ID   A0A1S3DUH4_DIACI        Unreviewed;      1033 AA.
AC   A0A1S3DUH4;
DT   12-APR-2017, integrated into UniProtKB/TrEMBL.
DT   12-APR-2017, sequence version 1.
DT   27-MAR-2024, entry version 25.
DE   SubName: Full=Patched domain-containing protein 3 {ECO:0000313|RefSeq:XP_008487266.1};
GN   Name=LOC103524038 {ECO:0000313|RefSeq:XP_008487266.1};
OS   Diaphorina citri (Asian citrus psyllid).
OC   Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC   Neoptera; Paraneoptera; Hemiptera; Sternorrhyncha; Psylloidea; Psyllidae;
OC   Diaphorininae; Diaphorina.
OX   NCBI_TaxID=121845 {ECO:0000313|Proteomes:UP000079169, ECO:0000313|RefSeq:XP_008487266.1};
RN   [1] {ECO:0000313|RefSeq:XP_008487266.1}
RP   IDENTIFICATION.
RG   RefSeq;
RL   Submitted (NOV-2023) to UniProtKB.
CC   -!- SIMILARITY: Belongs to the patched family.
CC       {ECO:0000256|ARBA:ARBA00005585}.
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DR   RefSeq; XP_008487266.1; XM_008489044.2.
DR   AlphaFoldDB; A0A1S3DUH4; -.
DR   PaxDb; 121845-A0A1S3DUH4; -.
DR   GeneID; 103524038; -.
DR   KEGG; dci:103524038; -.
DR   OMA; MWHITFF; -.
DR   OrthoDB; 2876883at2759; -.
DR   Proteomes; UP000079169; Unplaced.
DR   GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR   Gene3D; 1.20.1640.10; Multidrug efflux transporter AcrB transmembrane domain; 2.
DR   InterPro; IPR003392; Ptc/Disp.
DR   InterPro; IPR000731; SSD.
DR   PANTHER; PTHR10796; PATCHED-RELATED; 1.
DR   PANTHER; PTHR10796:SF92; PATCHED-RELATED, ISOFORM A; 1.
DR   Pfam; PF02460; Patched; 1.
DR   SUPFAM; SSF82866; Multidrug efflux transporter AcrB transmembrane domain; 2.
DR   PROSITE; PS50156; SSD; 1.
PE   3: Inferred from homology;
KW   Membrane {ECO:0000256|SAM:Phobius};
KW   Reference proteome {ECO:0000313|Proteomes:UP000079169};
KW   Transmembrane {ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM        30..51
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        272..293
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        305..327
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        375..395
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        407..432
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        498..520
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        707..725
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        732..752
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        758..780
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        801..822
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        834..856
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   DOMAIN          272..429
FT                   /note="SSD"
FT                   /evidence="ECO:0000259|PROSITE:PS50156"
FT   REGION          931..1033
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        933..953
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        954..973
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        979..993
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   1033 AA;  117581 MW;  A3E0646248918BF3 CRC64;
     MAGCGLKCVD NTLKRLFFKL GVFIARHPGY FIIVPILLTI ICITGFQRIF FEMDPEYLFS
     PQHGPGKTER AIVEQYFKMN YSARFNPTRI TRPGRFGRII AVPKHGDTML TKEIWKELRL
     IDEIVHNTSI VFGEDDQVYR YDDICAKWVD SCFPNDILNL DYVIEEVETK ALNLTFPIMF
     NPVTWDAHAF PVYFGATEIS DEGTIIRVPA LQLVYFVTAD TKSQDARGSK WEEAFLDAIG
     KAEESGVFKH ISTARFASRT LDIELEKNTR TVVPYFSSTF LIMASFSVIT LLMTDWVRSK
     PYLGLMGNVS TAMAIVAAFG AAVYLGIPFI GINFVSPLLM CSVGIDDTFV MLAAWRRTPI
     TMSVPERMGH MMAEAAVSIT ITSLTDIVSF SIGTANPFPS IQIFCMYSGL AVCFIFAWHC
     TFFAACVAIA GYAEEKNLHA ITCRKVTPVS LSGHKSWLYR LFCSGGINPK DPDNPEDNPD
     NAIMVWFRDN LAWYINQWPI KLLVILVFFA YLGGALYGTT QLQEGLQRRK LSRKDSYSIE
     FYEREDFYFR EFPYRIQVII EGELPYWDVN VQNQIENLTK TFEASSFISA PLYTESWLRS
     FVSYVRRNQD FLNVTIDTRE GFLKTLNDLW LFKPNPFSLD IKFNDDGTKI IASRFMIQAV
     NITDGNMEKE MVKELRRIAH ESSLNVSVFH PYFVFFDQFE LVRPTTIQSM LGGSVTMMFI
     SFIFIPNILC SMWVAFSIAS IGTGVLGYMA LWSVNLDSIS MINLIMCTGF SVDFTAHICY
     SYMSSSSDDP KERVREALYS VGLPIFQGAV STILGVSALI LADSYIFLVF FKMIFMVILF
     GALHGMFLLP VLLSIFGPGS CTRRKKSISD IEKTFPHPYC IPHPSLHPMT HMNGKSHFGG
     VPLHGMVQAS PRIVMSTYDG DTRGKFIVDS VENDQGLGTS EDSSESSSSR SQKQRQKMME
     DDERQRRKYV EGWRKSSVPN VNEYPNRTSF HNAGYLSDDE VRPYRGGKTS QYQNNHNRSR
     EPRQHYTRKD HRY
//