ID A0A1S3ARS6_ERIEU Unreviewed; 1715 AA.
AC A0A1S3ARS6;
DT 12-APR-2017, integrated into UniProtKB/TrEMBL.
DT 12-APR-2017, sequence version 1.
DT 27-MAR-2024, entry version 27.
DE SubName: Full=Sialoadhesin {ECO:0000313|RefSeq:XP_007539653.1};
GN Name=SIGLEC1 {ECO:0000313|RefSeq:XP_007539653.1};
OS Erinaceus europaeus (Western European hedgehog).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Laurasiatheria; Eulipotyphla; Erinaceidae; Erinaceinae;
OC Erinaceus.
OX NCBI_TaxID=9365 {ECO:0000313|Proteomes:UP000079721, ECO:0000313|RefSeq:XP_007539653.1};
RN [1] {ECO:0000313|RefSeq:XP_007539653.1}
RP IDENTIFICATION.
RG RefSeq;
RL Submitted (NOV-2023) to UniProtKB.
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DR RefSeq; XP_007539653.1; XM_007539591.2.
DR STRING; 9365.ENSEEUP00000008708; -.
DR GeneID; 103128689; -.
DR CTD; 6614; -.
DR eggNOG; KOG4475; Eukaryota.
DR InParanoid; A0A1S3ARS6; -.
DR OrthoDB; 5360480at2759; -.
DR Proteomes; UP000079721; Unplaced.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR CDD; cd00096; Ig; 3.
DR Gene3D; 2.60.40.10; Immunoglobulins; 17.
DR InterPro; IPR013162; CD80_C2-set.
DR InterPro; IPR007110; Ig-like_dom.
DR InterPro; IPR036179; Ig-like_dom_sf.
DR InterPro; IPR013783; Ig-like_fold.
DR InterPro; IPR013098; Ig_I-set.
DR InterPro; IPR003599; Ig_sub.
DR InterPro; IPR003598; Ig_sub2.
DR InterPro; IPR013106; Ig_V-set.
DR PANTHER; PTHR47243; SIALOADHESIN; 1.
DR PANTHER; PTHR47243:SF1; SIALOADHESIN; 1.
DR Pfam; PF08205; C2-set_2; 1.
DR Pfam; PF07679; I-set; 4.
DR Pfam; PF13895; Ig_2; 6.
DR Pfam; PF13927; Ig_3; 1.
DR Pfam; PF07686; V-set; 1.
DR SMART; SM00409; IG; 15.
DR SMART; SM00408; IGc2; 14.
DR SUPFAM; SSF48726; Immunoglobulin; 14.
DR PROSITE; PS50835; IG_LIKE; 13.
PE 4: Predicted;
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000079721};
KW Signal {ECO:0000256|SAM:SignalP};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT SIGNAL 1..19
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 20..1715
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5010222620"
FT TRANSMEM 1629..1652
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 238..316
FT /note="Ig-like"
FT /evidence="ECO:0000259|PROSITE:PS50835"
FT DOMAIN 317..407
FT /note="Ig-like"
FT /evidence="ECO:0000259|PROSITE:PS50835"
FT DOMAIN 415..507
FT /note="Ig-like"
FT /evidence="ECO:0000259|PROSITE:PS50835"
FT DOMAIN 508..593
FT /note="Ig-like"
FT /evidence="ECO:0000259|PROSITE:PS50835"
FT DOMAIN 697..781
FT /note="Ig-like"
FT /evidence="ECO:0000259|PROSITE:PS50835"
FT DOMAIN 789..878
FT /note="Ig-like"
FT /evidence="ECO:0000259|PROSITE:PS50835"
FT DOMAIN 888..967
FT /note="Ig-like"
FT /evidence="ECO:0000259|PROSITE:PS50835"
FT DOMAIN 974..1069
FT /note="Ig-like"
FT /evidence="ECO:0000259|PROSITE:PS50835"
FT DOMAIN 1071..1151
FT /note="Ig-like"
FT /evidence="ECO:0000259|PROSITE:PS50835"
FT DOMAIN 1158..1243
FT /note="Ig-like"
FT /evidence="ECO:0000259|PROSITE:PS50835"
FT DOMAIN 1245..1325
FT /note="Ig-like"
FT /evidence="ECO:0000259|PROSITE:PS50835"
FT DOMAIN 1430..1500
FT /note="Ig-like"
FT /evidence="ECO:0000259|PROSITE:PS50835"
FT DOMAIN 1523..1616
FT /note="Ig-like"
FT /evidence="ECO:0000259|PROSITE:PS50835"
SQ SEQUENCE 1715 AA; 184319 MW; 7734561064BAA143 CRC64;
MELLPQLLLL VSSVPLGLAN WGVSSPPTVQ GVKGSCLIIP CIFNFPDTMK VTSSITTIWY
YDYSNSRKVV IHSDEPQLVE GRFRGRAQLL GSAKNKVCNL LLKDLKPEDS GSYNFRFEIN
DVDRWSDVKG TVVTVTDLPR APTIAVPDKL IEGMEVDFNC STPYVCSQEL IRLQWQGQDP
AHFVTSNIQK LEPTGISHME TFHSTLSWQD HGRILRCQLS VGTHKTEGEI HLQVQYAPKG
VAVLLSPSGR NILAGDLVTL TCQVNSSYPE INSVQWEKDG ESLKAQGRVL QLPKAAWEDA
GVYTCQAGNS VGSSISPPVS LHVFMVEIQM SPAGPVLENQ TVTLTCNTPR EAAKQLHYSW
YKNQALLGGA HSSTLRLRSV TRADSGFYYC VVENIQGSQR SDAVSVEVRH PPLVPDLTAL
LDMQAGLVGI IHCSVVSEPL ATLVLSHRGH ILASTSWGSD QSPRFSVSFA PNNLRLEIRE
LRPSDSGEYM CSAANVLGNS SSSLDFHTNV ARVLISPAAD VVEGQAVTLS CKSGLSPTPD
ARFTWYRNGA LLLEGPRSSL LLPAATSADA GSYHCRVQDH LISSGPSSPA ILSVLYAPRQ
PTFTAGPDPD AGQQGLLLCR VDSDPPAQLR LLHGDHVVAT SLPTCGGCSQ RAKVTRAPNF
LRVQIRSPVL EDEGVYVCEA SNALGNASAL ATFHAQATVL VVTPSNKVPE GSVVNLTCNV
SRESSGGPSN FSWFRNGVQW AQGPLETITL LPVARTDAAL YACCIHTEAG AAELSTPVVL
TVLYPPDPPK LSALLDVDQG HVAMFFCSVD SSPLAQLTLF HEQHLLASSP RLQLPSHDRL
QVKAMANSLQ LKIQDLGLGD SGNYHCEATN ELGSANTSLF FQVRGAWVQV SPSPELREGQ
AVVLKCRVPV GIPEETSYQW YWNGQPLEDS TSATLHFAAI TLSQAGAYHC QSQAPGSATL
NLAAPVSLHI SYAPRQVTLT ALMDTGPGRL GLLLCCVRSD PPAQLRLLHG AQMVASTLQG
VGSSARLQLA VAPNTLRLEI HNATLEDEGV YTCQAINTLG QASASANFDA QAVSVQVWPN
TTVHEGQLVN LTCLVWTSQL AQLIYTWYQD GQRRPSAHSI LLPNVTVMDA ATYRCSVASP
GQAPHLSRPV TLDVLYAPRS LRLISLLEQQ GGRRALLLCT VDSRPPAQLT LSRNGHLLAS
STAASVPNTL NLELREPQPS DEGHYSCSAQ NPLGQADMSL ELQLEGVQVT LTPSAAVPEG
TPVTVTCEDP AARPPVLYAW YHNARWLQEG LAASLSFPKA TQAHAGTYTC QVQDAQGTRS
SRPVALQILY APRNAILSSF LDSRTSPMAV VQCTVDSEPP AELALSLDGK VLATSRKAHG
LAWGIGHVQV ARNALRLQVQ DVSSGGEDTY VCTAHNLLGS VSTTAQLQTE GVHVVAEPGL
DLPEGAALNL SCHLPGVLGP MTNSTFIWFW NGRQLHTEPA PTLSFTPVGR TNAGLYHCRA
VLPFGTTTSA PVMLHVLYPP GTPAITVFVE PEDGSQGILD CRVDSEPLAS LALHLGSRLV
ASSQPMAASA ESHIRVSATP NVLRVDIQEL RPSDQGEYTC SASNALGSAS ASAYFGTRAV
YRLHLFQQLL WVLGLLAGIL FLLLGLGATW AWRRRFFHMP RAGENLVEMT SQKETTKEQE
VAGICNTLVL ENEAVLGPAG LCENNDNSGV RADFL
//
