ID A0A1S3C5G5_CUCME Unreviewed; 747 AA.
AC A0A1S3C5G5;
DT 12-APR-2017, integrated into UniProtKB/TrEMBL.
DT 12-APR-2017, sequence version 1.
DT 27-MAR-2024, entry version 31.
DE RecName: Full=non-specific serine/threonine protein kinase {ECO:0000256|ARBA:ARBA00012513};
DE EC=2.7.11.1 {ECO:0000256|ARBA:ARBA00012513};
GN Name=LOC103497076 {ECO:0000313|RefSeq:XP_008457367.1};
GN Synonyms=103497076 {ECO:0000313|EnsemblPlants:MELO3C020544.2.1};
OS Cucumis melo (Muskmelon).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; fabids; Cucurbitales; Cucurbitaceae; Benincaseae; Cucumis.
OX NCBI_TaxID=3656 {ECO:0000313|Proteomes:UP000089565, ECO:0000313|RefSeq:XP_008457367.1};
RN [1] {ECO:0000313|Proteomes:UP000089565}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. DHL92 {ECO:0000313|Proteomes:UP000089565};
RX PubMed=22753475; DOI=10.1073/pnas.1205415109;
RA Garcia-Mas J., Benjak A., Sanseverino W., Bourgeois M., Mir G.,
RA Gonzalez V.M., Henaff E., Camara F., Cozzuto L., Lowy E., Alioto T.,
RA Capella-Gutierrez S., Blanca J., Canizares J., Ziarsolo P.,
RA Gonzalez-Ibeas D., Rodriguez-Moreno L., Droege M., Du L.,
RA Alvarez-Tejado M., Lorente-Galdos B., Mele M., Yang L., Weng Y.,
RA Navarro A., Marques-Bonet T., Aranda M.A., Nuez F., Pico B., Gabaldon T.,
RA Roma G., Guigo R., Casacuberta J.M., Arus P., Puigdomenech P.;
RT "The genome of melon (Cucumis melo L.).";
RL Proc. Natl. Acad. Sci. U.S.A. 109:11872-11877(2012).
RN [2] {ECO:0000313|EnsemblPlants:MELO3C020544.2.1}
RP IDENTIFICATION.
RG EnsemblPlants;
RL Submitted (MAR-2023) to UniProtKB.
RN [3] {ECO:0000313|RefSeq:XP_008457367.1}
RP IDENTIFICATION.
RG RefSeq;
RL Submitted (NOV-2023) to UniProtKB.
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DR RefSeq; XP_008457367.1; XM_008459145.2.
DR EnsemblPlants; MELO3C020544.2.1; MELO3C020544.2.1; MELO3C020544.2.
DR GeneID; 103497076; -.
DR Gramene; MELO3C020544.2.1; MELO3C020544.2.1; MELO3C020544.2.
DR KEGG; cmo:103497076; -.
DR eggNOG; KOG1187; Eukaryota.
DR InParanoid; A0A1S3C5G5; -.
DR OrthoDB; 404991at2759; -.
DR Proteomes; UP000089565; Unplaced.
DR Proteomes; UP000596662; Unplaced.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-UniRule.
DR GO; GO:0042803; F:protein homodimerization activity; IEA:UniProt.
DR GO; GO:0004674; F:protein serine/threonine kinase activity; IEA:InterPro.
DR GO; GO:0016310; P:phosphorylation; IEA:UniProtKB-KW.
DR CDD; cd14066; STKc_IRAK; 1.
DR Gene3D; 2.130.10.30; Regulator of chromosome condensation 1/beta-lactamase-inhibitor protein II; 1.
DR Gene3D; 1.10.510.10; Transferase(Phosphotransferase) domain 1; 1.
DR InterPro; IPR044815; CCR1-4.
DR InterPro; IPR011009; Kinase-like_dom_sf.
DR InterPro; IPR000719; Prot_kinase_dom.
DR InterPro; IPR017441; Protein_kinase_ATP_BS.
DR InterPro; IPR009091; RCC1/BLIP-II.
DR InterPro; IPR008271; Ser/Thr_kinase_AS.
DR PANTHER; PTHR46146:SF1; PROTEIN KINASE DOMAIN-CONTAINING PROTEIN; 1.
DR PANTHER; PTHR46146; SERINE/THREONINE-PROTEIN KINASE-LIKE PROTEIN CCR4; 1.
DR Pfam; PF00069; Pkinase; 1.
DR Pfam; PF13540; RCC1_2; 1.
DR SMART; SM00220; S_TKc; 1.
DR SUPFAM; SSF56112; Protein kinase-like (PK-like); 1.
DR SUPFAM; SSF50985; RCC1/BLIP-II; 1.
DR PROSITE; PS00107; PROTEIN_KINASE_ATP; 1.
DR PROSITE; PS50011; PROTEIN_KINASE_DOM; 1.
DR PROSITE; PS00108; PROTEIN_KINASE_ST; 1.
PE 4: Predicted;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840, ECO:0000256|PROSITE-
KW ProRule:PRU10141};
KW Kinase {ECO:0000256|ARBA:ARBA00022777, ECO:0000313|RefSeq:XP_008457367.1};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741, ECO:0000256|PROSITE-
KW ProRule:PRU10141}; Reference proteome {ECO:0000313|Proteomes:UP000089565};
KW Signal {ECO:0000256|SAM:SignalP};
KW Transferase {ECO:0000256|ARBA:ARBA00022679}.
FT SIGNAL 1..23
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 24..747
FT /note="non-specific serine/threonine protein kinase"
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5041162553"
FT DOMAIN 453..736
FT /note="Protein kinase"
FT /evidence="ECO:0000259|PROSITE:PS50011"
FT BINDING 481
FT /ligand="ATP"
FT /ligand_id="ChEBI:CHEBI:30616"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU10141"
SQ SEQUENCE 747 AA; 80365 MW; EBBB99BE31A1BF35 CRC64;
MTSELVILVV VLITLQLHWA VDALGSASTV AVAYGTSTVC GISAGKKSQR IQCYRGDQVI
SILPQVSFQA ISGGQSFFCG LRTGGFSLHC WETDAGFSNR SFQPKRIYYS INFPLTDLAV
GDAQVCAREV SSGKVICWRG SNRVGSLFPS PDPALNFQTI TSGSGFSCGI LKNKTVWCWG
NNGIGSKIQS QFGNLPMASL VAGESHVCGL TALGGVLVCK GNNNGGQLEV PSNSAHEYSN
LALGTSFTCA IRQDNGVVSC WGEGANKLNI EKNINVSVSY ELITAGSYML CGLKTNNLTI
MCWSKANNKS PVLLPLGMII PGPCVQDSCS RCGIYPNSAF LCDGSGNICK SCQRELPFAV
PLPTSPNSSS NPASSSPTKA RNRLTTALLI VGAIGALAGT FTILFCISNC LTSRSSCNTA
NNQEQNINQL SLIEHSSARA FSLMELAVAT NNFSSENKIG AGSFGVVYKG KLTDGTEVAI
KRGETKNDEK TEDPQEKQNA FCSELTTVLR LNHKHLVGMV GYCQENDERL LVYEYMTNGS
LHDHLHNKDG VLLNTWNIRI KIALDAARGI EYLHNYAVPP IIHRDIKSSN ILLDGNFTAR
VSDFGLSLMR QPETSMESAV GGTIGYIDPE YYVSKISTAK SDVYGLGVVL LELLTGKKAV
FRDSEGGGPV TVAEYAVERI GRGELWNVVD KRVRGAEMKE VDAVEMVAYT AMHCVKLEGE
ERPNIGDIVE NLEKAVGLCN GELRDSF
//
