ID A0A1S3ACX2_ERIEU Unreviewed; 535 AA.
AC A0A1S3ACX2;
DT 12-APR-2017, integrated into UniProtKB/TrEMBL.
DT 12-APR-2017, sequence version 1.
DT 27-MAR-2024, entry version 25.
DE SubName: Full=Carcinoembryonic antigen-related cell adhesion molecule 1-like isoform X1 {ECO:0000313|RefSeq:XP_007533011.2};
GN Name=LOC103122354 {ECO:0000313|RefSeq:XP_007533011.2};
OS Erinaceus europaeus (Western European hedgehog).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Laurasiatheria; Eulipotyphla; Erinaceidae; Erinaceinae;
OC Erinaceus.
OX NCBI_TaxID=9365 {ECO:0000313|Proteomes:UP000079721, ECO:0000313|RefSeq:XP_007533011.2};
RN [1] {ECO:0000313|RefSeq:XP_007533011.2}
RP IDENTIFICATION.
RG RefSeq;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SIMILARITY: Belongs to the immunoglobulin superfamily. CEA family.
CC {ECO:0000256|ARBA:ARBA00038222}.
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DR RefSeq; XP_007533011.2; XM_007532949.2.
DR AlphaFoldDB; A0A1S3ACX2; -.
DR GeneID; 103122354; -.
DR CTD; 634; -.
DR eggNOG; ENOG502RXPD; Eukaryota.
DR InParanoid; A0A1S3ACX2; -.
DR OrthoDB; 3033616at2759; -.
DR Proteomes; UP000079721; Unplaced.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR CDD; cd20948; IgC2_CEACAM5-like; 1.
DR CDD; cd05740; IgI_hCEACAM_2_4_6_like; 1.
DR CDD; cd05774; IgV_CEACAM_D1; 1.
DR CDD; cd12087; TM_EGFR-like; 1.
DR Gene3D; 2.60.40.10; Immunoglobulins; 4.
DR InterPro; IPR007110; Ig-like_dom.
DR InterPro; IPR036179; Ig-like_dom_sf.
DR InterPro; IPR013783; Ig-like_fold.
DR InterPro; IPR003599; Ig_sub.
DR InterPro; IPR003598; Ig_sub2.
DR InterPro; IPR013106; Ig_V-set.
DR PANTHER; PTHR44427:SF1; CARCINOEMBRYONIC ANTIGEN-RELATED CELL ADHESION MOLECULE 1; 1.
DR PANTHER; PTHR44427; CARCINOEMBRYONIC ANTIGEN-RELATED CELL ADHESION MOLECULE 19; 1.
DR Pfam; PF13895; Ig_2; 1.
DR Pfam; PF13927; Ig_3; 2.
DR Pfam; PF07686; V-set; 1.
DR SMART; SM00409; IG; 4.
DR SMART; SM00408; IGc2; 3.
DR SUPFAM; SSF48726; Immunoglobulin; 3.
DR PROSITE; PS50835; IG_LIKE; 3.
PE 3: Inferred from homology;
KW Membrane {ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000079721};
KW Signal {ECO:0000256|SAM:SignalP}; Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT SIGNAL 1..34
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 35..535
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5010309962"
FT TRANSMEM 439..462
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 158..247
FT /note="Ig-like"
FT /evidence="ECO:0000259|PROSITE:PS50835"
FT DOMAIN 252..330
FT /note="Ig-like"
FT /evidence="ECO:0000259|PROSITE:PS50835"
FT DOMAIN 340..424
FT /note="Ig-like"
FT /evidence="ECO:0000259|PROSITE:PS50835"
FT REGION 471..535
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 473..504
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 535 AA; 58493 MW; C581FF1979FB1801 CRC64;
MVPPSAPSHR GSVPWKGLLL AVSLITFWTP PTTTQLTVKS VPANRTAPLT VESAPANAAE
GEDVLLLVHN RPENTIGFSW FKGESVESAH QIAGYEIATQ QTTTGPAHSG RETLYTNGSL
LFQNVRKNDT GFYTLHVIKS GLQIETVIGQ FHVFEDLSKV NFTITSNNSS PVEHSDTVVL
TCDSKIQDTT YLWFINNHSL PGSARLELSK DNRTLTLFHV TRNDTGPYEC EVQNLVSAHR
SDPLTLNVLY GPDAPTISPP DSYYLEGAAL NLSCQAASNP PAQYFWFFNG ELQQSTQMFF
IASLAMNNSG NYTCLANNSD TGLNNHTVKT IQALEPVTKP SIQTYNITVT ENDVVNLTCL
TNDIGVSILW FFNQLSLPLT ERMKLSQGNS TLTIKPIRRE DTGDYHCMVT NPVSFNKSDT
LKLVVKYNPE LHSGLSAGAI AGIVIGVLAG VALIAALVYF LYLRKTGGAS DHHQLSEQKP
SASNNSQDHS DNPPNKSDEV TYSILNFNGL EAKKPTSPPP FPISTEAVYS EVKKK
//
