ID A0A1S3ADZ6_ERIEU Unreviewed; 2064 AA.
AC A0A1S3ADZ6;
DT 12-APR-2017, integrated into UniProtKB/TrEMBL.
DT 12-APR-2017, sequence version 1.
DT 27-MAR-2024, entry version 28.
DE SubName: Full=CUB and sushi domain-containing protein 3 {ECO:0000313|RefSeq:XP_007533587.1};
GN Name=CSMD3 {ECO:0000313|RefSeq:XP_007533587.1};
OS Erinaceus europaeus (Western European hedgehog).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Laurasiatheria; Eulipotyphla; Erinaceidae; Erinaceinae;
OC Erinaceus.
OX NCBI_TaxID=9365 {ECO:0000313|Proteomes:UP000079721, ECO:0000313|RefSeq:XP_007533587.1};
RN [1] {ECO:0000313|RefSeq:XP_007533587.1}
RP IDENTIFICATION.
RG RefSeq;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- CAUTION: Lacks conserved residue(s) required for the propagation of
CC feature annotation. {ECO:0000256|PROSITE-ProRule:PRU00302}.
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DR RefSeq; XP_007533587.1; XM_007533525.2.
DR STRING; 9365.ENSEEUP00000009372; -.
DR CTD; 114788; -.
DR eggNOG; KOG4297; Eukaryota.
DR InParanoid; A0A1S3ADZ6; -.
DR OrthoDB; 5400609at2759; -.
DR Proteomes; UP000079721; Unplaced.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR CDD; cd00033; CCP; 19.
DR CDD; cd00041; CUB; 4.
DR Gene3D; 2.10.70.10; Complement Module, domain 1; 19.
DR Gene3D; 2.60.120.290; Spermadhesin, CUB domain; 6.
DR InterPro; IPR000859; CUB_dom.
DR InterPro; IPR035914; Sperma_CUB_dom_sf.
DR InterPro; IPR035976; Sushi/SCR/CCP_sf.
DR InterPro; IPR000436; Sushi_SCR_CCP_dom.
DR PANTHER; PTHR45656:SF9; CUB AND SUSHI DOMAIN-CONTAINING PROTEIN 3; 1.
DR PANTHER; PTHR45656; PROTEIN CBR-CLEC-78; 1.
DR Pfam; PF00431; CUB; 5.
DR Pfam; PF00084; Sushi; 19.
DR SMART; SM00032; CCP; 19.
DR SMART; SM00042; CUB; 5.
DR SUPFAM; SSF57535; Complement control module/SCR domain; 19.
DR SUPFAM; SSF49854; Spermadhesin, CUB domain; 5.
DR PROSITE; PS01180; CUB; 5.
DR PROSITE; PS50923; SUSHI; 19.
PE 4: Predicted;
KW Disulfide bond {ECO:0000256|ARBA:ARBA00023157, ECO:0000256|PROSITE-
KW ProRule:PRU00302}; Membrane {ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000079721};
KW Sushi {ECO:0000256|PROSITE-ProRule:PRU00302};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 1988..2009
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 2..227
FT /note="CUB"
FT /evidence="ECO:0000259|PROSITE:PS01180"
FT DOMAIN 233..294
FT /note="Sushi"
FT /evidence="ECO:0000259|PROSITE:PS50923"
FT DOMAIN 296..404
FT /note="CUB"
FT /evidence="ECO:0000259|PROSITE:PS01180"
FT DOMAIN 407..466
FT /note="Sushi"
FT /evidence="ECO:0000259|PROSITE:PS50923"
FT DOMAIN 468..576
FT /note="CUB"
FT /evidence="ECO:0000259|PROSITE:PS01180"
FT DOMAIN 579..638
FT /note="Sushi"
FT /evidence="ECO:0000259|PROSITE:PS50923"
FT DOMAIN 640..751
FT /note="CUB"
FT /evidence="ECO:0000259|PROSITE:PS01180"
FT DOMAIN 750..811
FT /note="Sushi"
FT /evidence="ECO:0000259|PROSITE:PS50923"
FT DOMAIN 813..924
FT /note="CUB"
FT /evidence="ECO:0000259|PROSITE:PS01180"
FT DOMAIN 924..986
FT /note="Sushi"
FT /evidence="ECO:0000259|PROSITE:PS50923"
FT DOMAIN 987..1048
FT /note="Sushi"
FT /evidence="ECO:0000259|PROSITE:PS50923"
FT DOMAIN 1049..1113
FT /note="Sushi"
FT /evidence="ECO:0000259|PROSITE:PS50923"
FT DOMAIN 1114..1171
FT /note="Sushi"
FT /evidence="ECO:0000259|PROSITE:PS50923"
FT DOMAIN 1172..1229
FT /note="Sushi"
FT /evidence="ECO:0000259|PROSITE:PS50923"
FT DOMAIN 1230..1287
FT /note="Sushi"
FT /evidence="ECO:0000259|PROSITE:PS50923"
FT DOMAIN 1288..1349
FT /note="Sushi"
FT /evidence="ECO:0000259|PROSITE:PS50923"
FT DOMAIN 1350..1407
FT /note="Sushi"
FT /evidence="ECO:0000259|PROSITE:PS50923"
FT DOMAIN 1411..1468
FT /note="Sushi"
FT /evidence="ECO:0000259|PROSITE:PS50923"
FT DOMAIN 1469..1527
FT /note="Sushi"
FT /evidence="ECO:0000259|PROSITE:PS50923"
FT DOMAIN 1528..1587
FT /note="Sushi"
FT /evidence="ECO:0000259|PROSITE:PS50923"
FT DOMAIN 1588..1645
FT /note="Sushi"
FT /evidence="ECO:0000259|PROSITE:PS50923"
FT DOMAIN 1646..1703
FT /note="Sushi"
FT /evidence="ECO:0000259|PROSITE:PS50923"
FT DOMAIN 1707..1765
FT /note="Sushi"
FT /evidence="ECO:0000259|PROSITE:PS50923"
FT DOMAIN 1766..1825
FT /note="Sushi"
FT /evidence="ECO:0000259|PROSITE:PS50923"
FT DISULFID 1142..1169
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00302"
FT DISULFID 1200..1227
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00302"
FT DISULFID 1258..1285
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00302"
FT DISULFID 1320..1347
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00302"
FT DISULFID 1378..1405
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00302"
FT DISULFID 1439..1466
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00302"
FT DISULFID 1498..1525
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00302"
FT DISULFID 1616..1643
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00302"
FT DISULFID 1674..1701
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00302"
FT DISULFID 1736..1763
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00302"
FT NON_TER 1
FT /evidence="ECO:0000313|RefSeq:XP_007533587.1"
SQ SEQUENCE 2064 AA; 224833 MW; A90A4FFC6D00D871 CRC64;
PCGSRSTGSE GTVLSPTYPK NYSVGHNCVY SIAVPKEFVS SIDSQKTKFK DQKTWAFFHA
RNDDSCSQRT ALADPQTCYY PGLVPQSEQY SYLPNSLGIG AFLLKLKVPM KNEAALDAMW
NLGLDPMEQI AMENLMELIG SLELLETANV DFAVRVVFGQ FVFFQTSLHD VVEVYDGPTQ
QSSLLSSLSG SHSGESLPLS SGNQITIRFT SVGPITAKGF HFVYQAVPRT SSTQCSSVPE
PRFGRRIGNE FAVGSLVLFE CNPGYILHGS VAIRCDTVPN SLAQWNDSLP TCIVPCGGIL
TKRKGTILSP GYPEPYDNNL NCVWKITVPE GAGIQVQVVS FATEHNWDSL DFYDGGDNNA
PRLGSYSGTT IPHLLNSTSN NLYLNFQSDI SVSAAGFHLE YTAIGLDSCP EPQTPSSGVK
VGDRYMVGDV VSFQCDQGYS LQGHSHITCM PGPVRRWNYP IPICLAQCGG AMSDFSGVIL
SPGFPGNYPS SLDCTWTIKL PIGFGVHIQF VNFSTETIHD YLEVRSGSTE TSSVIGRLSG
PQIPSSLFST THETSLYFHS DYSQNKQGFH IVYQAYQLQS CPDPRPFRNG FVIGSDFTVG
QTISFDCFPG YTLIGNSALT CLHGVSRNWN HPLPRCEALC GGNITAMNGT IYSPGYPDEY
PNFQDCFWLV RVPPGNGIYI NFTVLQTEPI YDFITVWDGP DQNSPQIGQF SGNTALESVY
STSNQILIKF HSDFTTSGFF VLSYHAYQLR VCQPPPPVPN AEILTEDDEF EIGDIIRYQC
LPGFTLVGNA ILTCRLGERL QMDGAPPVCQ VLCPANELRL DSTGVILSPG YPDSYPNLQM
CAWSISVEKG YNISMFVEFF QTEKEFDVLQ VYDGPNIQSP VLISLSGDYS SAFNITSNGH
EVFLQWSADH GNNKKGFRIR YIAFYCSTPE SPPHGYIISQ TGGQLNSVVR WACDRGFRLV
GKSSAVCRKS SYGFHAWDAP VPACQAISCG IPKAPANGGI LTTDYLVGTR VTYFCNDGYR
LSSKELTTAV CQSDGTWSNH NKTPRCVVVT CPSINSFTLE HGRWRIVNGS HYEYKTKVVF
SCDPGYHGLG PASIECLPNG TWSWRNERPY CQIISCGELP TPPNGNKIGT QTSYGSTAIF
TCDLGFMLVG SAVRECLSSG LWSGSETRCL AGHCGIPEFI VNGQVIGENY GYRDTVVYQC
NPGFRLIGSS VRICQQDHNW SGQLPSCVPI SCGHPGSPIY GRTSGNGFNF NDVVTFSCNI
GYLMQGPTKA QCQANRQWSH PPPMCKVVNC SDPGIPANSK RESKIEHGNF TYGTVVFYDC
NPGYFLFGSS VLICQPNGQW DKPLPECIMI DCGHPGIPPN AVLSGEKYTF GSTVHYSCTG
KRALLGQSSR TCQLNGHWSG SQPHCSGDAT GICGDPGTPG HGSRQESDFR TKSSVRFACD
IGYILHGSEE RTCLANGSWT GRQPECKAVQ CGNPGTTANG KVFRIDGTTF SSSVIYSCAE
GYILSGPSVR QCTANGTWSG TLPNCTIISC GDPGIPANGL RYGDDYVVGQ NVSYMCQPGY
TMELNGSRSR TCTTNGTWNG VMPTCRAVTC STPPQISNGR LEGTNFDWGF SISYICSPGY
ELSFPAVLTC VGNGTWSGEV PQCLPKFCGD PGIPTHGKRE GKSFIYQSEV SFSCNSPFIL
VGSSTRICQA DGTWSGSSPH CIEPTRTSCE NPGVPRHGSQ NNTFGFQVGN VVQFHCKKGH
LLQGSTTRTC LPDLTWSGIQ PECIPHSCKQ PETPAHANVV GMDLPSHGYT LIYTCQPGFF
LAGGTEHRVC RSDNTWTGKV PVCEAGSKLL VKDPRPALGT PSPKLSVPDD VFAQNYIWKG
SYNFKGRKQP MTLTVTSFNA STGRVNATLS NSNMELLLSG VYKSQEARLM LHIYLIKAPA
HSSVKRMKEE NWAMDGFVSA EPDGATYVFQ GFIQGKDYGQ FGLQRLGLNM SEGSNSLNQP
HGTNSSSVAI AILVPFFALI FAGFGFYLYK QRTAPKTQYT GCSVHENNNG QAAFENPMYD
TNAKSVEGKA VRFDPNLNTV CTMV
//
