.1};
OS   Erinaceus europaeus (Western European hedgehog).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Laurasiatheria; Eulipotyphla; Erinaceidae; Erinaceinae;
OC   Erinaceus.
OX   NCBI_TaxID=9365 {ECO:0000313|Proteomes:UP000079721, ECO:0000313|RefSeq:XP_007531276.1};
RN   [1] {ECO:0000313|RefSeq:XP_007531276.1}
RP   IDENTIFICATION.
RG   RefSeq;
RL   Submitted (NOV-2023) to UniProtKB.
CC   -!- SIMILARITY: Belongs to the ric-3 family.
CC       {ECO:0000256|ARBA:ARBA00008538}.
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DR   RefSeq; XP_007531276.1; XM_007531214.1.
DR   AlphaFoldDB; A0A1S3A955; -.
DR   CTD; 79608; -.
DR   OrthoDB; 5355665at2759; -.
DR   Proteomes; UP000079721; Unplaced.
DR   GO; GO:0005783; C:endoplasmic reticulum; IEA:UniProtKB-KW.
DR   GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR   InterPro; IPR026160; Ric3.
DR   InterPro; IPR032763; RIC3_N.
DR   PANTHER; PTHR21723:SF1; PROTEIN RIC-3; 1.
DR   PANTHER; PTHR21723; RESISTANCE TO INHIBITORS OF CHOLINESTERASE PROTEIN 3 RIC3; 1.
DR   Pfam; PF15361; RIC3; 1.
PE   3: Inferred from homology;
KW   Coiled coil {ECO:0000256|SAM:Coils};
KW   Endoplasmic reticulum {ECO:0000256|ARBA:ARBA00022824};
KW   Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW   Reference proteome {ECO:0000313|Proteomes:UP000079721};
KW   Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW   ECO:0000256|SAM:Phobius}.
FT   TRANSMEM        95..116
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   DOMAIN          15..166
FT                   /note="Resistance to inhibitors of cholinesterase protein 3
FT                   N-terminal"
FT                   /evidence="ECO:0000259|Pfam:PF15361"
FT   REGION          31..66
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          337..364
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COILED          140..167
FT                   /evidence="ECO:0000256|SAM:Coils"
SQ   SEQUENCE   364 AA;  40265 MW;  06E10F0A99B9F724 CRC64;
     MAYSAVQRVA LGSGLVLAVS LLLPKAFLSR GRRQEPPSTP AGKLGRFPPM MHHHQAPSDG
     QTPGARFQRS HIAEAFTKAK GSAGSTGGGG SGRGLMGQII PIYGFGIFLY ILYILFKLSK
     GKSATEDRKC STATPGNSRR KITNFELVQL QEKLKETEEA MEKLINGVGP NGERAQTVTS
     DQEKQLLHQL REITRAMKEG KFIDRSTPEK EAEEAPYMED WEGYPEETYP LYDISDCIKH
     RQETILVDYP NPKEPSAEEI AEGVGVLEEP EHLGWQTPTD TRPQEDNSVV ASYDPKSETC
     SCCLHEEEDP AVLAENCGFS ADSEQEEATK EVWPRDIREE GLGTSSDEAY TGSMLRKRNL
     QALE
//