ID A0A1S3C724_CUCME Unreviewed; 2222 AA.
AC A0A1S3C724;
DT 12-APR-2017, integrated into UniProtKB/TrEMBL.
DT 12-APR-2017, sequence version 1.
DT 27-MAR-2024, entry version 33.
DE SubName: Full=Phragmoplast orienting kinesin-1 isoform X1 {ECO:0000313|RefSeq:XP_008458297.1};
GN Name=LOC103497757 {ECO:0000313|RefSeq:XP_008458297.1};
OS Cucumis melo (Muskmelon).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; fabids; Cucurbitales; Cucurbitaceae; Benincaseae; Cucumis.
OX NCBI_TaxID=3656 {ECO:0000313|Proteomes:UP000089565, ECO:0000313|RefSeq:XP_008458297.1};
RN [1] {ECO:0000313|Proteomes:UP000089565}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. DHL92 {ECO:0000313|Proteomes:UP000089565};
RX PubMed=22753475; DOI=10.1073/pnas.1205415109;
RA Garcia-Mas J., Benjak A., Sanseverino W., Bourgeois M., Mir G.,
RA Gonzalez V.M., Henaff E., Camara F., Cozzuto L., Lowy E., Alioto T.,
RA Capella-Gutierrez S., Blanca J., Canizares J., Ziarsolo P.,
RA Gonzalez-Ibeas D., Rodriguez-Moreno L., Droege M., Du L.,
RA Alvarez-Tejado M., Lorente-Galdos B., Mele M., Yang L., Weng Y.,
RA Navarro A., Marques-Bonet T., Aranda M.A., Nuez F., Pico B., Gabaldon T.,
RA Roma G., Guigo R., Casacuberta J.M., Arus P., Puigdomenech P.;
RT "The genome of melon (Cucumis melo L.).";
RL Proc. Natl. Acad. Sci. U.S.A. 109:11872-11877(2012).
RN [2] {ECO:0000313|RefSeq:XP_008458297.1}
RP IDENTIFICATION.
RG RefSeq;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SIMILARITY: Belongs to the TRAFAC class myosin-kinesin ATPase
CC superfamily. Kinesin family. KIN-12 subfamily.
CC {ECO:0000256|ARBA:ARBA00034488}.
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DR RefSeq; XP_008458297.1; XM_008460075.1.
DR GeneID; 103497757; -.
DR KEGG; cmo:103497757; -.
DR eggNOG; ENOG502QR1R; Eukaryota.
DR InParanoid; A0A1S3C724; -.
DR OrthoDB; 472090at2759; -.
DR Proteomes; UP000089565; Unplaced.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-UniRule.
DR GO; GO:0008017; F:microtubule binding; IEA:InterPro.
DR GO; GO:0003777; F:microtubule motor activity; IEA:InterPro.
DR GO; GO:0007018; P:microtubule-based movement; IEA:InterPro.
DR CDD; cd01373; KISc_KLP2_like; 1.
DR Gene3D; 3.40.850.10; Kinesin motor domain; 1.
DR InterPro; IPR044986; KIF15/KIN-12.
DR InterPro; IPR019821; Kinesin_motor_CS.
DR InterPro; IPR001752; Kinesin_motor_dom.
DR InterPro; IPR036961; Kinesin_motor_dom_sf.
DR InterPro; IPR027417; P-loop_NTPase.
DR PANTHER; PTHR37739:SF18; KINESIN-LIKE PROTEIN KIN-12C; 1.
DR PANTHER; PTHR37739; KINESIN-LIKE PROTEIN KIN-12D; 1.
DR Pfam; PF00225; Kinesin; 1.
DR PRINTS; PR00380; KINESINHEAVY.
DR SMART; SM00129; KISc; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR PROSITE; PS00411; KINESIN_MOTOR_1; 1.
DR PROSITE; PS50067; KINESIN_MOTOR_2; 1.
PE 3: Inferred from homology;
KW ATP-binding {ECO:0000256|PROSITE-ProRule:PRU00283};
KW Coiled coil {ECO:0000256|SAM:Coils};
KW Motor protein {ECO:0000256|ARBA:ARBA00023175, ECO:0000256|PROSITE-
KW ProRule:PRU00283};
KW Nucleotide-binding {ECO:0000256|PROSITE-ProRule:PRU00283};
KW Reference proteome {ECO:0000313|Proteomes:UP000089565}.
FT DOMAIN 175..512
FT /note="Kinesin motor"
FT /evidence="ECO:0000259|PROSITE:PS50067"
FT REGION 1..36
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 81..117
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 2200..2222
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 839..893
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 1172..1250
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 1690..1773
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 1809..1871
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 1899..1926
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 2071..2196
FT /evidence="ECO:0000256|SAM:Coils"
FT COMPBIAS 1..19
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT BINDING 256..263
FT /ligand="ATP"
FT /ligand_id="ChEBI:CHEBI:30616"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00283"
SQ SEQUENCE 2222 AA; 253016 MW; 3CD8D84F35715063 CRC64;
MSKHLPVSKN SQPEYNENEL GVSPSGLHFP PPRTPFNIIA DPAQFQKEFH DSGFDSNLKL
QSTKADLFSD RKSEVSLKIN GNACTSNGTP RFSAQGRRVN SEPSSTHSTP AKSSSRVSLG
GAIVATGSKA PQLADGRAGS SYRFSRRISM PNTECPVDVS HIDLEEDPSF WKDHNVQVMI
RIRPLSTMER DSQGYGRCLR QESAKTLVWL GHPETRFTFD HIACEKISQE NLFKVAGQPM
VENCLSGYNS CMFAYGQTGS GKTYTMMGGI YELEGKLNED CGLTLRIFEH LFTRIGMEEK
SKRDVKLKYS CKCSFLEIYN EQITDLLEPS STNLQLREDS KKGVYVENLT EHSVSTINDV
VKLLLQGAAN RKMAATYMNS ESSRSHSVFT CIIESHWEKD SRTHLRFARL NLVDLAGSER
QKSSGAEGDR LKEAANINKS LSTLGLVIMS LVDLAHGKHR HIPYRDSRLT FLLQDSLGGN
SKTTVIANVS PSFCSANETL STLKFAQRAK QIQNNAKVNE CASGDETALQ RQILHLKGQL
SFLLKHSNFP RSILSSVPRL EEFGVSAPFD DYGALGNRMQ TENHKMKLME ASLIGASRRE
EVANTTIKKL EFEIEHMKRL AFQQEEDGQR TKMLLKFREE KIRQLELFLG GMVSADQYLL
DENKALAVEI KMLQAKIDRN PELTRVSLEN SKLTEQLQVY HNFYELGERE ALLTEVAELR
NELLVALGKN STISERDKYQ NETMSIKSYI QDDTLSYIAG SEENFENTLG QGSDDELGAK
PIFSRKDLTD AKMLAESMDS DNHMQAENHG CKQFKCCMVE NFIKQSDGTK CQNDGNLMNQ
HEDVDNKTLQ VKLENLTREL EEVRLSNIHY QENQNQQNQI EDVRQQVEME TASTILQLQE
EVETLQLELN DRLHGLAQEN TLLKDLLSAK NEEMRMLCID WETAMVELTS FLLDSSRSIR
DAHGQIEGIA NLFPEVNVGI SEQVQQAIKV CIEKEETILF LHKNLEDARL MVKEMELKLD
SLKEATLAFN ESEQMHDNIS AAGAKPLSPQ MTDENIMGEF LDKRLGVKNS PLIEAEKSAD
AAVTAVEWLS QPQELGCCNS IERQMPISKL DVSSQRSSHI FDNLMANTNE LLLEESDTVS
NMIWLGLTEL KNITIGHYAD MEMHISALHI YIQDLYSEYQ ELIQDMAREI HELRLKAETS
NESYKSLQFF KDKDQSAQKY WNIENQNSIL DQIKAKIYEA KNRLNILEDS IDRNTAGCGE
RYLDQYPVKE DGWSSDCSTS SSEISTESDT SRGKFLDYMN GGEGTTISLR KELYMTYNAI
RKLCMQIDTV LMHDIGGNSL SEEMDQGKTL FKLRMEKAEA GCSNTSKVIS IEEIKQDGGF
LTRFEEAQEA IKEADIMLNA LLRANANAKQ LTDIFKQAGE QLQIERDNLV DEVGQLKSSM
HLKDAENKLL HDQVCFNLEE VANSVSSLEG CISQTQRDVD EKFGIISCDI ISLRDEMLKS
VSNWKSLLED IFLEIMGREF ASFVIHQCYS KEICWQFAAQ FKADPNFLPL KWQRCLESTN
ASGSTCLTDK EDIMLINKIE KGRTELITGL EEVDGGFSYD DILYEKLALK KELRRKEVLL
EGLLFDFRLL QESTSKTKDM KDETDYSLSQ LQHELEIKAN QLDSVLVQQR KLEGLLTDTE
KALFLSNSKL DKAKETMTSI SEHNAQLKKQ VEDLYLQKFE AEKQLAEQQD VINKLENEIL
HLTSLEKRSV LSVEDIENDL SRVINERDQL HEQVCFLTDK LDIAYAMADE KEAVATEARQ
ESEASKLYAE EKEEEVKILE HSVEELESTI NMLETKVHEM DEEVEKNRTL RESLELEKKI
LRQRLLAVEN LSEDMDCGAE IVEHAQDQPR QPGNILLELL ETKSRIKLLE QERVEQDKEV
KRLKEYISEL VLHADAQAMK YQQKYTSLEV MVRDASKDHS NPMTAPALDK VEKNSARPRG
SSSPFRCISN LVHQMNLEKE HELSTARLRI EELELLATSR QKEICILNAR LAAAESMTHD
VIRDLLGVKL DLTKYANFID QYQVQKMVTE AHLQSQQFQE KEREVQDLRT QINDLHEERE
CYKSVLSKKE AEALHMQIAC EKLRERDHLL SSQNGILKTE NKNLKKKIVE LDDRGNTLHQ
TQSSQRDLRH SFLTKNDELT KRLANSKMLL SRVNDEMARY RIPRGSSSHH RSGGSGKEIS
HE
//
