ID A0A1S3E6B9_CICAR Unreviewed; 341 AA.
AC A0A1S3E6B9;
DT 12-APR-2017, integrated into UniProtKB/TrEMBL.
DT 12-APR-2017, sequence version 1.
DT 27-MAR-2024, entry version 29.
DE SubName: Full=Eukaryotic translation initiation factor 2 subunit alpha homolog isoform X1 {ECO:0000313|RefSeq:XP_004500513.1};
DE SubName: Full=Eukaryotic translation initiation factor 2 subunit alpha homolog isoform X2 {ECO:0000313|RefSeq:XP_012571361.1};
GN Name=LOC101507300 {ECO:0000313|RefSeq:XP_004500513.1,
GN ECO:0000313|RefSeq:XP_012571361.1};
OS Cicer arietinum (Chickpea) (Garbanzo).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; fabids; Fabales; Fabaceae; Papilionoideae; 50 kb inversion clade;
OC NPAAA clade; Hologalegina; IRL clade; Cicereae; Cicer.
OX NCBI_TaxID=3827 {ECO:0000313|RefSeq:XP_012571361.1};
RN [1] {ECO:0000313|RefSeq:XP_004500513.1, ECO:0000313|RefSeq:XP_012571361.1}
RP IDENTIFICATION.
RC TISSUE=Etiolated seedlings {ECO:0000313|RefSeq:XP_004500513.1,
RC ECO:0000313|RefSeq:XP_012571361.1};
RG RefSeq;
RL Submitted (SEP-2023) to UniProtKB.
CC -!- SIMILARITY: Belongs to the eIF-2-alpha family.
CC {ECO:0000256|ARBA:ARBA00007223}.
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DR RefSeq; XP_004500513.1; XM_004500456.3.
DR RefSeq; XP_012571361.1; XM_012715907.2.
DR RefSeq; XP_012571362.1; XM_012715908.1.
DR STRING; 3827.A0A1S3E6B9; -.
DR PaxDb; 3827-XP_004500513-1; -.
DR GeneID; 101507300; -.
DR KEGG; cam:101507300; -.
DR eggNOG; KOG2916; Eukaryota.
DR OrthoDB; 4371132at2759; -.
DR Proteomes; UP000087171; Chromosome Ca5.
DR GO; GO:0003723; F:RNA binding; IEA:InterPro.
DR GO; GO:0003743; F:translation initiation factor activity; IEA:UniProtKB-KW.
DR CDD; cd04452; S1_IF2_alpha; 1.
DR Gene3D; 3.30.70.1130; EIF_2_alpha; 1.
DR Gene3D; 2.40.50.140; Nucleic acid-binding proteins; 1.
DR InterPro; IPR012340; NA-bd_OB-fold.
DR InterPro; IPR003029; S1_domain.
DR InterPro; IPR044126; S1_IF2_alpha.
DR InterPro; IPR024055; TIF2_asu_C.
DR InterPro; IPR024054; TIF2_asu_middle_sf.
DR InterPro; IPR011488; TIF_2_asu.
DR PANTHER; PTHR10602; EUKARYOTIC TRANSLATION INITIATION FACTOR 2 SUBUNIT 1; 1.
DR PANTHER; PTHR10602:SF0; EUKARYOTIC TRANSLATION INITIATION FACTOR 2 SUBUNIT 1; 1.
DR Pfam; PF07541; EIF_2_alpha; 1.
DR Pfam; PF00575; S1; 1.
DR SMART; SM00316; S1; 1.
DR SUPFAM; SSF110993; eIF-2-alpha, C-terminal domain; 1.
DR SUPFAM; SSF116742; eIF2alpha middle domain-like; 1.
DR SUPFAM; SSF50249; Nucleic acid-binding proteins; 1.
DR PROSITE; PS50126; S1; 1.
PE 3: Inferred from homology;
KW Initiation factor {ECO:0000256|ARBA:ARBA00022540,
KW ECO:0000313|RefSeq:XP_004500513.1};
KW Protein biosynthesis {ECO:0000256|ARBA:ARBA00022917};
KW Reference proteome {ECO:0000313|Proteomes:UP000087171}.
FT DOMAIN 18..89
FT /note="S1 motif"
FT /evidence="ECO:0000259|PROSITE:PS50126"
FT REGION 304..341
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 313..329
FT /note="Acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 341 AA; 38710 MW; 515DBB2F986605AD CRC64;
MAPNLECRMY EARYPEVDMA VMIQVKNIAD MGAYVSLLEY NNIEGMILFS ELSRRRIRSV
SSLIKVGRIE PVMVLRVDKE KGYIDLSKRR VSEEDIQACE ERYNKSKLVH SIMRHVAETL
NIDLEELYVH IGWPLYRKYG HAFEAFKIIV TDPDTVLSTL MREIKEVGPD GQEVTKVVPA
VSEEVKDSLV KNIRRRMTPQ PLKIRADIEM KCFQFDGVIH IKEAMRKAEA AGNDDCPVKI
KLVAPPLYVL TTQTLDKEQG ILVLNNAIAC CTESIEKHKG KLLVKEAARA VSERDDKLLA
EHMAKLRQDN EEVSGDEDSE EEEDTGMGEI DVENNGTGIT E
//
