ID A0A1S3DII1_DIACI Unreviewed; 1595 AA.
AC A0A1S3DII1;
DT 12-APR-2017, integrated into UniProtKB/TrEMBL.
DT 12-APR-2017, sequence version 1.
DT 27-MAR-2024, entry version 30.
DE SubName: Full=Rho GTPase-activating protein 190 {ECO:0000313|RefSeq:XP_008482595.1};
GN Name=LOC103519289 {ECO:0000313|RefSeq:XP_008482595.1};
OS Diaphorina citri (Asian citrus psyllid).
OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC Neoptera; Paraneoptera; Hemiptera; Sternorrhyncha; Psylloidea; Psyllidae;
OC Diaphorininae; Diaphorina.
OX NCBI_TaxID=121845 {ECO:0000313|Proteomes:UP000079169, ECO:0000313|RefSeq:XP_008482595.1};
RN [1] {ECO:0000313|RefSeq:XP_008482595.1}
RP IDENTIFICATION.
RG RefSeq;
RL Submitted (NOV-2023) to UniProtKB.
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DR RefSeq; XP_008482595.1; XM_008484373.3.
DR STRING; 121845.A0A1S3DII1; -.
DR PaxDb; 121845-A0A1S3DII1; -.
DR GeneID; 103519289; -.
DR KEGG; dci:103519289; -.
DR OMA; MRNSFGG; -.
DR OrthoDB; 5405671at2759; -.
DR Proteomes; UP000079169; Unplaced.
DR GO; GO:0005096; F:GTPase activator activity; IEA:UniProtKB-KW.
DR GO; GO:0007165; P:signal transduction; IEA:InterPro.
DR CDD; cd22207; pseudoGTPaseD_p190RhoGAP; 1.
DR CDD; cd00882; Ras_like_GTPase; 1.
DR Gene3D; 1.10.10.440; FF domain; 2.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR Gene3D; 1.10.555.10; Rho GTPase activation protein; 1.
DR InterPro; IPR002713; FF_domain.
DR InterPro; IPR036517; FF_domain_sf.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR039007; pG1.
DR InterPro; IPR008936; Rho_GTPase_activation_prot.
DR InterPro; IPR032835; RhoGAP-FF1.
DR InterPro; IPR000198; RhoGAP_dom.
DR InterPro; IPR045786; RhoGAP_pG1_pG2.
DR InterPro; IPR039006; RhoGAP_pG2.
DR PANTHER; PTHR46005; RHO GTPASE-ACTIVATING PROTEIN 190; 1.
DR PANTHER; PTHR46005:SF4; RHO GTPASE-ACTIVATING PROTEIN 190; 1.
DR Pfam; PF00620; RhoGAP; 1.
DR Pfam; PF16512; RhoGAP-FF1; 1.
DR Pfam; PF19518; RhoGAP_pG1_pG2; 3.
DR SMART; SM00324; RhoGAP; 1.
DR SUPFAM; SSF48350; GTPase activation domain, GAP; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR PROSITE; PS51676; FF; 1.
DR PROSITE; PS51852; PG1; 1.
DR PROSITE; PS51853; PG2; 1.
DR PROSITE; PS50238; RHOGAP; 1.
PE 4: Predicted;
KW GTPase activation {ECO:0000256|ARBA:ARBA00022468};
KW Reference proteome {ECO:0000313|Proteomes:UP000079169};
KW Repeat {ECO:0000256|ARBA:ARBA00022737}.
FT DOMAIN 262..451
FT /note="PG1 pseudoGTPase"
FT /evidence="ECO:0000259|PROSITE:PS51852"
FT DOMAIN 517..571
FT /note="FF"
FT /evidence="ECO:0000259|PROSITE:PS51676"
FT DOMAIN 785..945
FT /note="PG2 pseudoGTPase"
FT /evidence="ECO:0000259|PROSITE:PS51853"
FT DOMAIN 1398..1586
FT /note="Rho-GAP"
FT /evidence="ECO:0000259|PROSITE:PS50238"
FT REGION 1035..1140
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1215..1293
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1330..1361
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1373..1393
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1053..1067
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1068..1082
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1086..1140
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1219..1254
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1255..1271
FT /note="Basic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1339..1361
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1595 AA; 181326 MW; FEBEC9AB5DFAB80B CRC64;
MARKHDSTKF FNVSVVGLSG TEKEKGAVGI GKSCLCNRFI RNIADDYNVD HISVLSQSDF
SGRVVNNDHF LYWGETTKVT EDGQELNFQV IEQTEFIDDA SFQPFKGGKM EPYVKRCSAT
KLQSAEKLMY ICKNQLGIEK EYEQKVLHDG KISIDGFLCL FDVSVVPSRT VEKQVEVVAN
ILNNLVKTKK PIVVVTTKND DANETFVREL EKLVARKEYK GAIPVVETSA HENINVDLAF
IALAQLANDR NKGRVKIVSY NEAARGRREL LELTTDAFQS LIQPCHIGHR RGQCEDDEYE
LDCQLYSLEY RIIDGDVNLP QNSFQSSDFL PHGCFCVYSN SESFEYIRES LEKTLLSNLK
QEDRLPFQGL PIVTDYRALW STTMKKFSKN DEFVQFNKLF GVDTSQKLFR RHVKKLKDEF
LQKRKQGYLE MLPEILQELV PEISTLRDKD WSMVKQHIRE HPDFDSYFYK CPEDIPWTEH
ELEDEDDTRI PANVLDTVEA ENVFKNHATA LQHELKKLEW KKQFKQLLED TGYVTPGKHL
SEVRVLFMGR ECFEALSEDD CKYIYDKHQK ELVEKAKLNF QELLLENADL FYHFKSIAPV
GTITQEDIKE ITNALKEDSR YKALDRLDQD RKVMLFQHLG FVHCPIKEHC PAFPNCMDAL
IERILANKTH RPSSWNYNSG FLLNADSNQL NLVILGIGGL ADEVCNEIRV SLTTGALFLK
ELIYLQCPFI DVSIEEEPDP SAHVARFNTK LIVNALEQLI QSIKHRAGFI NNYQSVIECT
EPDIRIIMCM FCGDPYSVEN VLGPLLSHQC CFMSGDRSVI LETFLGTSKR KVEVIISSFH
GANAFREELV HGFILVYSTK RKASLATLNA FSMNIPNLPI QIMAVTDTGG ANAFFSSDLS
HQLITEGNAT ADRLQAHFMT STSSFQQKSA FYTPFFKEVW EKKPEIERAF HMEEPSNSHP
RYRIKMGASN GSYGDIYERI PADAMGMKDV YSPSYSHEHL VVSGSDDSES YSPLDNEDVK
LGDDFKMKGG LEVYSPPNTP PEPAPPDHIQ HNFANASHGS ETSSDEITSD MCDSRESLGT
HDSGWVDDSV FSSQTTQENG SSWGGVSSNY SQHAFTTGRR RHGSSRVQNT THTMNQPGKL
NMKDYSLVKD AIARVNLGGT KMNKFLYGGG GGGNAPLATP ENVDLGSEYA QVKDALTDMY
YEGDYMYTPV QDSLASNTKS KIRQRREKGR PTTFSDSDSE YSSLDRERHR SYDSKSRKSA
THKRMRKKRS AIPVPTPRVP TFSVPPVSGD YTSVTNEIND RIKKRNGSTS GHPSLLNEDS
SLDASSLHEM ISSPSYLMQK TREDEKSVRR KEKEKAKAEE KIEKRRIKEE KVKKLAEERE
KKKHKSKSAK PGATHTMVSL GDFIQPEHSV PLILEKCIQF IEHEGLDSEG IYRVPGNRAH
VDLLFQKFDE DTNTDINTLD IPVNAVATAL KDFFSKKLPP LFTEEHMAEL EDISIRGDRS
CRLLALRALL KKLPPANFEV LKFVFHHLVR VAENCKLNSM DSKNLAICWW PTLLPIEFSD
MGKFEQLRPH LEDIVQTMID QYPFLFCGEE AFVMV
//
