ID A0A1S3DAT6_DIACI Unreviewed; 385 AA.
AC A0A1S3DAT6;
DT 12-APR-2017, integrated into UniProtKB/TrEMBL.
DT 12-APR-2017, sequence version 1.
DT 27-MAR-2024, entry version 28.
DE SubName: Full=Acetylcholine receptor subunit alpha-like {ECO:0000313|RefSeq:XP_008477881.2};
GN Name=LOC103514754 {ECO:0000313|RefSeq:XP_008477881.2};
OS Diaphorina citri (Asian citrus psyllid).
OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC Neoptera; Paraneoptera; Hemiptera; Sternorrhyncha; Psylloidea; Psyllidae;
OC Diaphorininae; Diaphorina.
OX NCBI_TaxID=121845 {ECO:0000313|Proteomes:UP000079169, ECO:0000313|RefSeq:XP_008477881.2};
RN [1] {ECO:0000313|RefSeq:XP_008477881.2}
RP IDENTIFICATION.
RG RefSeq;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR RefSeq; XP_008477881.2; XM_008479659.3.
DR AlphaFoldDB; A0A1S3DAT6; -.
DR STRING; 121845.A0A1S3DAT6; -.
DR PaxDb; 121845-A0A1S3DAT6; -.
DR GeneID; 103514754; -.
DR KEGG; dci:103514754; -.
DR OMA; QENTEFR; -.
DR OrthoDB; 2872899at2759; -.
DR Proteomes; UP000079169; Unplaced.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0005230; F:extracellular ligand-gated monoatomic ion channel activity; IEA:InterPro.
DR GO; GO:0004888; F:transmembrane signaling receptor activity; IEA:InterPro.
DR CDD; cd19064; LGIC_TM_nAChR; 1.
DR Gene3D; 2.70.170.10; Neurotransmitter-gated ion-channel ligand-binding domain; 1.
DR Gene3D; 1.20.58.390; Neurotransmitter-gated ion-channel transmembrane domain; 2.
DR InterPro; IPR006202; Neur_chan_lig-bd.
DR InterPro; IPR036734; Neur_chan_lig-bd_sf.
DR InterPro; IPR006201; Neur_channel.
DR InterPro; IPR036719; Neuro-gated_channel_TM_sf.
DR InterPro; IPR038050; Neuro_actylchol_rec.
DR InterPro; IPR006029; Neurotrans-gated_channel_TM.
DR PANTHER; PTHR18945; NEUROTRANSMITTER GATED ION CHANNEL; 1.
DR PANTHER; PTHR18945:SF933; NICOTINIC ACETYLCHOLINE RECEPTOR ALPHA4, ISOFORM H; 1.
DR Pfam; PF02931; Neur_chan_LBD; 1.
DR Pfam; PF02932; Neur_chan_memb; 1.
DR SUPFAM; SSF90112; Neurotransmitter-gated ion-channel transmembrane pore; 1.
DR SUPFAM; SSF63712; Nicotinic receptor ligand binding domain-like; 1.
PE 4: Predicted;
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Receptor {ECO:0000313|RefSeq:XP_008477881.2};
KW Reference proteome {ECO:0000313|Proteomes:UP000079169};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 117..140
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 152..170
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 182..203
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 335..355
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 64..116
FT /note="Neurotransmitter-gated ion-channel ligand-binding"
FT /evidence="ECO:0000259|Pfam:PF02931"
FT DOMAIN 123..351
FT /note="Neurotransmitter-gated ion-channel transmembrane"
FT /evidence="ECO:0000259|Pfam:PF02932"
FT REGION 43..65
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 385 AA; 43670 MW; 8A72722559FDC8AC CRC64;
MVAEVDGPMS MMRSCVPAKD EHHHHPESFY PYHTAARSTE DLSRFKRESS RKNKDDLSPR
RPPHRRERVG VDLSEFYMSV EWDILEVPAV RNEKFYTCCD EPYLDITFNI TMRRKTLFYT
VNIIIPCMGI SFLTVLTFYL PSDSGEKVTL SISILISLHV FFLLVVEIIP PTSLVVPLLG
KYLIFAMILV SISICVTVVV LNVHFRSPQT HKMAPWVKRV FIQFLPRILV MRRPLYNPDG
SHLADGPLIG GSGGSCKIHG HVSLSNILTE AILSSSPQDD SKHLRPPAFS HAQCPPVMHR
SCFCVRFIAE HTRMQDDSTK VKEDWKYVAL VLDRLFLWIF TLAVLGGTAG IILQAPSLYD
DRVPIDSKFA EIANSNSQFK CPPPK
//
