ID A0A1S3E1X5_CICAR Unreviewed; 1159 AA.
AC A0A1S3E1X5;
DT 12-APR-2017, integrated into UniProtKB/TrEMBL.
DT 12-APR-2017, sequence version 1.
DT 27-MAR-2024, entry version 32.
DE SubName: Full=TMV resistance protein N isoform X1 {ECO:0000313|RefSeq:XP_012569066.1, ECO:0000313|RefSeq:XP_012569068.1};
GN Name=LOC101493284 {ECO:0000313|RefSeq:XP_012569066.1,
GN ECO:0000313|RefSeq:XP_012569068.1, ECO:0000313|RefSeq:XP_012569069.1,
GN ECO:0000313|RefSeq:XP_012569071.1, ECO:0000313|RefSeq:XP_012569072.1,
GN ECO:0000313|RefSeq:XP_027188764.1, ECO:0000313|RefSeq:XP_027188765.1};
OS Cicer arietinum (Chickpea) (Garbanzo).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; fabids; Fabales; Fabaceae; Papilionoideae; 50 kb inversion clade;
OC NPAAA clade; Hologalegina; IRL clade; Cicereae; Cicer.
OX NCBI_TaxID=3827 {ECO:0000313|Proteomes:UP000087171, ECO:0000313|RefSeq:XP_012569066.1};
RN [1] {ECO:0000313|RefSeq:XP_012569066.1, ECO:0000313|RefSeq:XP_012569068.1}
RP IDENTIFICATION.
RC TISSUE=Etiolated seedlings {ECO:0000313|RefSeq:XP_012569066.1,
RC ECO:0000313|RefSeq:XP_012569068.1};
RG RefSeq;
RL Submitted (NOV-2023) to UniProtKB.
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DR RefSeq; XP_012569065.1; XM_012713611.1.
DR RefSeq; XP_012569066.1; XM_012713612.2.
DR RefSeq; XP_012569067.1; XM_012713613.1.
DR RefSeq; XP_012569068.1; XM_012713614.2.
DR RefSeq; XP_012569069.1; XM_012713615.2.
DR RefSeq; XP_012569070.1; XM_012713616.1.
DR RefSeq; XP_012569071.1; XM_012713617.2.
DR RefSeq; XP_012569072.1; XM_012713618.2.
DR RefSeq; XP_012569073.1; XM_012713619.1.
DR RefSeq; XP_027188764.1; XM_027332963.1.
DR RefSeq; XP_027188765.1; XM_027332964.1.
DR PaxDb; 3827-XP_004492462-1; -.
DR GeneID; 101493284; -.
DR eggNOG; ENOG502R41B; Eukaryota.
DR OrthoDB; 943894at2759; -.
DR Proteomes; UP000087171; Chromosome Ca3.
DR GO; GO:0043531; F:ADP binding; IEA:InterPro.
DR GO; GO:0008757; F:S-adenosylmethionine-dependent methyltransferase activity; IEA:UniProt.
DR GO; GO:0006952; P:defense response; IEA:UniProtKB-KW.
DR GO; GO:0007165; P:signal transduction; IEA:InterPro.
DR Gene3D; 1.10.8.430; Helical domain of apoptotic protease-activating factors; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR Gene3D; 3.80.10.10; Ribonuclease Inhibitor; 3.
DR Gene3D; 3.40.50.10140; Toll/interleukin-1 receptor homology (TIR) domain; 1.
DR InterPro; IPR042197; Apaf_helical.
DR InterPro; IPR044974; Disease_R_plants.
DR InterPro; IPR001611; Leu-rich_rpt.
DR InterPro; IPR011713; Leu-rich_rpt_3.
DR InterPro; IPR032675; LRR_dom_sf.
DR InterPro; IPR002182; NB-ARC.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR000157; TIR_dom.
DR InterPro; IPR035897; Toll_tir_struct_dom_sf.
DR InterPro; IPR036390; WH_DNA-bd_sf.
DR PANTHER; PTHR11017:SF290; ADP-RIBOSYL CYCLASE_CYCLIC ADP-RIBOSE HYDROLASE; 1.
DR PANTHER; PTHR11017; LEUCINE-RICH REPEAT-CONTAINING PROTEIN; 1.
DR Pfam; PF07725; LRR_3; 1.
DR Pfam; PF13855; LRR_8; 1.
DR Pfam; PF00931; NB-ARC; 1.
DR Pfam; PF01582; TIR; 1.
DR PRINTS; PR00364; DISEASERSIST.
DR SMART; SM00255; TIR; 1.
DR SUPFAM; SSF52058; L domain-like; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR SUPFAM; SSF52200; Toll/Interleukin receptor TIR domain; 1.
DR SUPFAM; SSF46785; Winged helix' DNA-binding domain; 1.
DR PROSITE; PS51450; LRR; 1.
DR PROSITE; PS50104; TIR; 1.
PE 4: Predicted;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Plant defense {ECO:0000256|ARBA:ARBA00022821};
KW Reference proteome {ECO:0000313|Proteomes:UP000087171}.
FT DOMAIN 31..197
FT /note="TIR"
FT /evidence="ECO:0000259|PROSITE:PS50104"
FT REGION 1..21
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1159 AA; 133189 MW; 05150F2AF665B988 CRC64;
MSKRTFGDII GEGGSSSSSS KEFDSIQSYR YIYDVFISFR GVDTRNTFVD HLYAHLIRKG
IFVFKDDKQL HKGNSISRQL LQAIQHSRIS IIVFSKDYAS STWCLDEMAA IAECHRELKQ
PVFPIFYDVD PSCVRKQIGL YESAFLLLAE QFKHDPHKVD GWKRAMTCLG GSAGWDVRNK
LEFEEIEKIV QAVIKTLGHK FSGFADDLIG MQPRVEALKS ILRLSSEDDG FRVLGIWGMG
GIGKTTLATV LYDTISHYYQ FGACCFIENV STIYRDGGAT AVQKQILRQT LKEKNLDAYS
SSEISGIIIN RLYNRKLLVV LDDVDQFEQL QELHINPKLL RPGSRIIITT RDMHILELYG
VDRIYEAELM NDNDAHDLLC RKAFKSDNSR SPFVELIPKV LKYTQGLPLA IRIMGSFLFN
RNAMQWRATF DGLQNNPDKR IMKVLQMSFE GLQLREREIF LHVACFFEGE REDYVRRILH
ACGLQPNIGI PLIAEKSLIT IRNQVICMHK MLLELGKQIV QGQHLDEPRF WNRLWLYRDF
HHVMMTKVEA TETKAIVLDQ KEDGFKFSKL RVEDLSKMEH LKLLILNHKN FSGKPIFLSN
SLYYFSWNGY PFTALPSNFQ PYDLVELNMP DSNIEQLWEG IQCLPCLKRM DLSNSKNLKM
TPCFDGILNL ERLDLTGCIN LLQVHPSIGL LSELVFLSLQ KCSSLVHLDF GSASRLWSLR
VLLLSGCTKL KSTPDFTGAI NLEYLDVDHC ASLFTFDGSL AKLRVLSLRD CTNLVRLGDS
LDKMTSLTTL DLCGCLKYKC LPVNSAMKSL VFLDLSFCNI SNLPQAIGEL RGLERLNLQG
NNFTAIPSLQ CLSNLAYLNL SYCHCLQRLP QLPTTSGPSD SMGIYFKTTS GSRDHRSGLY
VFDCRKIFGG SIWISSIDHQ YEWLQRLLKE PRHFRCGFDI VLPFPCYGSA EIPMWFDHRY
KGGSIIRIKN FDVNVDWVGF VFFVQFEVRY PMPNSASSQH PYPFYLSFES EHTEERFDMP
LSLKSNKVDG SPSEYCWTIY ISQEHCHFVK TEAQITFKAY QGLIMKEWGF HMLTEKERKY
VDQSNMKKIR LWNMPRKDMK DMLTRGTRLQ IEKVGESNFN NNNIGTKIQL PYNWLVSSED
DVENDEAKGK EISLFNLGL
//
