ID   A0A1S3CRU5_CUCME        Unreviewed;      1103 AA.
AC   A0A1S3CRU5;
DT   12-APR-2017, integrated into UniProtKB/TrEMBL.
DT   12-APR-2017, sequence version 1.
DT   27-MAR-2024, entry version 36.
DE   SubName: Full=NF-X1-type zinc finger protein NFXL1 {ECO:0000313|RefSeq:XP_008466671.1};
GN   Name=LOC103503992 {ECO:0000313|RefSeq:XP_008466671.1};
OS   Cucumis melo (Muskmelon).
OC   Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC   Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC   rosids; fabids; Cucurbitales; Cucurbitaceae; Benincaseae; Cucumis.
OX   NCBI_TaxID=3656 {ECO:0000313|Proteomes:UP000089565, ECO:0000313|RefSeq:XP_008466671.1};
RN   [1] {ECO:0000313|Proteomes:UP000089565}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=cv. DHL92 {ECO:0000313|Proteomes:UP000089565};
RX   PubMed=22753475; DOI=10.1073/pnas.1205415109;
RA   Garcia-Mas J., Benjak A., Sanseverino W., Bourgeois M., Mir G.,
RA   Gonzalez V.M., Henaff E., Camara F., Cozzuto L., Lowy E., Alioto T.,
RA   Capella-Gutierrez S., Blanca J., Canizares J., Ziarsolo P.,
RA   Gonzalez-Ibeas D., Rodriguez-Moreno L., Droege M., Du L.,
RA   Alvarez-Tejado M., Lorente-Galdos B., Mele M., Yang L., Weng Y.,
RA   Navarro A., Marques-Bonet T., Aranda M.A., Nuez F., Pico B., Gabaldon T.,
RA   Roma G., Guigo R., Casacuberta J.M., Arus P., Puigdomenech P.;
RT   "The genome of melon (Cucumis melo L.).";
RL   Proc. Natl. Acad. Sci. U.S.A. 109:11872-11877(2012).
RN   [2] {ECO:0000313|RefSeq:XP_008466671.1}
RP   IDENTIFICATION.
RG   RefSeq;
RL   Submitted (NOV-2023) to UniProtKB.
CC   -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
CC   -!- SIMILARITY: Belongs to the NFX1 family.
CC       {ECO:0000256|ARBA:ARBA00007269}.
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DR   RefSeq; XP_008466671.1; XM_008468449.2.
DR   AlphaFoldDB; A0A1S3CRU5; -.
DR   GeneID; 103503992; -.
DR   KEGG; cmo:103503992; -.
DR   eggNOG; KOG1952; Eukaryota.
DR   InParanoid; A0A1S3CRU5; -.
DR   OrthoDB; 1412at2759; -.
DR   Proteomes; UP000089565; Unplaced.
DR   GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR   GO; GO:0003700; F:DNA-binding transcription factor activity; IEA:InterPro.
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR   CDD; cd06008; NF-X1-zinc-finger; 7.
DR   CDD; cd16492; RING-CH-C4HC3_NFX1-like; 1.
DR   InterPro; IPR034078; NFX1_fam.
DR   InterPro; IPR000967; Znf_NFX1.
DR   InterPro; IPR019787; Znf_PHD-finger.
DR   InterPro; IPR001841; Znf_RING.
DR   PANTHER; PTHR12360; NUCLEAR TRANSCRIPTION FACTOR, X-BOX BINDING 1 NFX1; 1.
DR   PANTHER; PTHR12360:SF12; TRANSCRIPTIONAL REPRESSOR NF-X1; 1.
DR   Pfam; PF01422; zf-NF-X1; 8.
DR   SMART; SM00438; ZnF_NFX; 8.
DR   SUPFAM; SSF57850; RING/U-box; 1.
DR   PROSITE; PS50016; ZF_PHD_2; 1.
DR   PROSITE; PS50089; ZF_RING_2; 1.
PE   3: Inferred from homology;
KW   Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW   Nucleus {ECO:0000256|ARBA:ARBA00023242};
KW   Reference proteome {ECO:0000313|Proteomes:UP000089565};
KW   Repeat {ECO:0000256|ARBA:ARBA00022737};
KW   Zinc {ECO:0000256|ARBA:ARBA00022833};
KW   Zinc-finger {ECO:0000256|ARBA:ARBA00022771, ECO:0000256|PROSITE-
KW   ProRule:PRU00175}.
FT   DOMAIN          126..187
FT                   /note="PHD-type"
FT                   /evidence="ECO:0000259|PROSITE:PS50016"
FT   DOMAIN          129..185
FT                   /note="RING-type"
FT                   /evidence="ECO:0000259|PROSITE:PS50089"
FT   REGION          1..106
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          964..1012
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          1041..1103
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        24..61
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        83..104
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        964..1001
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        1041..1089
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   1103 AA;  120704 MW;  BEE321AE01283B1E CRC64;
     MSSNVRNVRK DRSRIPASSA RKEWVPRGST TTTTTTETTD IHVNRPLNVN SNDNRNGLEL
     NSSPPHPVYR DRGNHGQRVY VGPRRNQRKD KEKDKEKSGD QGEKELRISN LPQLVHEIQE
     KLTKGTVECM ICYDMVRRSA PIWSCSSCFC IFHLTCIKKW ARAPTSTDLV AEKNQGLNWR
     CPGCQSVQLI SSKEIRYVCF CGKRQDPPSD LYLTPHSCGE PCGKPLDREM LVAGGSKEDL
     CPHNCVLQCH PGPCPPCKAF APPRLCPCGK KLITTRCSDR KSTLTCGQRC EKLLDCGRHW
     CEKICHVGTC DPCQVQVSAS CFCKKKKELV LCGSMTLKGE VNTEDGVFPC SSICGKSLNC
     GNHVCREICH PGPCGGCELM PDMIRTCYCG KTRLQDERTS CLDPIPTCSE LCEKLLPCGK
     HRCKEVCHAG DCAPCLVQVV QKCRCGSTSR NVECYKTSSP TDIFTCEKPC EWKKNCGRHR
     CSERCCPLSN SSYNHLGDWD PHFCVMRCGK KLRCRQHSCQ SLCHSGHCSP CPETIFTDLT
     CACGKTSIPP PLPCGTPPPS CQLPCSVPQP CGHSSTHSCH FGDCPPCTVP IAKECIGGHV
     VLRNIPCGSR DIRCNKLCGK TRQCGMHACN RTCHPPPCDT VAGSDSVQKT SCGQTCGAPR
     RDCRHTCTAP CHPSAPCPDA RCEFPVVITC SCGRITASVP CDAGGSSIGF NTDTLYASII
     QKLPVPLQPI EATGKKIPLG QRKLTCDEEC SKLERNRVLA DAFDITPPNL DALHFGDSSA
     TELLADLFRR DSKWVLAVEE RCKFLVLGKN RGGIGGLKVH VFCPMPKDKR DAVRLIAERW
     KVAINSVGWE PKRFITIHVT PKSKVPPRVL GIKGSTTTST LHPPPYDPLV DMDPRLVVSF
     PDLPRESDIS ALVLRFGGEC ELVWLNDKNA LAVFSDPARA ATAMRRLDHG TAYHGASLLQ
     NGGASASSNT NAWGGGENAK EGASKSSNPW KRAVVQDSSW KDTSWGDEEW SGPSIDVQAS
     VWKREAAPFS ASLNRWHALD TEPSVSSSTQ SSEHNLGNRV GNSSLGSESS TSRSLSSGGV
     MQVVTDDGTN MSEVADDWEK AYD
//