ID A0A1S3CXD3_DIACI Unreviewed; 393 AA.
AC A0A1S3CXD3;
DT 12-APR-2017, integrated into UniProtKB/TrEMBL.
DT 12-APR-2017, sequence version 1.
DT 27-MAR-2024, entry version 27.
DE RecName: Full=Innexin {ECO:0000256|RuleBase:RU010713};
GN Name=LOC103507053 {ECO:0000313|RefSeq:XP_008469711.1,
GN ECO:0000313|RefSeq:XP_026677816.1};
GN Synonyms=inx {ECO:0000256|RuleBase:RU010713};
OS Diaphorina citri (Asian citrus psyllid).
OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC Neoptera; Paraneoptera; Hemiptera; Sternorrhyncha; Psylloidea; Psyllidae;
OC Diaphorininae; Diaphorina.
OX NCBI_TaxID=121845 {ECO:0000313|Proteomes:UP000079169, ECO:0000313|RefSeq:XP_008469711.1};
RN [1] {ECO:0000313|RefSeq:XP_008469711.1, ECO:0000313|RefSeq:XP_026677816.1}
RP IDENTIFICATION.
RG RefSeq;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- FUNCTION: Structural component of the gap junctions.
CC {ECO:0000256|RuleBase:RU010713}.
CC -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000256|RuleBase:RU010713};
CC Multi-pass membrane protein {ECO:0000256|RuleBase:RU010713}. Cell
CC junction, gap junction {ECO:0000256|RuleBase:RU010713}. Membrane
CC {ECO:0000256|ARBA:ARBA00004141}; Multi-pass membrane protein
CC {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the pannexin family. {ECO:0000256|PROSITE-
CC ProRule:PRU00351, ECO:0000256|RuleBase:RU010713}.
CC -!- CAUTION: Lacks conserved residue(s) required for the propagation of
CC feature annotation. {ECO:0000256|PROSITE-ProRule:PRU00351,
CC ECO:0000256|RuleBase:RU010713}.
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DR RefSeq; XP_008469711.1; XM_008471489.3.
DR RefSeq; XP_026677816.1; XM_026822015.1.
DR STRING; 121845.A0A1S3CXD3; -.
DR PaxDb; 121845-A0A1S3CXD3; -.
DR GeneID; 103507053; -.
DR KEGG; dci:103507053; -.
DR OMA; VVKFSNM; -.
DR OrthoDB; 2873211at2759; -.
DR Proteomes; UP000079169; Unplaced.
DR GO; GO:0005921; C:gap junction; IEA:UniProtKB-SubCell.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0034220; P:monoatomic ion transmembrane transport; IEA:UniProtKB-KW.
DR InterPro; IPR000990; Innexin.
DR PANTHER; PTHR11893; INNEXIN; 1.
DR PANTHER; PTHR11893:SF37; INNEXIN INX3; 1.
DR Pfam; PF00876; Innexin; 1.
DR PRINTS; PR01262; INNEXIN.
DR PROSITE; PS51013; PANNEXIN; 1.
PE 3: Inferred from homology;
KW Cell junction {ECO:0000256|RuleBase:RU010713};
KW Gap junction {ECO:0000256|ARBA:ARBA00022868, ECO:0000256|PROSITE-
KW ProRule:PRU00351}; Ion channel {ECO:0000256|RuleBase:RU010713};
KW Ion transport {ECO:0000256|RuleBase:RU010713};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|PROSITE-
KW ProRule:PRU00351}; Reference proteome {ECO:0000313|Proteomes:UP000079169};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|PROSITE-
KW ProRule:PRU00351};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989, ECO:0000256|PROSITE-
KW ProRule:PRU00351}; Transport {ECO:0000256|RuleBase:RU010713}.
FT TRANSMEM 115..137
FT /note="Helical"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00351,
FT ECO:0000256|RuleBase:RU010713"
FT TRANSMEM 281..306
FT /note="Helical"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00351,
FT ECO:0000256|RuleBase:RU010713"
SQ SEQUENCE 393 AA; 44959 MW; 5920BD07D115687E CRC64;
MSVFAMVSAM AGFVKVRYLM DKAIIDNLVF RCHYRITSAM LFVSCVLVTA NNLIGDPINC
IADGAVPGHV INTYCWITST FTLPHQAHKP VGSHVIHPAV GSYVEGEDEK RYHTYYQWVP
FMLFFQGILF YVPHWIWKNL EENKVRMITD GMRGAIVTSK EDRRERQKRL VQYIIDTLHM
HNVYAAGYFF CEFLNFVNVV GNMILIDSFL GGTFFTYGTE VLKFTQLNQE NRTDPMVEVF
PRVTKCTFHK YGSSGSIQDH DALCILALNI LNEKIYILLW FWFYALAIMS FGAICYSLSV
ITLPSIRETI LIRRFRFGTP AGVSALIRRT QVGDFLLLHL LGQNMNNMFF GEILDELSTN
LHLGNNIPTA PSTLELSPIY PSDKLRLHKE TEA
//
