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Database: UniProt
Entry: A0A1S3AEZ8_ERIEU
LinkDB: A0A1S3AEZ8_ERIEU
Original site: A0A1S3AEZ8_ERIEU 
ID   A0A1S3AEZ8_ERIEU        Unreviewed;       379 AA.
AC   A0A1S3AEZ8;
DT   12-APR-2017, integrated into UniProtKB/TrEMBL.
DT   12-APR-2017, sequence version 1.
DT   05-JUN-2019, entry version 20.
DE   SubName: Full=proto-oncogene c-Fos {ECO:0000313|RefSeq:XP_007533877.1};
GN   Name=FOS {ECO:0000313|RefSeq:XP_007533877.1};
OS   Erinaceus europaeus (Western European hedgehog).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Mammalia; Eutheria; Laurasiatheria; Eulipotyphla; Erinaceidae;
OC   Erinaceinae; Erinaceus.
OX   NCBI_TaxID=9365 {ECO:0000313|Proteomes:UP000079721, ECO:0000313|RefSeq:XP_007533877.1};
RN   [1] {ECO:0000313|RefSeq:XP_007533877.1}
RP   IDENTIFICATION.
RG   RefSeq;
RL   Submitted (FEB-2017) to UniProtKB.
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DR   RefSeq; XP_007533877.1; XM_007533815.1.
DR   STRING; 9365.XP_007533877.1; -.
DR   Ensembl; ENSEEUT00000013498; ENSEEUP00000012310; ENSEEUG00000013514.
DR   GeneID; 103123177; -.
DR   CTD; 2353; -.
DR   OMA; HRPACKM; -.
DR   OrthoDB; 1221590at2759; -.
DR   Proteomes; UP000079721; Genome assembly.
DR   GO; GO:0005654; C:nucleoplasm; IEA:Ensembl.
DR   GO; GO:0032993; C:protein-DNA complex; IEA:Ensembl.
DR   GO; GO:0035976; C:transcription factor AP-1 complex; IEA:Ensembl.
DR   GO; GO:0003700; F:DNA-binding transcription factor activity; IEA:Ensembl.
DR   GO; GO:0046982; F:protein heterodimerization activity; IEA:Ensembl.
DR   GO; GO:0070412; F:R-SMAD binding; IEA:Ensembl.
DR   GO; GO:0001102; F:RNA polymerase II activating transcription factor binding; IEA:Ensembl.
DR   GO; GO:0000979; F:RNA polymerase II core promoter sequence-specific DNA binding; IEA:Ensembl.
DR   GO; GO:0071276; P:cellular response to cadmium ion; IEA:Ensembl.
DR   GO; GO:0034614; P:cellular response to reactive oxygen species; IEA:Ensembl.
DR   GO; GO:0045944; P:positive regulation of transcription by RNA polymerase II; IEA:Ensembl.
DR   GO; GO:0060395; P:SMAD protein signal transduction; IEA:Ensembl.
DR   GO; GO:0007179; P:transforming growth factor beta receptor signaling pathway; IEA:Ensembl.
DR   InterPro; IPR000837; AP-1.
DR   InterPro; IPR004827; bZIP.
DR   InterPro; IPR029816; c-Fos/v-Fos.
DR   PANTHER; PTHR23351; PTHR23351; 1.
DR   PANTHER; PTHR23351:SF4; PTHR23351:SF4; 1.
DR   Pfam; PF00170; bZIP_1; 1.
DR   PRINTS; PR00042; LEUZIPPRFOS.
DR   SMART; SM00338; BRLZ; 1.
DR   PROSITE; PS50217; BZIP; 1.
DR   PROSITE; PS00036; BZIP_BASIC; 1.
PE   4: Predicted;
KW   Coiled coil {ECO:0000256|SAM:Coils};
KW   Complete proteome {ECO:0000313|Proteomes:UP000079721};
KW   DNA-binding {ECO:0000256|SAAS:SAAS00843640};
KW   Reference proteome {ECO:0000313|Proteomes:UP000079721}.
FT   DOMAIN      135    198       BZIP. {ECO:0000259|PROSITE:PS50217}.
FT   REGION      356    379       Disordered. {ECO:0000256|MobiDB-lite:
FT                                A0A1S3AEZ8}.
FT   COILED      133    194       {ECO:0000256|SAM:Coils}.
FT   COMPBIAS    360    379       Polar. {ECO:0000256|MobiDB-lite:
FT                                A0A1S3AEZ8}.
SQ   SEQUENCE   379 AA;  40020 MW;  232D697F0427D20B CRC64;
     MMFSGFNADY EAASSRCSSA SPAADGLAYF HSPAGSFSSL GSPVSAQDFC SDLAVSSAKF
     IPTVTAISTS PDLQWLVQPT LVSSVAPSQA RAPHPYGVPA PTAYSRSGVV KTLAGGRAQS
     IGRRGKVEQL SPEEEEKRRI RRERNKMAAA KCRNRRRELT DTLQAETDQL EDEKSALQSE
     IADLLKEKEK LEFILAAHRP ACKIPDTLGF PEEMSVVALD LPEATSPDSE DAFALPLLSD
     PEPKPSSVVE PTVKTLGGGS LGLKAEPFDD TLFPVVSRPG GLETARSVPD VDLSGSFYAA
     DWEPLHAGGS LGMGSLAAEL EPLCTPVVTC TPSCSAYTSS FVFTYPEADA FPSCAAAHRK
     GSSSEPSSDS LSSPTLLAL
//
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