ID A0A1S3ENA5_DIPOR Unreviewed; 504 AA.
AC A0A1S3ENA5;
DT 12-APR-2017, integrated into UniProtKB/TrEMBL.
DT 12-APR-2017, sequence version 1.
DT 27-MAR-2024, entry version 25.
DE SubName: Full=Autophagy-related protein 16-1 isoform X2 {ECO:0000313|RefSeq:XP_012865863.1};
GN Name=Atg16l1 {ECO:0000313|RefSeq:XP_012865863.1};
OS Dipodomys ordii (Ord's kangaroo rat).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Glires; Rodentia; Castorimorpha; Heteromyidae;
OC Dipodomyinae; Dipodomys.
OX NCBI_TaxID=10020 {ECO:0000313|Proteomes:UP000081671, ECO:0000313|RefSeq:XP_012865863.1};
RN [1] {ECO:0000313|RefSeq:XP_012865863.1}
RP IDENTIFICATION.
RC TISSUE=Kidney {ECO:0000313|RefSeq:XP_012865863.1};
RG RefSeq;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SIMILARITY: Belongs to the WD repeat ATG16 family.
CC {ECO:0000256|ARBA:ARBA00009271}.
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DR RefSeq; XP_012865863.1; XM_013010409.1.
DR AlphaFoldDB; A0A1S3ENA5; -.
DR GeneID; 105981288; -.
DR CTD; 55054; -.
DR OrthoDB; 458014at2759; -.
DR Proteomes; UP000081671; Unplaced.
DR GO; GO:0000045; P:autophagosome assembly; IEA:InterPro.
DR CDD; cd22887; Atg16_CCD; 1.
DR CDD; cd00200; WD40; 1.
DR Gene3D; 1.20.5.170; -; 1.
DR Gene3D; 2.130.10.10; YVTN repeat-like/Quinoprotein amine dehydrogenase; 2.
DR InterPro; IPR045160; ATG16.
DR InterPro; IPR013923; Autophagy-rel_prot_16_dom.
DR InterPro; IPR020472; G-protein_beta_WD-40_rep.
DR InterPro; IPR015943; WD40/YVTN_repeat-like_dom_sf.
DR InterPro; IPR019775; WD40_repeat_CS.
DR InterPro; IPR036322; WD40_repeat_dom_sf.
DR InterPro; IPR001680; WD40_rpt.
DR PANTHER; PTHR19878; AUTOPHAGY PROTEIN 16-LIKE; 1.
DR PANTHER; PTHR19878:SF6; AUTOPHAGY-RELATED PROTEIN 16-1; 1.
DR Pfam; PF08614; ATG16; 1.
DR Pfam; PF00400; WD40; 5.
DR PRINTS; PR00320; GPROTEINBRPT.
DR SMART; SM00320; WD40; 7.
DR SUPFAM; SSF50978; WD40 repeat-like; 1.
DR PROSITE; PS00678; WD_REPEATS_1; 1.
DR PROSITE; PS50082; WD_REPEATS_2; 6.
DR PROSITE; PS50294; WD_REPEATS_REGION; 4.
PE 3: Inferred from homology;
KW Coiled coil {ECO:0000256|SAM:Coils};
KW Reference proteome {ECO:0000313|Proteomes:UP000081671};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW WD repeat {ECO:0000256|ARBA:ARBA00022574, ECO:0000256|PROSITE-
KW ProRule:PRU00221}.
FT DOMAIN 2..122
FT /note="Autophagy-related protein 16"
FT /evidence="ECO:0000259|Pfam:PF08614"
FT REPEAT 215..247
FT /note="WD"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00221"
FT REPEAT 259..300
FT /note="WD"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00221"
FT REPEAT 301..342
FT /note="WD"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00221"
FT REPEAT 359..381
FT /note="WD"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00221"
FT REPEAT 437..468
FT /note="WD"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00221"
FT REPEAT 470..504
FT /note="WD"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00221"
FT REGION 164..204
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 26..146
FT /evidence="ECO:0000256|SAM:Coils"
FT COMPBIAS 173..191
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 504 AA; 56225 MW; 2425EEB1EA732124 CRC64;
MSQLRIKHQE ELTELHKKRG ELAQLVIDLN NQMQQKDREI QMNEAKIAEC LQTISDLETE
CLDLRSKLQD LEIANQTLKD EYDALQITFT ALEEKLRKTT EENQELVTRW MAEKAQEANR
LNAENEKDSR RRQARLQKEL AEAAKEPLPV EQDDDIEVIV DETSDHPEET SPVRTVTRTA
TRRSVSSFPV PQDNMDAHPA SGKDARVPTT AVCVFEAHDG EVNAVQFSPG SRLLATGGMD
RRVKLWEAFG DKCEFKGSLS GSNAGITSIE FDSAGAYLLA ASNDFASRIW TVDDYRLRHT
LTGHSGKVLS AKFLLDNARI VSGSHDRTLK LWDLRSKVCI KTVFAGSSCN DIVCTEQCVM
SGHFDKKIRF WDIRSESVVR EMELLGKITA LDLNPERTEL LSCSRDDLLK IIDLRTNAVK
QTFSAPGFKC GSDWTRVVFS PDGGYVAAGS AEGSLYVWNV LTGKVEKVLS KQHSSSINAV
AWAPSGLHVI SVDKGSKAVL WAQP
//
