ID A0A1S3C353_CUCME Unreviewed; 723 AA.
AC A0A1S3C353;
DT 12-APR-2017, integrated into UniProtKB/TrEMBL.
DT 12-APR-2017, sequence version 1.
DT 27-MAR-2024, entry version 33.
DE SubName: Full=Homeobox-leucine zipper protein HDG2-like isoform X2 {ECO:0000313|RefSeq:XP_008455853.1};
GN Name=LOC103495949 {ECO:0000313|RefSeq:XP_008455853.1};
OS Cucumis melo (Muskmelon).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; fabids; Cucurbitales; Cucurbitaceae; Benincaseae; Cucumis.
OX NCBI_TaxID=3656 {ECO:0000313|Proteomes:UP000089565, ECO:0000313|RefSeq:XP_008455853.1};
RN [1] {ECO:0000313|Proteomes:UP000089565}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. DHL92 {ECO:0000313|Proteomes:UP000089565};
RX PubMed=22753475; DOI=10.1073/pnas.1205415109;
RA Garcia-Mas J., Benjak A., Sanseverino W., Bourgeois M., Mir G.,
RA Gonzalez V.M., Henaff E., Camara F., Cozzuto L., Lowy E., Alioto T.,
RA Capella-Gutierrez S., Blanca J., Canizares J., Ziarsolo P.,
RA Gonzalez-Ibeas D., Rodriguez-Moreno L., Droege M., Du L.,
RA Alvarez-Tejado M., Lorente-Galdos B., Mele M., Yang L., Weng Y.,
RA Navarro A., Marques-Bonet T., Aranda M.A., Nuez F., Pico B., Gabaldon T.,
RA Roma G., Guigo R., Casacuberta J.M., Arus P., Puigdomenech P.;
RT "The genome of melon (Cucumis melo L.).";
RL Proc. Natl. Acad. Sci. U.S.A. 109:11872-11877(2012).
RN [2] {ECO:0000313|RefSeq:XP_008455853.1}
RP IDENTIFICATION.
RG RefSeq;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|ARBA:ARBA00004123,
CC ECO:0000256|PROSITE-ProRule:PRU00108, ECO:0000256|RuleBase:RU000682}.
CC -!- SIMILARITY: Belongs to the HD-ZIP homeobox family. Class IV subfamily.
CC {ECO:0000256|ARBA:ARBA00006789}.
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DR RefSeq; XP_008455853.1; XM_008457631.2.
DR AlphaFoldDB; A0A1S3C353; -.
DR GeneID; 103495949; -.
DR OrthoDB; 3036383at2759; -.
DR Proteomes; UP000089565; Unplaced.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-UniRule.
DR GO; GO:0000981; F:DNA-binding transcription factor activity, RNA polymerase II-specific; IEA:InterPro.
DR GO; GO:0008289; F:lipid binding; IEA:InterPro.
DR CDD; cd00086; homeodomain; 1.
DR CDD; cd08875; START_ArGLABRA2_like; 1.
DR Gene3D; 3.30.530.20; -; 1.
DR Gene3D; 1.10.10.60; Homeodomain-like; 1.
DR InterPro; IPR042160; GLABRA2/ANL2/PDF2/ATML1-like.
DR InterPro; IPR009057; Homeobox-like_sf.
DR InterPro; IPR017970; Homeobox_CS.
DR InterPro; IPR001356; Homeobox_dom.
DR InterPro; IPR023393; START-like_dom_sf.
DR InterPro; IPR002913; START_lipid-bd_dom.
DR PANTHER; PTHR45654:SF93; HOMEOBOX-LEUCINE ZIPPER PROTEIN HDG2-RELATED; 1.
DR PANTHER; PTHR45654; HOMEOBOX-LEUCINE ZIPPER PROTEIN MERISTEM L1; 1.
DR Pfam; PF00046; Homeodomain; 1.
DR Pfam; PF01852; START; 1.
DR SMART; SM00389; HOX; 1.
DR SMART; SM00234; START; 1.
DR SUPFAM; SSF55961; Bet v1-like; 2.
DR SUPFAM; SSF46689; Homeodomain-like; 1.
DR PROSITE; PS00027; HOMEOBOX_1; 1.
DR PROSITE; PS50071; HOMEOBOX_2; 1.
DR PROSITE; PS50848; START; 1.
PE 3: Inferred from homology;
KW Coiled coil {ECO:0000256|ARBA:ARBA00023054, ECO:0000256|SAM:Coils};
KW DNA-binding {ECO:0000256|ARBA:ARBA00023125, ECO:0000256|PROSITE-
KW ProRule:PRU00108};
KW Homeobox {ECO:0000256|ARBA:ARBA00023155, ECO:0000256|PROSITE-
KW ProRule:PRU00108};
KW Nucleus {ECO:0000256|ARBA:ARBA00023242, ECO:0000256|PROSITE-
KW ProRule:PRU00108}; Reference proteome {ECO:0000313|Proteomes:UP000089565}.
FT DOMAIN 56..116
FT /note="Homeobox"
FT /evidence="ECO:0000259|PROSITE:PS50071"
FT DOMAIN 241..473
FT /note="START"
FT /evidence="ECO:0000259|PROSITE:PS50848"
FT DNA_BIND 58..117
FT /note="Homeobox"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00108"
FT REGION 32..67
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 110..142
FT /evidence="ECO:0000256|SAM:Coils"
FT COMPBIAS 32..58
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 723 AA; 79508 MW; 97359E30575B715B CRC64;
MFQPSIMDAH LLPLDIPQNT SESDLARIRD DDFDSATKSG SDNNHELVSG DDQDPRPKKK
RYHRHTQHQI QEMEAFFKEC PHPDDKQRKE LSRELGLEPL QVKFWFQNKR TQMKNQHERH
ENTQLRTENE KLRADNMRYR EALSNASCPN CGGPTAIGEM SFDEHHLRLE NARLREEIDR
ISAIAAKYVG KPVVNYPLLS PPVPSRPLEL GMANFGPQPG LGGGDIYGSA SDLIRSISAP
TEADKPMIIE LAVAAMEELT RMAQMGEPLW MTTLDGSTHM LNEDEYLRTF PRGIGPKPSG
FKCEASRESA VVIMNHINLV EILMDVNQWS TLFSGIVSRA MTLEVLSTGV AGNYNGALQV
MTSEFQVPSP LVPTRESYFV RYCKQHGDGT WAVVDVSLDD LRPTPGVRCR RRPSGCLIQE
MPNGYSKVTW VEHVEVDDRG VHNLYKQLVS SGQAFGAKRW VTTLDRQCER LASAMATNIP
TGDVGVITNQ EGRKSMLKLA ERMVISFCAG VSASTTHTWT TLSGTGADDV RVMTRKSIDD
PGRPHGIVLS AATSFWLPVP PKRIFDFLRD ENSRSEWDIL SNGGVVQEMA HIANGRDTGN
CVSLLRVNSA NSSQSNMLIL QESCTDPTAS FVIYAPVDVV AMNLVLNGGD PDYVALLPSG
FAILPDGGGG EGVSGGSLLT VAFQILVDSV PTAKLSLGSV ATVNNLIACT VERIKASLSC
ENA
//
