ID   A0A1S3ABC3_ERIEU        Unreviewed;       937 AA.
AC   A0A1S3ABC3;
DT   12-APR-2017, integrated into UniProtKB/TrEMBL.
DT   12-APR-2017, sequence version 1.
DT   27-MAR-2024, entry version 31.
DE   SubName: Full=Matrilin-2 isoform X3 {ECO:0000313|RefSeq:XP_007532343.1};
GN   Name=MATN2 {ECO:0000313|RefSeq:XP_007532343.1};
OS   Erinaceus europaeus (Western European hedgehog).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Laurasiatheria; Eulipotyphla; Erinaceidae; Erinaceinae;
OC   Erinaceus.
OX   NCBI_TaxID=9365 {ECO:0000313|Proteomes:UP000079721, ECO:0000313|RefSeq:XP_007532343.1};
RN   [1] {ECO:0000313|RefSeq:XP_007532343.1}
RP   IDENTIFICATION.
RG   RefSeq;
RL   Submitted (NOV-2023) to UniProtKB.
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DR   RefSeq; XP_007532343.1; XM_007532281.2.
DR   AlphaFoldDB; A0A1S3ABC3; -.
DR   GeneID; 103121738; -.
DR   CTD; 4147; -.
DR   OrthoDB; 1453590at2759; -.
DR   Proteomes; UP000079721; Unplaced.
DR   GO; GO:0005509; F:calcium ion binding; IEA:InterPro.
DR   CDD; cd00054; EGF_CA; 3.
DR   CDD; cd01475; vWA_Matrilin; 1.
DR   Gene3D; 1.20.5.30; -; 1.
DR   Gene3D; 2.10.25.10; Laminin; 10.
DR   Gene3D; 3.40.50.410; von Willebrand factor, type A domain; 2.
DR   InterPro; IPR001881; EGF-like_Ca-bd_dom.
DR   InterPro; IPR000742; EGF-like_dom.
DR   InterPro; IPR000152; EGF-type_Asp/Asn_hydroxyl_site.
DR   InterPro; IPR009030; Growth_fac_rcpt_cys_sf.
DR   InterPro; IPR036337; Matrilin_cc_sf.
DR   InterPro; IPR019466; Matrilin_coiled-coil_trimer.
DR   InterPro; IPR002035; VWF_A.
DR   InterPro; IPR036465; vWFA_dom_sf.
DR   PANTHER; PTHR24020; COLLAGEN ALPHA; 1.
DR   PANTHER; PTHR24020:SF35; MATRILIN-2; 1.
DR   Pfam; PF07645; EGF_CA; 1.
DR   Pfam; PF14670; FXa_inhibition; 8.
DR   Pfam; PF10393; Matrilin_ccoil; 1.
DR   Pfam; PF00092; VWA; 2.
DR   PRINTS; PR00453; VWFADOMAIN.
DR   SMART; SM00181; EGF; 10.
DR   SMART; SM00179; EGF_CA; 10.
DR   SMART; SM01279; Matrilin_ccoil; 1.
DR   SMART; SM00327; VWA; 2.
DR   SUPFAM; SSF58002; Chicken cartilage matrix protein; 1.
DR   SUPFAM; SSF57184; Growth factor receptor domain; 4.
DR   SUPFAM; SSF53300; vWA-like; 2.
DR   PROSITE; PS00010; ASX_HYDROXYL; 3.
DR   PROSITE; PS01186; EGF_2; 8.
DR   PROSITE; PS50234; VWFA; 2.
PE   4: Predicted;
KW   Coiled coil {ECO:0000256|ARBA:ARBA00023054, ECO:0000256|SAM:Coils};
KW   Disulfide bond {ECO:0000256|ARBA:ARBA00023157};
KW   EGF-like domain {ECO:0000256|ARBA:ARBA00022536};
KW   Glycoprotein {ECO:0000256|ARBA:ARBA00023180};
KW   Reference proteome {ECO:0000313|Proteomes:UP000079721};
KW   Repeat {ECO:0000256|ARBA:ARBA00022737}; Signal {ECO:0000256|SAM:SignalP}.
FT   SIGNAL          1..23
FT                   /evidence="ECO:0000256|SAM:SignalP"
FT   CHAIN           24..937
FT                   /evidence="ECO:0000256|SAM:SignalP"
FT                   /id="PRO_5010171532"
FT   DOMAIN          57..236
FT                   /note="VWFA"
FT                   /evidence="ECO:0000259|PROSITE:PS50234"
FT   DOMAIN          655..830
FT                   /note="VWFA"
FT                   /evidence="ECO:0000259|PROSITE:PS50234"
FT   REGION          838..858
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COILED          906..933
FT                   /evidence="ECO:0000256|SAM:Coils"
SQ   SEQUENCE   937 AA;  104823 MW;  D41E73F0487543FB CRC64;
     MEKMLVGCFL LILGQVVLLP AEARKRLPAR STPRGRPTRT HPQMGLLESS CENKRADLVF
     IIDSSRSVNT QDYAKVKEFI VDILQFLDIG PEVTRVGLLQ YGSTVKNEFS LKTFKRKSEV
     ERAVKRMRHL STGTMTGLAI QYALNIAFSE AEGARPLRDN VPRVIMIVTD GRPQDSVAEV
     AAKARDTGIL IFAIGVGQVD FNTLKAIGSE PHEDHVFLVA NFSQIESLTS VFQNKLCTVH
     MCSVLEHNCV HFCINTPGSY ICRCKQGYIL NSDQKTCRIQ DLCAVEDHGC EQLCVNVLSS
     YVCQCYNGYT LAKDGKSCDA VDYCASENHG CQHECVNGDG SYFCKCPKGF ALNPDKKTCT
     KIDYCASSNH GCQHECVNTD DSYSCRCLKG FILSPDKKTC RRINYCALNK PGCEHECVNT
     EEGFFCRCHQ GYTLDTNGRT CSRVDHCATQ DHGCEQLCLN TGDSYVCQCS EGFLINEDLK
     TCFRVDYCLL SEHGCEYSCI NTDRSFACQC PEGHTLRSDG KTCAKMDSCA LGDHGCEHSC
     VSSEDSYVCQ CFEGYLLRED GKTCKRKDIC QAVDHGCEHI CVSSDKSYIC KCLEGFWLAE
     DGKHCRWKDV CKSTQHGCEH ICVNHGNSYS CKCSEGFVLA EDGRRCKRCT EGPIDLVFVI
     DGSKSLGEEN FETVKQFVTR IIDSLAISPK AARVGLLQYS TQVRTEFSLN SFSSAKDMKK
     AVAHMKYMGK GSMTGLALKH MFERSFAQME GARPLSSRVP RVAVVFTDGR AQDDVSEWAS
     KAKTNGITMY AVGIGKAIEE ELQEIASEPT EKHLFYAEDF STMGEISEKL KKGICEALED
     SDGSQDSPAR ELPKRVQQPT VQHRYLFEED SLSRTTQKLS HLTKSSGIPL EEKHDQCKCE
     NLIMFQNLAN EEVRKLTQRL EEMTQRMEAL ENRLRYR
//