ID A0A1S3BFN4_CUCME Unreviewed; 714 AA.
AC A0A1S3BFN4;
DT 12-APR-2017, integrated into UniProtKB/TrEMBL.
DT 12-APR-2017, sequence version 1.
DT 27-MAR-2024, entry version 29.
DE SubName: Full=CSC1-like protein At1g69450 {ECO:0000313|RefSeq:XP_008446400.1};
GN Name=LOC103489156 {ECO:0000313|RefSeq:XP_008446400.1};
GN Synonyms=103489156 {ECO:0000313|EnsemblPlants:MELO3C012126.2.1};
OS Cucumis melo (Muskmelon).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; fabids; Cucurbitales; Cucurbitaceae; Benincaseae; Cucumis.
OX NCBI_TaxID=3656 {ECO:0000313|Proteomes:UP000089565, ECO:0000313|RefSeq:XP_008446400.1};
RN [1] {ECO:0000313|Proteomes:UP000089565}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. DHL92 {ECO:0000313|Proteomes:UP000089565};
RX PubMed=22753475; DOI=10.1073/pnas.1205415109;
RA Garcia-Mas J., Benjak A., Sanseverino W., Bourgeois M., Mir G.,
RA Gonzalez V.M., Henaff E., Camara F., Cozzuto L., Lowy E., Alioto T.,
RA Capella-Gutierrez S., Blanca J., Canizares J., Ziarsolo P.,
RA Gonzalez-Ibeas D., Rodriguez-Moreno L., Droege M., Du L.,
RA Alvarez-Tejado M., Lorente-Galdos B., Mele M., Yang L., Weng Y.,
RA Navarro A., Marques-Bonet T., Aranda M.A., Nuez F., Pico B., Gabaldon T.,
RA Roma G., Guigo R., Casacuberta J.M., Arus P., Puigdomenech P.;
RT "The genome of melon (Cucumis melo L.).";
RL Proc. Natl. Acad. Sci. U.S.A. 109:11872-11877(2012).
RN [2] {ECO:0000313|EnsemblPlants:MELO3C012126.2.1}
RP IDENTIFICATION.
RG EnsemblPlants;
RL Submitted (MAR-2023) to UniProtKB.
RN [3] {ECO:0000313|RefSeq:XP_008446400.1}
RP IDENTIFICATION.
RG RefSeq;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the CSC1 (TC 1.A.17) family.
CC {ECO:0000256|ARBA:ARBA00007779}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR RefSeq; XP_008446400.1; XM_008448178.2.
DR EnsemblPlants; MELO3C012126.2.1; MELO3C012126.2.1; MELO3C012126.2.
DR GeneID; 103489156; -.
DR Gramene; MELO3C012126.2.1; MELO3C012126.2.1; MELO3C012126.2.
DR KEGG; cmo:103489156; -.
DR eggNOG; KOG1134; Eukaryota.
DR InParanoid; A0A1S3BFN4; -.
DR OrthoDB; 1753647at2759; -.
DR Proteomes; UP000089565; Unplaced.
DR Proteomes; UP000596662; Unplaced.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0005227; F:calcium-activated cation channel activity; IEA:InterPro.
DR InterPro; IPR045122; Csc1-like.
DR InterPro; IPR003864; CSC1/OSCA1-like_7TM.
DR InterPro; IPR027815; CSC1/OSCA1-like_cyt.
DR InterPro; IPR032880; Csc1/OSCA1-like_N.
DR PANTHER; PTHR13018; PROBABLE MEMBRANE PROTEIN DUF221-RELATED; 1.
DR PANTHER; PTHR13018:SF104; RSN1_7TM DOMAIN-CONTAINING PROTEIN; 1.
DR Pfam; PF14703; PHM7_cyt; 1.
DR Pfam; PF02714; RSN1_7TM; 1.
DR Pfam; PF13967; RSN1_TM; 1.
PE 3: Inferred from homology;
KW Calcium {ECO:0000256|ARBA:ARBA00022837};
KW Ion channel {ECO:0000256|ARBA:ARBA00023303};
KW Ion transport {ECO:0000256|ARBA:ARBA00023303};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000089565};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}; Transport {ECO:0000256|ARBA:ARBA00022448}.
FT TRANSMEM 6..27
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 86..110
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 146..167
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 359..378
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 390..412
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 451..470
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 550..582
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 603..624
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 630..649
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 5..168
FT /note="CSC1/OSCA1-like N-terminal transmembrane"
FT /evidence="ECO:0000259|Pfam:PF13967"
FT DOMAIN 189..345
FT /note="CSC1/OSCA1-like cytosolic"
FT /evidence="ECO:0000259|Pfam:PF14703"
FT DOMAIN 358..623
FT /note="CSC1/OSCA1-like 7TM region"
FT /evidence="ECO:0000259|Pfam:PF02714"
SQ SEQUENCE 714 AA; 80878 MW; BA7660FD62DD8091 CRC64;
MFVSALLTSV GINSAICFSF LVLYSILRKQ PAYYSIYIPR LVAEGKTKQR SDFNLERLIP
SANWLKKAWM LSEEELLSSS GLDAVVFMRI VTFSLKVLLF AGVIGIFVLL PVNCSGDQLA
DVDIANISNN SLDVFTISNV KDGSHWLWIH FSAVYLITAY ICCLLYYEYD YISSKRIEYF
CSSKPLFHQF TILVRGIPAS PGRNISDTVE NFFTEYHPST YLSHTVVRRT SKLRGLIHDA
KTYYRKLVRL QSNPAQVNSN RGSCFGLFRR KADLVDRYGK RLGDIEQHLR LEQSEVSSAG
KEVPAAFVSF KSRYGAAISM HMQQSNNPIQ WVTEQAPEPH DVYWPFFSST FMQRWLSKLG
VAVACFLLIV LFFIPVVLVQ GLTNLNQLQI WFPFLKSILT ITFISQVITG YLPSLILQMF
MKMVPPIMEC LSSIQGYISL SDIKKSACFK VLWFTIWNVF FATVFSGTAL SQLSLVFEPK
NIPTKLAVAV PGQASFFIAY VVTSGWTSSL SELINLFPLI TSLVTRPFSG NSDDELEVPS
IPYHKDIPNI LFFVLLGITY FFLAPLILPF LFVYFSLEYI VYRNQFLNVY APKYETAGKF
WPIAHSCMIF SLLLMHAIAV GIFTLKGLPL ASTLVVPLPI LTLLFNEYCR KRFLPNFSAY
SAEALITKDR EDQNDPAMAE FFDKLVTAYG DPALMPVSFT TNADSLNRPL MSED
//
