ID   A0A1S3AEP8_ERIEU        Unreviewed;       890 AA.
AC   A0A1S3AEP8;
DT   12-APR-2017, integrated into UniProtKB/TrEMBL.
DT   12-APR-2017, sequence version 1.
DT   27-MAR-2024, entry version 24.
DE   RecName: Full=NEDD4-binding protein 1 {ECO:0000256|ARBA:ARBA00039336};
GN   Name=N4BP1 {ECO:0000313|RefSeq:XP_007533737.1};
OS   Erinaceus europaeus (Western European hedgehog).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Laurasiatheria; Eulipotyphla; Erinaceidae; Erinaceinae;
OC   Erinaceus.
OX   NCBI_TaxID=9365 {ECO:0000313|Proteomes:UP000079721, ECO:0000313|RefSeq:XP_007533737.1};
RN   [1] {ECO:0000313|RefSeq:XP_007533737.1}
RP   IDENTIFICATION.
RG   RefSeq;
RL   Submitted (NOV-2023) to UniProtKB.
CC   -!- SUBCELLULAR LOCATION: Nucleus, PML body
CC       {ECO:0000256|ARBA:ARBA00004322}. Nucleus, nucleolus
CC       {ECO:0000256|ARBA:ARBA00004604}.
CC   -!- SIMILARITY: Belongs to the N4BP1 family.
CC       {ECO:0000256|ARBA:ARBA00038274}.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   RefSeq; XP_007533737.1; XM_007533675.2.
DR   AlphaFoldDB; A0A1S3AEP8; -.
DR   GeneID; 103123045; -.
DR   CTD; 9683; -.
DR   eggNOG; KOG3777; Eukaryota.
DR   InParanoid; A0A1S3AEP8; -.
DR   OrthoDB; 180910at2759; -.
DR   Proteomes; UP000079721; Unplaced.
DR   GO; GO:0005730; C:nucleolus; IEA:UniProtKB-SubCell.
DR   GO; GO:0003723; F:RNA binding; IEA:InterPro.
DR   CDD; cd22476; KH-I_N4BP1; 1.
DR   CDD; cd09032; KH-I_N4BP1_like_rpt1; 1.
DR   CDD; cd18728; PIN_N4BP1-like; 1.
DR   Gene3D; 3.40.50.11980; -; 1.
DR   InterPro; IPR036612; KH_dom_type_1_sf.
DR   InterPro; IPR021869; RNase_Zc3h12_NYN.
DR   PANTHER; PTHR12876; N4BP1-RELATED; 1.
DR   PANTHER; PTHR12876:SF26; NEDD4-BINDING PROTEIN 1; 1.
DR   Pfam; PF11977; RNase_Zc3h12a; 1.
DR   SUPFAM; SSF54791; Eukaryotic type KH-domain (KH-domain type I); 1.
PE   3: Inferred from homology;
KW   Nucleus {ECO:0000256|ARBA:ARBA00023242};
KW   Reference proteome {ECO:0000313|Proteomes:UP000079721}.
FT   DOMAIN          611..763
FT                   /note="RNase NYN"
FT                   /evidence="ECO:0000259|Pfam:PF11977"
FT   REGION          199..227
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          284..313
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        202..227
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        284..303
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   890 AA;  99594 MW;  80DF0BF15CED0CE8 CRC64;
     MAARAVLDEF TAPAEKAALL ERSRGRIEGL FGVSLAVLGA LGSEEPLPAR IWLQLQGKQE
     AVHSAKEYIK GICEPELEER ECYPKAMHCI FVGAQSLFLK SLIQDTCADL CILDIGLLGI
     RGSAEAVVMA RSHIQQFVKL FENNENLPSS QKESEVKREF KQFVEARADN YTMDLLILPT
     SLKKELLTLT QGEDNLFETG VDDASDTRNS GQTEFSQNAA TGLNTSSDEI VLQEDARNKA
     GTPVSELTKQ MDTILSSSED VVCVPINGQT LEGEVFSKDR VCHKRRSSDS EERHTKKQFS
     LENTEEGELL PGGKTSAENE IINLSDSFAD SENLSPDVKD TTEEMEYNIL VNFFKTMGYS
     QEIVEKVIRE FGPSTEPLLL LEEIEKENKR AQHRECLPGT MYPETNNTKN KGIYSSVHEL
     ATDSTPKKKN LTQQNVVEKF SQLPFKVESK PCTSDCKINN FRTAVEQKKE IWSSNQSYVC
     NVDLETDGLS PSVAPASPKE AVSFVSRGAS SHQPRIPIFS ENGLQQQVEP LLPNMKSACE
     NRSGYCTSPQ SKPNCPPLSP PKLLPHFFPS VTDAGPSDYI DSSVTGVQRF RDTLKVPYKL
     ELKNEPGRTD LKHIVIDGSN VAITHGLKKF FSCRGIAIAV EYFWKLGNRN ITVFVPQWRT
     RRDPNVTEQH FLTQLQELGI LSLTPARMVF GERIASHDDR FLLHLADKTG GIIVTNDNFR
     EFVTESVSWR EIITKRLLQY TFVGDIFMVP DDPLGRSGPR LEEFLQKEGF LRDMHPLLSA
     LPAMGMFDPN FRGPNTQAAN TSHQAPARIQ GTPRSHWLPP QPPFPILPNL PNLQQNLPMP
     AQRSSIETNE LREALLKIFP DSEQRLKIDQ ILVAHPYMKD LNALSAMVLD
//