ID   A0A1S3B0K9_CUCME        Unreviewed;       967 AA.
AC   A0A1S3B0K9;
DT   12-APR-2017, integrated into UniProtKB/TrEMBL.
DT   12-APR-2017, sequence version 1.
DT   27-MAR-2024, entry version 33.
DE   SubName: Full=Extra-large guanine nucleotide-binding protein 1 isoform X1 {ECO:0000313|RefSeq:XP_008440199.1, ECO:0000313|RefSeq:XP_008440201.1};
GN   Name=LOC103484734 {ECO:0000313|RefSeq:XP_008440199.1,
GN   ECO:0000313|RefSeq:XP_008440201.1};
OS   Cucumis melo (Muskmelon).
OC   Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC   Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC   rosids; fabids; Cucurbitales; Cucurbitaceae; Benincaseae; Cucumis.
OX   NCBI_TaxID=3656 {ECO:0000313|Proteomes:UP000089565, ECO:0000313|RefSeq:XP_008440199.1};
RN   [1] {ECO:0000313|Proteomes:UP000089565}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=cv. DHL92 {ECO:0000313|Proteomes:UP000089565};
RX   PubMed=22753475; DOI=10.1073/pnas.1205415109;
RA   Garcia-Mas J., Benjak A., Sanseverino W., Bourgeois M., Mir G.,
RA   Gonzalez V.M., Henaff E., Camara F., Cozzuto L., Lowy E., Alioto T.,
RA   Capella-Gutierrez S., Blanca J., Canizares J., Ziarsolo P.,
RA   Gonzalez-Ibeas D., Rodriguez-Moreno L., Droege M., Du L.,
RA   Alvarez-Tejado M., Lorente-Galdos B., Mele M., Yang L., Weng Y.,
RA   Navarro A., Marques-Bonet T., Aranda M.A., Nuez F., Pico B., Gabaldon T.,
RA   Roma G., Guigo R., Casacuberta J.M., Arus P., Puigdomenech P.;
RT   "The genome of melon (Cucumis melo L.).";
RL   Proc. Natl. Acad. Sci. U.S.A. 109:11872-11877(2012).
RN   [2] {ECO:0000313|RefSeq:XP_008440199.1, ECO:0000313|RefSeq:XP_008440201.1}
RP   IDENTIFICATION.
RG   RefSeq;
RL   Submitted (NOV-2023) to UniProtKB.
CC   -!- SIMILARITY: Belongs to the G-alpha family.
CC       {ECO:0000256|ARBA:ARBA00005804}.
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DR   RefSeq; XP_008440199.1; XM_008441977.1.
DR   RefSeq; XP_008440201.1; XM_008441979.2.
DR   GeneID; 103484734; -.
DR   KEGG; cmo:103484734; -.
DR   eggNOG; KOG0082; Eukaryota.
DR   OrthoDB; 1221906at2759; -.
DR   Proteomes; UP000089565; Unplaced.
DR   GO; GO:0031683; F:G-protein beta/gamma-subunit complex binding; IEA:InterPro.
DR   GO; GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
DR   GO; GO:0003924; F:GTPase activity; IEA:InterPro.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0007186; P:G protein-coupled receptor signaling pathway; IEA:InterPro.
DR   CDD; cd00066; G-alpha; 1.
DR   Gene3D; 1.10.400.10; GI Alpha 1, domain 2-like; 1.
DR   Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR   InterPro; IPR001019; Gprotein_alpha_su.
DR   InterPro; IPR011025; GproteinA_insert.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   InterPro; IPR011011; Znf_FYVE_PHD.
DR   PANTHER; PTHR36486; OS01G0977800 PROTEIN; 1.
DR   PANTHER; PTHR36486:SF4; PH DOMAIN-CONTAINING PROTEIN; 1.
DR   Pfam; PF00503; G-alpha; 1.
DR   PRINTS; PR00318; GPROTEINA.
DR   SMART; SM00275; G_alpha; 1.
DR   SUPFAM; SSF57903; FYVE/PHD zinc finger; 1.
DR   SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR   SUPFAM; SSF47895; Transducin (alpha subunit), insertion domain; 1.
DR   PROSITE; PS51882; G_ALPHA; 1.
PE   3: Inferred from homology;
KW   GTP-binding {ECO:0000256|ARBA:ARBA00023134};
KW   Lipoprotein {ECO:0000256|ARBA:ARBA00022707};
KW   Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW   Myristate {ECO:0000256|ARBA:ARBA00022707};
KW   Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW   Reference proteome {ECO:0000313|Proteomes:UP000089565};
KW   Transducer {ECO:0000256|ARBA:ARBA00023224};
KW   Zinc {ECO:0000256|ARBA:ARBA00022833};
KW   Zinc-finger {ECO:0000256|ARBA:ARBA00022771}.
SQ   SEQUENCE   967 AA;  107473 MW;  4547D114BAE77603 CRC64;
     MPLVEAMVAD PVDGIQYSFA KEYKGPPVPY DLPQALPINV ERIPVAAVVA EVPFTHKMSL
     PVVQPILAQD VMSKKFSKEL EPAVGKSVVS PTSVIAFDQS TEDSRRCLSK ESDSGSERTV
     SPTSVIAFED RVVGNHGCQL SGDLSSSGAL EFSNGQIVSG ELSDVGNCSR AFACSSISHG
     NSCELLGDAG SSCTMEFSGS FNKSQRSSCS LRASNCRKES IDFNDIHQVD WVSTESVLSS
     DYPSSRVSSM KVVNEGGGDG RRSAVTFLDP ESDYTYNEEY SQDGPETLRM RQDSLRKGKK
     GSCYRCGKGN RFTEKEVCIV CDAKYCSNCV LRAMGSMPEG RKCVTCIGFP IDESKRGNLG
     KCPRMLKRLL NDLEIRQVMT AEKCCEANQL PPEYVCVNGE PLSFEELSML QTCPNPPKKL
     KPGNYWYDKV SGLWGKEGQK PSKIITPHLN IGGPIKADAS NGNTKIFING REITKVELRM
     LQLAGVQCAG NPHFWVNEDG SYQEEGQKNT KGYIWGKAGT KLVCALLSLP VPSKSSNYSG
     EPDSSLVYRT FPEYLGLQKL LLVGYDGSGT STIFKQAKIL YKDAPFSKEE REIIKLKIQS
     NVYGYLGIIL EGRERFEEDS SAEIRKKLSD EVDPAAGSSS VDSDKSMYSI GPRLKAFSDW
     LLKTMVSGTL ETIFPAATRE YAPLVEELWN DAAIQATYKR GSELEMLPNV AHYFLERVVD
     ILTTDYEPSD SDILYAEGLI SSNGLACVDF SFPQPAPDDD IDTADQHSSL LRYQLIRAHA
     RGIGENCKWL EMFEDIGIVI FCVSLSDYDQ FSIDGNGDTV NKMLLSRKFF ESLVTHPTFY
     QMDFLVLLNK YDQFEEKVER VPLTRCEWFN DFHPMISRNR SNSQNNINSS PSLGQLGFHY
     IAVKFKRLFT SLTGRKLYVS PVKGLEPHSV DAALKYAREI MKWDEERTNF SLSEYSVYST
     EESSFSH
//