ID A0A1S3AUX3_CUCME Unreviewed; 512 AA.
AC A0A1S3AUX3;
DT 12-APR-2017, integrated into UniProtKB/TrEMBL.
DT 12-APR-2017, sequence version 1.
DT 27-MAR-2024, entry version 27.
DE SubName: Full=Protein VASCULAR ASSOCIATED DEATH 1, chloroplastic isoform X6 {ECO:0000313|RefSeq:XP_008437769.1};
GN Name=LOC103483102 {ECO:0000313|RefSeq:XP_008437769.1};
OS Cucumis melo (Muskmelon).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; fabids; Cucurbitales; Cucurbitaceae; Benincaseae; Cucumis.
OX NCBI_TaxID=3656 {ECO:0000313|Proteomes:UP000089565, ECO:0000313|RefSeq:XP_008437769.1};
RN [1] {ECO:0000313|Proteomes:UP000089565}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. DHL92 {ECO:0000313|Proteomes:UP000089565};
RX PubMed=22753475; DOI=10.1073/pnas.1205415109;
RA Garcia-Mas J., Benjak A., Sanseverino W., Bourgeois M., Mir G.,
RA Gonzalez V.M., Henaff E., Camara F., Cozzuto L., Lowy E., Alioto T.,
RA Capella-Gutierrez S., Blanca J., Canizares J., Ziarsolo P.,
RA Gonzalez-Ibeas D., Rodriguez-Moreno L., Droege M., Du L.,
RA Alvarez-Tejado M., Lorente-Galdos B., Mele M., Yang L., Weng Y.,
RA Navarro A., Marques-Bonet T., Aranda M.A., Nuez F., Pico B., Gabaldon T.,
RA Roma G., Guigo R., Casacuberta J.M., Arus P., Puigdomenech P.;
RT "The genome of melon (Cucumis melo L.).";
RL Proc. Natl. Acad. Sci. U.S.A. 109:11872-11877(2012).
RN [2] {ECO:0000313|RefSeq:XP_008437769.1}
RP IDENTIFICATION.
RG RefSeq;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004167}; Single-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004167}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR RefSeq; XP_008437769.1; XM_008439547.2.
DR AlphaFoldDB; A0A1S3AUX3; -.
DR GeneID; 103483102; -.
DR OrthoDB; 45896at2759; -.
DR Proteomes; UP000089565; Unplaced.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0042742; P:defense response to bacterium; IEA:EnsemblPlants.
DR GO; GO:0043069; P:negative regulation of programmed cell death; IEA:EnsemblPlants.
DR GO; GO:0009723; P:response to ethylene; IEA:EnsemblPlants.
DR GO; GO:0009751; P:response to salicylic acid; IEA:EnsemblPlants.
DR CDD; cd13220; PH-GRAM_GRAMDC; 1.
DR Gene3D; 2.30.29.30; Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB); 1.
DR InterPro; IPR004182; GRAM.
DR InterPro; IPR011993; PH-like_dom_sf.
DR InterPro; IPR031968; VASt.
DR PANTHER; PTHR47666; PROTEIN VASCULAR ASSOCIATED DEATH 1, CHLOROPLASTIC; 1.
DR PANTHER; PTHR47666:SF1; TBC1 DOMAIN FAMILY MEMBER 9B ISOFORM X1; 1.
DR Pfam; PF02893; GRAM; 1.
DR Pfam; PF16016; VASt; 1.
DR SMART; SM00568; GRAM; 1.
DR PROSITE; PS51778; VAST; 1.
PE 4: Predicted;
KW Membrane {ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000089565};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 495..511
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 232..409
FT /note="VASt"
FT /evidence="ECO:0000259|PROSITE:PS51778"
FT REGION 1..60
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 411..467
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 25..49
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 424..448
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 449..467
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 512 AA; 58630 MW; CCF51DC19F80DAB2 CRC64;
MAAAASAAAP EIIELPRPRD KLPTNLSPDS ASCYPPESSS SSADRISDTH ESSSSPDGFH
EDVEIQSSAL LRSEEYRQLF RLPLDEVLIE DFNCAFQENI LIQGHMYLFV HYICFYSNIF
GFETKKIIPF REIIAVRKAK TAGIFPNAIE ICDGEKKYFF ASFLSRDEAF NLINDGWLQH
AKGTEATMTK QKSINESSRQ EIGILGVEKA KELDPSDSSD STRLLYPSCR IKVSEKLVQL
EWQINVEDFF SFYFSDNAVD FVSSYHEKCG DKELKCSLWR HDDMFGHMRD VSFQHPIKIY
FGAKFGGCRE TQKFRVYRDR FENHLVIEVT QEVSEVPYSD YFRVEAHWEV KKDVDDKSNN
GCILRVYVNV AFSKRTVWKG KIVQSTLEEC REAYGLWIQM AKELLKQKLT GSEEGTSGST
SQSGKDHHIE KERNNNKSLE KSNEKNDQRR STASQYSTDV DQQAKNSIQG VNSTSAASWL
REYIKKLWIV LRSQNYLPLA LVITFAVIFL CS
//
