ID A0A1S3AQ40_ERIEU Unreviewed; 698 AA.
AC A0A1S3AQ40;
DT 12-APR-2017, integrated into UniProtKB/TrEMBL.
DT 12-APR-2017, sequence version 1.
DT 27-MAR-2024, entry version 28.
DE SubName: Full=Transcription initiation factor TFIID subunit 4B {ECO:0000313|RefSeq:XP_007538632.1};
GN Name=LOC103127689 {ECO:0000313|RefSeq:XP_007538632.1};
OS Erinaceus europaeus (Western European hedgehog).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Laurasiatheria; Eulipotyphla; Erinaceidae; Erinaceinae;
OC Erinaceus.
OX NCBI_TaxID=9365 {ECO:0000313|Proteomes:UP000079721, ECO:0000313|RefSeq:XP_007538632.1};
RN [1] {ECO:0000313|RefSeq:XP_007538632.1}
RP IDENTIFICATION.
RG RefSeq;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
CC -!- SIMILARITY: Belongs to the TAF4 family.
CC {ECO:0000256|ARBA:ARBA00006178}.
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DR RefSeq; XP_007538632.1; XM_007538570.1.
DR AlphaFoldDB; A0A1S3AQ40; -.
DR CTD; 6875; -.
DR eggNOG; KOG2341; Eukaryota.
DR InParanoid; A0A1S3AQ40; -.
DR OrthoDB; 2910924at2759; -.
DR Proteomes; UP000079721; Unplaced.
DR GO; GO:0005669; C:transcription factor TFIID complex; IEA:InterPro.
DR GO; GO:0046982; F:protein heterodimerization activity; IEA:InterPro.
DR GO; GO:0006352; P:DNA-templated transcription initiation; IEA:InterPro.
DR GO; GO:0006366; P:transcription by RNA polymerase II; IEA:UniProt.
DR CDD; cd08045; TAF4; 1.
DR Gene3D; 1.10.20.10; Histone, subunit A; 1.
DR Gene3D; 1.20.120.1110; TAFH/NHR1 domain; 1.
DR InterPro; IPR009072; Histone-fold.
DR InterPro; IPR045144; TAF4.
DR InterPro; IPR007900; TAF4_C.
DR InterPro; IPR037249; TAFH/NHR1_dom_sf.
DR InterPro; IPR003894; TAFH_NHR1.
DR PANTHER; PTHR15138; TRANSCRIPTION INITIATION FACTOR TFIID SUBUNIT 4; 1.
DR PANTHER; PTHR15138:SF17; TRANSCRIPTION INITIATION FACTOR TFIID SUBUNIT 4B; 1.
DR Pfam; PF05236; TAF4; 1.
DR Pfam; PF07531; TAFH; 1.
DR SMART; SM00549; TAFH; 1.
DR SUPFAM; SSF47113; Histone-fold; 1.
DR SUPFAM; SSF158553; TAFH domain-like; 1.
DR PROSITE; PS51119; TAFH; 1.
PE 3: Inferred from homology;
KW Coiled coil {ECO:0000256|SAM:Coils};
KW Nucleus {ECO:0000256|ARBA:ARBA00023242};
KW Reference proteome {ECO:0000313|Proteomes:UP000079721};
KW Transcription {ECO:0000256|ARBA:ARBA00023163};
KW Transcription regulation {ECO:0000256|ARBA:ARBA00023015}.
FT DOMAIN 198..295
FT /note="TAFH"
FT /evidence="ECO:0000259|PROSITE:PS51119"
FT COILED 658..685
FT /evidence="ECO:0000256|SAM:Coils"
SQ SEQUENCE 698 AA; 73100 MW; 0BB72C81BF20430F CRC64;
MPAGLTEPAS AAPPAAPVRA LPALGPSGAP QLVAVKTPGA AAAAAIQLPA GLQLSPGTVL
IKSNTGQLML VSPQPAVTRT ETTSNATSNS TVPTHTQAVK VCTVPNSSSQ LIKKVTVAPI
KKLTQIGTTV GTTVSKPSLV QSVAVPANIV TVKPVKSLHT VAALKPSSLG VSPAVSAEPS
LNTENLAATQ AKLPPMMLEN VKKCKNFLAM LIKLACSGSQ SPEAGQNVKK LVEQLLDGKI
EAEEFTRHLY VELKSSPQPH LVSFLQKSMI ALRQLIPNPQ SFIQQCVQQT SGAVVLTTCN
TIVTPSPVVT TVSSVQPEKS MVVSGATTPR TVQSSHADPG GAKPGIVTLH PVGAAAVSGG
TAAGNVLLQT QKPLVTPAQN AVTAVSLQSE KPVISRTAVP LALPSGTFGV ASSAAICLPS
VKPIVTTAGM TSEKPVVGAP VQIRLAQPSP LVSQPAGIPQ AVRVKQLVVQ QPLGAITKQL
ATLSHSSAVT IQKAGQKVPV KTAVPTGQYS ASILKQITLP GNKILSLQAA PIQKNTENGA
TFFRDEDDFN DVTSMAGVNL NEENACILAT NSKLVGNRIH SCKDEPFLFT GALQKRILDI
GKKHGITELN SDAANLISHA TQERLRGLLE KLTTIAQHRM TTYKASENYI LSSDTRSQLK
FLEKLDHLEK QRKDLEEREM LFRAAKVRSC LLDCVNMS
//
