ID A0A1S3AQZ3_ERIEU Unreviewed; 335 AA.
AC A0A1S3AQZ3;
DT 12-APR-2017, integrated into UniProtKB/TrEMBL.
DT 12-APR-2017, sequence version 1.
DT 27-MAR-2024, entry version 26.
DE SubName: Full=GTPase IMAP family member 2-like {ECO:0000313|RefSeq:XP_007539233.1};
GN Name=LOC103128320 {ECO:0000313|RefSeq:XP_007539233.1};
OS Erinaceus europaeus (Western European hedgehog).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Laurasiatheria; Eulipotyphla; Erinaceidae; Erinaceinae;
OC Erinaceus.
OX NCBI_TaxID=9365 {ECO:0000313|Proteomes:UP000079721, ECO:0000313|RefSeq:XP_007539233.1};
RN [1] {ECO:0000313|RefSeq:XP_007539233.1}
RP IDENTIFICATION.
RG RefSeq;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SIMILARITY: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like
CC GTPase superfamily. AIG1/Toc34/Toc159-like paraseptin GTPase family.
CC IAN subfamily. {ECO:0000256|ARBA:ARBA00008535}.
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DR RefSeq; XP_007539233.1; XM_007539171.2.
DR AlphaFoldDB; A0A1S3AQZ3; -.
DR CTD; 26157; -.
DR eggNOG; ENOG502RB0C; Eukaryota.
DR InParanoid; A0A1S3AQZ3; -.
DR OrthoDB; 938643at2759; -.
DR Proteomes; UP000079721; Unplaced.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
DR CDD; cd01852; AIG1; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR InterPro; IPR006703; G_AIG1.
DR InterPro; IPR045058; GIMA/IAN/Toc.
DR InterPro; IPR027417; P-loop_NTPase.
DR PANTHER; PTHR10903:SF7; GTPASE IMAP FAMILY MEMBER 2; 1.
DR PANTHER; PTHR10903; GTPASE, IMAP FAMILY MEMBER-RELATED; 1.
DR Pfam; PF04548; AIG1; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR PROSITE; PS51720; G_AIG1; 1.
PE 3: Inferred from homology;
KW Membrane {ECO:0000256|SAM:Phobius};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Reference proteome {ECO:0000313|Proteomes:UP000079721};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 269..294
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 300..319
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 32..235
FT /note="AIG1-type G"
FT /evidence="ECO:0000259|PROSITE:PS51720"
FT REGION 1..30
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 335 AA; 36931 MW; E0A2885F829ED418 CRC64;
MPAALLPAAE QRGGSTRPMP QGQFRKTPHT RASELRIILV GKSGTGKSAT GNSILARREF
ESRLSTQSVT KTCRRSLGSW AGREVAIVDT PGVFSAQDRS ELPHTEVQRC YELSAPGPHV
LLLVAQLGRF TSQDQQAAQR VMEIFGEDAL AHTILLFTHK EDLGGGSFTD YIRHSDNRAL
SALVAACGGR VCAFNNRATG REREGQVAEL MDMIQRLVTE KGGEPYTNQL YSLVAGSKDG
PPEGFEASLS QYMETQRRRM SGASCLQRAL VQTAACVLFC LQLICKVLVL LFYILYHVCY
LLYLVFWVCA VSCRLLLVIP HRLMAALRKF HGVPN
//
