ID A0A1S3DSB6_DIACI Unreviewed; 139 AA.
AC A0A1S3DSB6;
DT 12-APR-2017, integrated into UniProtKB/TrEMBL.
DT 13-FEB-2019, sequence version 2.
DT 27-MAR-2024, entry version 29.
DE RecName: Full=RuvB-like helicase {ECO:0000256|RuleBase:RU363048};
DE EC=3.6.4.12 {ECO:0000256|RuleBase:RU363048};
GN Name=LOC103523850 {ECO:0000313|RefSeq:XP_008487086.2};
OS Diaphorina citri (Asian citrus psyllid).
OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC Neoptera; Paraneoptera; Hemiptera; Sternorrhyncha; Psylloidea; Psyllidae;
OC Diaphorininae; Diaphorina.
OX NCBI_TaxID=121845 {ECO:0000313|Proteomes:UP000079169, ECO:0000313|RefSeq:XP_008487086.2};
RN [1] {ECO:0000313|RefSeq:XP_008487086.2}
RP IDENTIFICATION.
RG RefSeq;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- FUNCTION: Proposed core component of the chromatin remodeling Ino80
CC complex which is involved in transcriptional regulation, DNA
CC replication and probably DNA repair. {ECO:0000256|RuleBase:RU363048}.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=ATP + H2O = ADP + H(+) + phosphate; Xref=Rhea:RHEA:13065,
CC ChEBI:CHEBI:15377, ChEBI:CHEBI:15378, ChEBI:CHEBI:30616,
CC ChEBI:CHEBI:43474, ChEBI:CHEBI:456216; EC=3.6.4.12;
CC Evidence={ECO:0000256|RuleBase:RU363048};
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|RuleBase:RU363048}.
CC -!- SIMILARITY: Belongs to the RuvB family.
CC {ECO:0000256|RuleBase:RU363048}.
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DR RefSeq; XP_008487086.2; XM_008488864.2.
DR AlphaFoldDB; A0A1S3DSB6; -.
DR STRING; 121845.A0A1S3DSB6; -.
DR PaxDb; 121845-A0A1S3DSB6; -.
DR KEGG; dci:103523850; -.
DR OrthoDB; 5479950at2759; -.
DR Proteomes; UP000079169; Unplaced.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0016887; F:ATP hydrolysis activity; IEA:RHEA.
DR GO; GO:0008094; F:ATP-dependent activity, acting on DNA; IEA:InterPro.
DR GO; GO:0004386; F:helicase activity; IEA:UniProtKB-KW.
DR GO; GO:0006325; P:chromatin organization; IEA:UniProtKB-KW.
DR GO; GO:0006281; P:DNA repair; IEA:UniProtKB-KW.
DR Gene3D; 2.40.50.360; RuvB-like helicase, domain II; 2.
DR InterPro; IPR012340; NA-bd_OB-fold.
DR InterPro; IPR027238; RuvB-like.
DR InterPro; IPR042487; RuvBL1/2_DNA/RNA_bd_dom.
DR InterPro; IPR010339; TIP49_P-loop.
DR PANTHER; PTHR11093:SF2; RUVB-LIKE 2; 1.
DR PANTHER; PTHR11093; RUVB-RELATED REPTIN AND PONTIN; 1.
DR Pfam; PF06068; TIP49; 1.
DR SUPFAM; SSF50249; Nucleic acid-binding proteins; 2.
PE 3: Inferred from homology;
KW ATP-binding {ECO:0000256|RuleBase:RU363048};
KW Chromatin regulator {ECO:0000256|RuleBase:RU363048};
KW DNA damage {ECO:0000256|RuleBase:RU363048};
KW DNA repair {ECO:0000256|RuleBase:RU363048};
KW Helicase {ECO:0000256|RuleBase:RU363048};
KW Hydrolase {ECO:0000256|RuleBase:RU363048};
KW Nucleotide-binding {ECO:0000256|RuleBase:RU363048};
KW Nucleus {ECO:0000256|RuleBase:RU363048};
KW Reference proteome {ECO:0000313|Proteomes:UP000079169};
KW Transcription {ECO:0000256|RuleBase:RU363048};
KW Transcription regulation {ECO:0000256|RuleBase:RU363048}.
FT DOMAIN 2..105
FT /note="TIP49 P-loop"
FT /evidence="ECO:0000259|Pfam:PF06068"
FT NON_TER 139
FT /evidence="ECO:0000313|RefSeq:XP_008487086.2"
SQ SEQUENCE 139 AA; 15057 MW; 680B5984188B63B3 CRC64;
MIEGEVVEIQ IERPATGLGS KVGKLTMKTT EMETSYDLGA KMIEAIGKEK VQAGDVITID
KATGKITRLG RSFTRARDYD ATGAQTRFVQ SCPDRRAPEA KTVVQAGDVI TIDKATGKIT
RLGRSFTRAR DYDATGAQT
//
